Abstract:
:Much of our understanding of the epidemiologic features of infection with Blastomyces dermatitidis has come from cluster and outbreak investigations which have established the association of human disease with recreational pursuits and the presence of infectious microfoci in areas of moist soil with high organic content. This report describes the clustering of eight cases of pulmonary blastomycosis without an apparent common source exposure which occurred during a 90 day period in a 96 square mile area (population 4,450) within Oconto County, Wisconsin. We conclude that multiple high-risk environmental foci may have existed following a sustained five-year period of diminished precipitation in the cluster area. A case-control study which included family and community controls concluded that multiple earth-disturbing activities engaged in by case-patients was statistically associated with illness. Lymphocyte-proliferation assays of whole blood samples detected previously unrecognized infection with B. dermatititidis among five of 32 family controls.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Proctor ME,Klein BS,Jones JM,Davis JPdoi
10.1023/a:1014515230994keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
113-20issue
3eissn
0301-486Xissn
1573-0832journal_volume
153pub_type
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