[Adrenergic activity and glycometabolic compensation in patients with diabetes mellitus].

Abstract:

:In an assessment of the degree of adrenergic activity in the course of diabetes mellitus, plasma levels and urinary excretion of norepinephrine and epinephrine were determined in 20 normal subjects and 47 diabetics: 11 in good control (group I), 23 in poor control (group II), 13 with frank ketoacidosis (group III). The study was repeated in groups II and III once good glycometabolic control had been achieved. Slightly above normal catecholamine levels were noted in group I, while there was a marked increase in group II. Group III shaved an enormous increase by comparison with the other two groups. After medical treatment values in group III fell to within the group I range. The conclusion is drawn that a close relationship exists between adrenergic acitivity and the degree of control of diabetes. The sympathetic nervous system, therefore, interferes in the course of diabetes with blood sugar control via numerous, complex mechanisms.

journal_name

Minerva Med

journal_title

Minerva medica

authors

Bolli G,Cartechini MG,Compagnucci P,Massi-Benedetti M,Filipponi P,Nicoletti I,De Feo P,Angeletti G

keywords:

subject

Has Abstract

pub_date

1979-12-08 00:00:00

pages

3783-95

issue

55

eissn

0026-4806

issn

1827-1669

journal_volume

70

pub_type

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