Abstract:
:In an assessment of the degree of adrenergic activity in the course of diabetes mellitus, plasma levels and urinary excretion of norepinephrine and epinephrine were determined in 20 normal subjects and 47 diabetics: 11 in good control (group I), 23 in poor control (group II), 13 with frank ketoacidosis (group III). The study was repeated in groups II and III once good glycometabolic control had been achieved. Slightly above normal catecholamine levels were noted in group I, while there was a marked increase in group II. Group III shaved an enormous increase by comparison with the other two groups. After medical treatment values in group III fell to within the group I range. The conclusion is drawn that a close relationship exists between adrenergic acitivity and the degree of control of diabetes. The sympathetic nervous system, therefore, interferes in the course of diabetes with blood sugar control via numerous, complex mechanisms.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Bolli G,Cartechini MG,Compagnucci P,Massi-Benedetti M,Filipponi P,Nicoletti I,De Feo P,Angeletti Gkeywords:
subject
Has Abstractpub_date
1979-12-08 00:00:00pages
3783-95issue
55eissn
0026-4806issn
1827-1669journal_volume
70pub_type
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