Abstract：
:We studied an adenosine deaminase (ADA) activity in the cerebrospinal fluid (CSF) of 182 patients with meningitis. The patients were subdivided into four groups, (1) 36 cases of tuberculous meningitis; (2) 130 cases of viral or aseptic meningitis; (3) nine cases of bacterial meningitis; (4) seven cases of cryptococcal meningitis. Mean+/-S.D. ADA activity was 12.76+/-7.53 U/l in group 1; 2.58+/-2.37 U/l in group 2; 7.38+/-3.27 U/l in group 3; 7.42+/-4.38 U/l in group 4. Comparing the ADA activity in each group with the other groups, the difference is significant (P<0.001), except between groups 3 and 4. The sensitivity of the test for group 1 compared with group 2 was 0.83 and the specificity was 0.95 when a cut-off value of 7 U/l was used. When group 1 was compared with groups 3 and 4, the sensitivity was 0.58 and the specificity was 0.89 and 0.71 with groups 3 and 4, respectively, when a cut-off value of 10 U/l was used. Values >15 U/l were not observed in any of the non-tuberculous meningitis patients; therefore, ADA activity >15 U/l could be a strong indication of tuberculous meningitis. We conclude that a determination of CSF ADA can aid in the early differential diagnosis of tuberculous meningitis.
journal_name
Clin Neurol Neurosurgjournal_title
Clinical neurology and neurosurgeryauthors
Choi SH,Kim YS,Bae IG,Chung JW,Lee MS,Kang JM,Ryu J,Woo JHdoi
10.1016/s0303-8467(01)00159-7keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
10-5issue
1eissn
0303-8467issn
1872-6968pii
S0303846701001597journal_volume
104pub_type
杂志文章abstract：:The case of a 27-year-old man is reported in whom neurological symptoms of obstruction of spinal arteries (myelomalacia) was the initial picture of acute leukemia. A review is given of the literature. There are no other reported cases of this very rare association. ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(89)80016-2
更新日期：1989-01-01 00:00:00
abstract：:We studied contrast sensitivity function in normal subjects and in three illustrative cases with various neurological disorders. This was done by measuring contrast sensitivity over a range of spatial frequencies for vertical sinewave grating stimuli. It is demonstrated that contrast sensitivity function can give info...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
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abstract：OBJECTIVES:To evaluate the efficacy and safety of pre-operative Halo-gravity traction in the treatment of severe neurofibromatosis type 1 and congenital scoliosis patients with thoracic rotatory subluxation. PATIENTS AND METHODS:Patients with neurofibromatosis type 1 and congenital scoliosis undergoing Halo-gravity tr...
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journal_title：Clinical neurology and neurosurgery
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doi：10.1016/j.clineuro.2009.10.005
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2008.04.001
更新日期：2008-07-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
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doi：10.1016/j.clineuro.2017.07.011
更新日期：2017-09-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(97)00073-5
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(97)00060-7
更新日期：1997-10-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
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journal_title：Clinical neurology and neurosurgery
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
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更新日期：2016-10-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
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更新日期：2014-09-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
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更新日期：1997-10-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2015.10.017
更新日期：2015-12-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(97)00086-3
更新日期：1997-12-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,多中心研究,随机对照试验
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journal_title：Clinical neurology and neurosurgery
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journal_title：Clinical neurology and neurosurgery
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journal_title：Clinical neurology and neurosurgery
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journal_title：Clinical neurology and neurosurgery
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journal_title：Clinical neurology and neurosurgery
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doi：10.1016/j.clineuro.2014.09.023
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
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更新日期：1995-02-01 00:00:00
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更新日期：2021-01-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
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更新日期：2010-05-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
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doi：10.1016/j.clineuro.2009.04.002
更新日期：2009-09-01 00:00:00
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更新日期：2014-02-01 00:00:00
