Abstract:
:Statistical evidence of reduced coronary heart disease in areas of high wine consumption has led to the widespread belief that wine affords a protective effect. Although moderate drinking of any alcohol helps to reduce the incidence of coronary heart disease, there is no clear evidence that red wine confers an additional benefit. Here we show that red wines strongly inhibit the synthesis of endothelin-1, a vasoactive peptide that is crucial in the development of coronary atherosclerosis. Our findings indicate that components specific to red wine may help to prevent coronary heart disease.
journal_name
Naturejournal_title
Natureauthors
Corder R,Douthwaite JA,Lees DM,Khan NQ,Viseu Dos Santos AC,Wood EG,Carrier MJdoi
10.1038/414863akeywords:
subject
Has Abstractpub_date
2001-12-20 00:00:00pages
863-4issue
6866eissn
0028-0836issn
1476-4687pii
414863ajournal_volume
414pub_type
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