Non-Hodgkin's lymphoma: review of conventional treatments.

abstract：:Bone grafts are widely used for augmentation procedures in oral and maxillofacial surgery, with autogenous bone being the gold standard. Recently, the focus of research has shifted towards synthetic bone substitutes, as no second surgery is needed and large quantities of graft can easily be provided. Within the broad ...

journal_title：Current pharmaceutical biotechnology

authors： Gotz W,Papageorgiou SN

更新日期：2017-01-01 00:00:00

abstract：:Cancer, as the most serious threat to human health, poses millions of deaths in the world each year. In vitro cancer cell and biomarker detection is of great importance for early cancer diagnosis and therapy, which needs highly sensitive, selective and quantitative diagnosis platforms. Threedimensional paper-based ele...

journal_title：Current pharmaceutical biotechnology

authors： Li Z,Hu J,Xu F,Li F

更新日期：2016-01-01 00:00:00

abstract：:Autonomic neural functions are important to regulate vital functions in the living body. There are different methods to evaluate indirectly and directly autonomic, sympathetic and parasympathetic, neural functions of human body. Among various methods, microneurography is a technique to evaluate directly sympathetic ne...

journal_title：Current pharmaceutical biotechnology

authors： Mano T

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:L2-based Human Papillomavirus (HPV) prophylactic vaccines, containing epitopes from HPV minor capsid proteins, are under investigation as second-generation HPV vaccines. No such vaccine has passed clinical trials yet, mainly due to the low immunogenicity of peptide vaccines; so efforts are being continued. A...

journal_title：Current pharmaceutical biotechnology

authors： Negahdaripour M,Nezafat N,Heidari R,Erfani N,Hajighahramani N,Ghoshoon MB,Shoolian E,Rahbar MR,Najafipour S,Dehshahri A,Morowvat MH,Ghasemi Y

更新日期：2020-01-01 00:00:00

abstract：:Natural compounds represent a significant source for the development of novel medicines. Finding the target proteins for a natural compound is the most important step towards understanding its molecular mechanism for therapeutic usage. In fact, the search for target proteins could be considered the first step of the d...

journal_title：Current pharmaceutical biotechnology

authors： Yao L

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The re-emerging of targeting Dihydroorotate Dehydrogenase (DHODH) in cancer treatment particularly Acute Myelogenous Leukemia (AML) has corroborated the substantial role of DHODH in cancer and received the attention of many pharmaceutical industries. OBJECTIVE:The effects of Brequinar Sodium (BQR) and 4SC-1...

journal_title：Current pharmaceutical biotechnology

authors： Kadir MFA,Othman S,Nellore K

更新日期：2020-01-01 00:00:00

abstract：:Control of VEGF signaling is an intense objective of pre-clinical and clinical studies in HCC disease with steadily increasing clinical application. Despite its emerging role, several aspects of anti-VEGF based treatments are poorly investigated, like the impact on tumor cells themselves, such as the effect on intrace...

journal_title：Current pharmaceutical biotechnology

authors： Raskopf E,Vogt A,Decker G,Hirt S,Daskalow K,Cramer T,Standop J,Gonzalez-Carmona MA,Sauerbruch T,Schmitz V

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The pregnancy pathology preeclampsia is still among the leading causes of maternal and perinatal morbidity and mortality. At the same time, its etiology is far from being identified and remains obscure in a number of facets. A number of hypotheses have been developed to explain the altered interplay between ...

journal_title：Current pharmaceutical biotechnology

authors： Huppertz B

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Nanotechnology involves the synthesis of materials that are in nanometre sizes (1 to 100 nm). Nanotechnology has appeared as a new area of fundamental science and is getting worldwide consideration due to its extensive applications. They have exceptional physicochemical properties due to their unique size, s...

journal_title：Current pharmaceutical biotechnology

authors： Roy A

更新日期：2020-10-27 00:00:00

abstract：:Polyphenols are a widely distributed group of natural products found in fruits, vegetables, nuts, seeds, stems and flowers. Such compounds, especially dietary flavonoids and tannins, have been shown to exert antioxidant, antiinflammatory, anti-cancer and antibacterial effects and may have beneficial effects on human h...

journal_title：Current pharmaceutical biotechnology

authors： Coppo E,Marchese A

更新日期：2014-01-01 00:00:00

abstract：:Understanding and consequently treating neuropathic pain effectively is a challenge for modern medicine, as unlike inflammation, which can be controlled relatively well, chronic pain due to nerve injury is refractory to most current therapeutics. Here we define a target pathway for a new class of analgesics, tetrahydr...

journal_title：Current pharmaceutical biotechnology

authors： Latremoliere A,Costigan M

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:The goals of this study were to observe how luteolin protects endothelial cells (ECs) from injury stimulated by Angiotensin II (Ang II), investigate the role of vascular endothelial dysfunction in vascular smooth muscle cell proliferation and migration in vitro and investigate its primary mechanism of action....

journal_title：Current pharmaceutical biotechnology

authors： Ding H,Li D,Zhang Y,Zhang T,Zhu H,Xu T,Luo Y,Wang C

更新日期：2014-01-01 00:00:00

abstract：AIMS:The present study aims to determine the antimicrobial efficacy of Alphonsea madraspatana leaves extract against selected uropathogens. BACKGROUND:The plant Alphonsea madraspatana is an endangered species, reported to exhibit high antimicrobial activity due to the presence of phenolic compounds. Prevalence of high...

journal_title：Current pharmaceutical biotechnology

authors： Sahu A,Ghosh G,Rath G

更新日期：2020-01-01 00:00:00

abstract：: ...

journal_title：Current pharmaceutical biotechnology

authors： Giaginis C

更新日期：2018-01-01 00:00:00

abstract：:Carbon monoxide (CO) has long been considered a purely toxic by-product of incomplete combustion processes. Acute exposure to high concentrations of CO is one of the leading causes of fatal poisoning in industrial countries. However, after two decades of intensive research, there is ample evidence that CO endogenously...

journal_title：Current pharmaceutical biotechnology

authors： Schmidt R,Ryan H,Hoetzel A

更新日期：2012-05-01 00:00:00

abstract：:Lipid nanocapsules with their unique composition represent a promising biocompatible drug delivery platform in nanometer range with narrow size distribution. They are highly stable in comparison to other nano-vectors and were found to impart very desirable characteristics to the therapeutic molecule being delivered wi...

journal_title：Current pharmaceutical biotechnology

authors： Nasr M,Abdel-Hamid S

更新日期：2015-01-01 00:00:00

abstract：:Fc-based therapeutics including therapeutic full-size monoclonal antibodies (mAbs) and Fcfusion proteins represent fastest-growing market in biopharmaceutical industrial. However, one major challenge during development of Fc-based therapeutics is how to maintain their efficacy in clinic use. Many factors may lead to f...

journal_title：Current pharmaceutical biotechnology

authors： Chen X,Zeng F,Huang T,Cheng L,Liu H,Gong R

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Advanced gastrointestinal stromal tumours (GISTs) are treated with tyrosine kinase inhibitors, which also have antiangiogenic properties. Dual-energy CT (DECT) allows to acquire semi-quantitative iodine images which might correlate with blood pool and tumor vascularity. In this feasibility-study, we correlated ...

journal_title：Current pharmaceutical biotechnology

authors： Schramm N,Schlemmer M,Englhart E,Hittinger M,Becker C,Reiser M,Berger F

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Large-scale population studies showed that the SNP rs1764391 of Connexin37 gene also known as Cx37 gene may play a pivotal role in the occurrence and development of acute myocardial infarction (AMI). Published results, however, are highly controversial. OBJECTIVE:This study aimed to examine the association ...

journal_title：Current pharmaceutical biotechnology

authors： Li J,Qin R,Wang W,Huang Z,Huang DL,Li T,Wang F,Zeng XT,Sun ZY,Liu XF,Huang F,Guo T

更新日期：2020-01-01 00:00:00

abstract：:After a tooth extraction both hard and soft tissues undergo dimensional changes. The use of a ridge preservation technique at the moment of the tooth extraction could help could help to prevent the volume loss, thus simplifying the subsequent prosthetic and/or implant therapy. Some studies were conducted in order to e...

journal_title：Current pharmaceutical biotechnology

authors： Alfonsi F,Borgia V,Iezzi G,Piattelli A,Covani U,Tonelli P,Barone A

更新日期：2017-01-01 00:00:00

abstract：:Signals relayed through G protein-coupled receptors (GPCR) play pivotal roles in human physiology and are important drug targets. About 40% of all GPCRs couple to the heterotrimeric G protein Gq. Biochemical studies as well as crystallography have improved our understanding of GqPCRs and their downstream partners. Her...

journal_title：Current pharmaceutical biotechnology

authors： Jalink K,Adjobo-Hermans MJ

更新日期：2014-01-01 00:00:00

abstract：:In order to valorize novel biotechnology innovations, there is a need to evaluate ex-ante their market potential. A case in point is biofortification, i.e. the enhancement of the micronutrient content of staple crops through conventional or genetic breeding techniques. In a recent article in Nature Biotechnology, for ...

journal_title：Current pharmaceutical biotechnology

authors： De Steur H,Blancquaert D,Gellynck X,Lambert W,Van Der Straeten D

更新日期：2012-12-01 00:00:00

abstract：:Tryparedoxin peroxidase (TryP) is a key enzyme of the trypanothione-dependent metabolism for removal of oxidative stress in leishmania. These enzymes function as antioxidants through their peroxidase and peroxynitrite reductase activities. Inhibitors of this enzyme are presumed to be antilesihmania drugs and structura...

journal_title：Current pharmaceutical biotechnology

authors： Singh BK,Dubey VK

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Osteosarcoma is a malignant tumor type that starts in bone and occurs most frequently in adolescents. Traditional techniques are insufficient, especially for metastatic ones. As alternative treatment techniques, natural products are worthy to examine due to being safe and innovative. Essential polyunsaturate...

journal_title：Current pharmaceutical biotechnology

authors： Sahin D

更新日期：2020-09-27 00:00:00

abstract：BACKGROUND:Sexual dysfunction and infertility are conditions with high prevalence in the general population. Nutritional factors have been reported to have an impact on sexual and reproductive health. OBJECTIVE:The aim of this review is to summarize the data on nutritional factors that have influence on male and femal...

journal_title：Current pharmaceutical biotechnology

authors： Silva T,Jesus M,Cagigal C,Silva C

更新日期：2019-01-01 00:00:00

abstract：:Ribotoxins constitute a family of toxic extracellular fungal RNases that exert a highly specific activity on a conserved region of the larger molecule of rRNA, known as the sarcin-ricin loop. This cleavage of a single phosphodiester bond inactivates the ribosome and leads to protein synthesis inhibition and cell death...

journal_title：Current pharmaceutical biotechnology

authors： Carreras-Sangrà N,Alvarez-García E,Herrero-Galán E,Tomé J,Lacadena J,Alegre-Cebollada J,Oñaderra M,Gavilanes JG,Martínez-Del-Pozo A

更新日期：2008-06-01 00:00:00

abstract：:Increasing evidence shows that the interaction between neoplastic cells and the surrounding stroma is a critical factor in solid tumor growth. The tumor stroma is made up of diverse cellular populations including macrophages, lymphocytes, vascular cells, and carcinoma-associated fibroblasts. The complex interactions b...

journal_title：Current pharmaceutical biotechnology

authors： Anton K,Glod J

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:In this study, local sustainable enzyme sources involving excised digestive juice of African land snail and yeast were utilized to achieve the simultaneous saccharification (SSF) and fermentation (SSF) of plantain pseudostem (PPS) waste, and afterwards their effects on terpenoids using gas chromatography cou...

journal_title：Current pharmaceutical biotechnology

authors： Uchenna AP,Charity ON,Abbey B

更新日期：2019-01-01 00:00:00

abstract：:CNS disorders are the third major problem of health in developed countries, with approximately 10% of direct costs associated with a pharmacological treatment of doubtful cost-effectiveness. There is an alarming abuse of psychotropic drugs worldwide and only 20-30% of patients with CNS disorders appropriately respond ...

journal_title：Current pharmaceutical biotechnology

authors： Cacabelos R,Martinez-Bouza R,Carril JC,Fernandez-Novoa L,Lombardi V,Carrera I,Corzo L,McKay A

更新日期：2012-04-01 00:00:00

abstract：:Tuberculosis (TB) is a disease of global concern. About one third of the world population is infected with Mycobacterium tuberculosis. Every year, approximately 8 million people get the disease and 2 million die of TB. The currently available vaccine against TB is the attenuated strain of Mycobacterium bovis, Bacillus...

journal_title：Current pharmaceutical biotechnology

authors： Mustafa AS

更新日期：2001-06-01 00:00:00