Abstract:
:A number of gene silencing phenomena that inactivate genes at the post-transcriptional level have been identified. Due to its potential for studying gene function, post-transcriptional gene silencing (PTGS) has become an intense area of research. In this review we describe the different means of inducing PTGS and discuss the possible biological roles of these artificially induced phenomena. We also discuss other features of PTGS such as the mechanism of mRNA degradation, the nature of the silencing signal and the mechanism of PTGS inhibition by viral proteins.
journal_name
EMBO Repjournal_title
EMBO reportsauthors
Chicas A,Macino Gdoi
10.1093/embo-reports/kve231keywords:
subject
Has Abstractpub_date
2001-11-01 00:00:00pages
992-6issue
11eissn
1469-221Xissn
1469-3178pii
2/11/992journal_volume
2pub_type
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