Pore sizes in hydrated dextran microspheres.

abstract：:Nanocellulose-based self-standing films are becoming a substrate for flexible electronics, diagnostics, and sensors. Strength and surface chemistry are vital variables for these film-based endeavors, the former is one of the assets of nanocellulose. To contribute to the latter, nanocellulose films are tuned with a sid...

journal_title：Biomacromolecules

authors： Nypelö T,Amer H,Konnerth J,Potthast A,Rosenau T

更新日期：2018-03-12 00:00:00

abstract：:Smart nanocarriers for the transport of drugs to tumor cells are nowadays of great interest for treating cancer. The use of enzymatic stimuli to cleave peptide-based drug nanocapsules for the selective release of nanocapsule cargo in close proximity to tumor cells opens new possibilities in cancer research. In the pre...

journal_title：Biomacromolecules

authors： Knaff PM,Kersten C,Willbold R,Champanhac C,Crespy D,Wittig R,Landfester K,Mailänder V

更新日期：2020-04-13 00:00:00

abstract：:Consensus motifs for sequences of both crystallizable and amorphous blocks in silks and natural structural analogues of silks vary widely. To design novel silklike polypeptides, an important question is therefore how the nature of either the crystallizable or the amorphous block affects the self-assembly and resulting...

journal_title：Biomacromolecules

authors： Willems L,van Westerveld L,Roberts S,Weitzhandler I,Calcines Cruz C,Hernandez-Garcia A,Chilkoti A,Mastrobattista E,van der Oost J,de Vries R

更新日期：2019-10-14 00:00:00

abstract：:We have found that dialysis of 5 mg/mL collagen solution into the phosphate solution with a pH of 7.1 and an ionic strength of 151 mM [corrected] at 25 °C results in a collagen gel with a birefringence and tubular pores aligned parallel to the growth direction of the gel. The time course of averaged diameter of tubula...

journal_title：Biomacromolecules

authors： Furusawa K,Sato S,Masumoto J,Hanazaki Y,Maki Y,Dobashi T,Yamamoto T,Fukui A,Sasaki N

更新日期：2012-01-09 00:00:00

abstract：:Biodegradable polyrotaxanes (PRXs) were synthesized from bis-amino-terminated poly(L-lactide) (PLLA) and alpha-cyclodextrin (alpha-CD), combined with capping by bulky end groups at the amino-termini of PLLA through enzymatically cleavable peptide linkages. The crystalline structure of the PRXs in the solid state was i...

journal_title：Biomacromolecules

authors： Ohya Y,Takamido S,Nagahama K,Ouchi T,Katoono R,Yui N

更新日期：2009-08-10 00:00:00

abstract：:Nature shows excellent control over the mechanics of fibrous hydrogels by assembling protein fibers into bundles of well-defined dimensions. Yet, obtaining artificial materials displaying controlled bundling remains a challenge. Here, we developed genetically engineered protein-based polymers functionalized with hepar...

journal_title：Biomacromolecules

authors： Włodarczyk-Biegun MK,Slingerland CJ,Werten MW,van Hees IA,de Wolf FA,de Vries R,Stuart MA,Kamperman M

更新日期：2016-06-13 00:00:00

abstract：:We demonstrate the formation of polyethylene glycol (PEG) based hydrogels via oxime ligation and the photoinitiated thiol-ene 3D patterning of peptides within the hydrogel matrix postgelation. The gelation process and final mechanical strength of the hydrogels can be tuned using pH and the catalyst concentration. The ...

journal_title：Biomacromolecules

authors： Lin F,Yu J,Tang W,Zheng J,Defante A,Guo K,Wesdemiotis C,Becker ML

更新日期：2013-10-14 00:00:00

abstract：:The calcium-binding sites of calbindin D(9k) have a helix-loop-helix motif. In this study, the helix motifs were replaced by several Ala-Gly repeating regions designed on the basis of the primary sequences of several silk fibroins. The synthesized peptides were treated with several organic solvents to modify the secon...

journal_title：Biomacromolecules

authors： Asakura T,Hamada M,Nakazawa Y,Ha SW,Knight DP

更新日期：2006-02-01 00:00:00

abstract：:Control of the photoluminescence properties of cellulose is conducted by introduction of conducting polymers including fluorene (F) and 3-hexylthiophene (3HT) on cellulose surface through FeCl3 oxidative polymerization. The UV-vis absorption peak of cellulose grafted with the 3-hexylthiophene and fluorene copolymer wa...

journal_title：Biomacromolecules

authors： Phung Hai TA,Sugimoto R

更新日期：2017-12-11 00:00:00

abstract：:Benefiting from their inherent localized and controlled release properties, hydrogels are ideal delivery systems for therapeutic drugs or nanoparticles. In particular, applications of hydrogels for the delivery and release of photoresponsive drugs or nanoparticles are receiving increasing attention. However, the effec...

journal_title：Biomacromolecules

authors： Xia LY,Zhang X,Cao M,Chen Z,Wu FG

更新日期：2017-10-09 00:00:00

abstract：:Given the significance of hydrogels as cell-instructive materials, it is important to understand how differences in their chemical and physical properties are able to direct cell fate. For example, it remains unclear how different hydrogel cross-linking chemistries and gelation mechanisms influence cell behavior. Here...

journal_title：Biomacromolecules

authors： Loebel C,Szczesny SE,Cosgrove BD,Alini M,Zenobi-Wong M,Mauck RL,Eglin D

更新日期：2017-03-13 00:00:00

abstract：:Two kinds of regioselectively substituted cellulose derivatives, i.e., 6-O-triphenylmethylcellulose (6TC) and 2,3-di-O-acetyl-6-O-triphenylmethylcellulose (2,3Ac6TC), were prepared via cellulose. In these samples, C-6 position hydroxyls in the anhydroglucose units (AGU) along the cellulose chain were selectively subst...

journal_title：Biomacromolecules

authors： Tsunashima Y,Hattori K,Kawanishi H,Horii F

更新日期：2001-10-01 00:00:00

abstract：:There is compelling evidence that, beyond their traditional role in hemostasis and thrombosis, platelets play a significant role in mediating hematologic mechanisms of tumor metastasis by directly and indirectly interacting with pro-metastatic cancer cells. With this rationale, we hypothesized that platelets can be an...

journal_title：Biomacromolecules

authors： Modery-Pawlowski CL,Master AM,Pan V,Howard GP,Sen Gupta A

更新日期：2013-03-11 00:00:00

abstract：:The effect of moisture content and temperature on water diffusion into a modified high amylose (< or = 90%) maize thermoplastic starch blend was investigated. Gravimetric and magnetic resonance imaging (MRI) studies were conducted to elucidate the diffusion mechanism and diffusion coefficients for this system. The dif...

journal_title：Biomacromolecules

authors： Russo MA,Strounina E,Waret M,Nicholson T,Truss R,Halley PJ

更新日期：2007-01-01 00:00:00

abstract：:Protein polymers (long-chain proteins in which a specific amino acid sequence "monomer" is repeated through the molecule) are found widely in nature, and these materials exhibit a diverse array of physical properties. One class of self-assembling proteins is hydrophobic-polar (HP) protein polymers capable of self-asse...

journal_title：Biomacromolecules

authors： Marner WD 2nd,Shaikh AS,Muller SJ,Keasling JD

更新日期：2008-01-01 00:00:00

abstract：:A series of well-defined thermoresponsive diblock copolymers (PEO45-b-PtNEAn, n=22, 44, 63, 91, 172) were prepared by the atom transfer radical polymerization of trans-N-(2-ethoxy-1,3-dioxan-5-yl) acrylamide (tNEA) using a poly(ethylene oxide) (PEO45) macroinitiator. All copolymers are water-soluble at low temperature...

journal_title：Biomacromolecules

authors： Qiao ZY,Ji R,Huang XN,Du FS,Zhang R,Liang DH,Li ZC

更新日期：2013-05-13 00:00:00

abstract：:In this study, generation 5 (G5) polyamidoamine (PAMAM) dendrimers with two different surface groups, G4.5-COOH and G5-OH, were investigated for their protective effects on pancreas injury in a caerulein-induced acute pancreatitis (AP) mouse model. Both dendrimers significantly decreased pathological changes in the pa...

journal_title：Biomacromolecules

authors： Tang Y,Han Y,Liu L,Shen W,Zhang H,Wang Y,Cui X,Wang Y,Liu G,Qi R

更新日期：2015-01-12 00:00:00

abstract：:Herein we report the synthesis of biodegradable hyperbranched polyglycerols (BHPGs) having acid-cleavable core structure by anionic ring-opening multibranching polymerization (ROMBP) of glycidol using initiators bearing dimethyl and cyclohexyl ketal groups. Five different multifunctional initiators carrying one to fou...

journal_title：Biomacromolecules

authors： Shenoi RA,Lai BF,Kizhakkedathu JN

更新日期：2012-10-08 00:00:00

abstract：:Biobased omega-carboxy fatty acid monomers 1,18-cis-9-octadecenedioic, 1,22-cis-9-docosenedioic, and 1,18-cis-9,10-epoxy-octadecanedioic acids were synthesized in high conversion yields from oleic, erucic and epoxy stearic acids by whole-cell biotransformations catalyzed by C. tropicalis ATCC20962. Maximum volumetric ...

journal_title：Biomacromolecules

authors： Yang Y,Lu W,Zhang X,Xie W,Cai M,Gross RA

更新日期：2010-01-11 00:00:00

abstract：:As a biomaterial, silk presents unique features with a combination of excellent mechanical properties, biocompatibility, and biodegradability. The biodegradability aspects of silk biomaterials, especially with options to control the rate from short (days) to long (years) time frames in vivo, make this protein-based bi...

journal_title：Biomacromolecules

authors： Guo C,Li C,Kaplan DL

更新日期：2020-05-11 00:00:00

abstract：:A unified kinetic pathway for the enzyme-catalyzed polymerization and degradation of poly(ε-caprolactone) was developed. This model tracks the complete distribution of individual chain lengths, both enzyme-bound and in solution, and successfully predicts monomer conversion and the molecular mass distribution as a func...

journal_title：Biomacromolecules

authors： Johnson PM,Kundu S,Beers KL

更新日期：2011-09-12 00:00:00

abstract：:Novel biodegradable poly(carbonate ester)s with photolabile protecting groups were synthesized by ring-opening copolymerization of L-lactide (LA) with 5-methyl-5-(2-nitro-benzoxycarbonyl)-1,3-dioxan-2-one (MNC) with diethyl zinc (Et2Zn) as catalyst. The poly(L-lactide-co-5-methyl-5-carboxyl-1,3-dioxan-2-one) (P(LA-co-...

journal_title：Biomacromolecules

authors： Xie Z,Hu X,Chen X,Sun J,Shi Q,Jing X

更新日期：2008-01-01 00:00:00

abstract：:RNA interference (RNAi) requires the intracellular delivery of RNA molecules to initiate the neutralization of targeted mRNA molecules, inhibiting the expression or translation of the targeted gene. Current polymers and lipids that are used to deliver RNA molecules are generally required to be positively charged, to a...

journal_title：Biomacromolecules

authors： Jiang Z,Cui W,Prasad P,Touve MA,Gianneschi NC,Mager J,Thayumanavan S

更新日期：2019-01-14 00:00:00

abstract：:Polymer therapeutics, including polymeric drugs and polymer-protein conjugates, are clinically established as first-generation nanomedicines. Knowing that the coiled-coil peptide motif is fundamentally important in the regulation of many cellular and pathological processes, the aim of these studies was to examine the ...

journal_title：Biomacromolecules

authors： Deacon SP,Apostolovic B,Carbajo RJ,Schott AK,Beck K,Vicent MJ,Pineda-Lucena A,Klok HA,Duncan R

更新日期：2011-01-10 00:00:00

abstract：:A wood based yarn platform for capturing pharmaceutical molecules from water was developed. Cellulose fiber yarns were modified with cyclodextrins, and the capture of 17α-ethinyl estradiol (EE2), a synthetic estrogen hormone used as contraceptive, from water was tested. The yarns were prepared by spinning a deep eutec...

journal_title：Biomacromolecules

authors： Orelma H,Virtanen T,Spoljaric S,Lehmonen J,Seppälä J,Rojas OJ,Harlin A

更新日期：2018-02-12 00:00:00

abstract：:In the present work, a novel synthetic methodology for the preparation of scaffold of biopolymeric nature is described. In particular, a porous gelatin scaffold was prepared by foam templating. The gas phase, nitrogen, was generated by means of the reaction between sulfamic acid and sodium nitrite in situ a concentrat...

journal_title：Biomacromolecules

authors： Barbetta A,Gumiero A,Pecci R,Bedini R,Dentini M

更新日期：2009-12-14 00:00:00

abstract：:Despite great potential, the delivery of genetic materials into cells or tissues of interest remains challenging owing to their susceptibility to nuclease degradation, lack of permeability to the cell membrane, and short in vivo half-life, which severely restrict their widespread use in therapeutics. To surmount these...

journal_title：Biomacromolecules

authors： Le TMD,Duong HTT,Thambi T,Giang Phan VH,Jeong JH,Lee DS

更新日期：2018-08-13 00:00:00

abstract：:Single-molecule total internal reflection fluorescence microscopy was used to observe the dynamic behavior of polycytosine single-stranded DNA (ssDNA) (1-50 nucleotides long) at the interface between aqueous solution and hydrophilic (oligoethylene glycol-modified fused silica, OEG) and hydrophobic (octadecyltriethoxys...

journal_title：Biomacromolecules

authors： Monserud JH,Schwartz DK

更新日期：2012-12-10 00:00:00

abstract：:The use of polyelectrolyte surface-modified Cowpea mosaic virus (CPMV) for the templated synthesis of narrowly dispersed gold nanoparticles is described. The cationic polyelectrolyte, poly(allylamine) hydrochloride (PAH), is electrostatically bound to the external surface of the virus capsid; the polyelectrolyte promo...

journal_title：Biomacromolecules

authors： Aljabali AA,Lomonossoff GP,Evans DJ

更新日期：2011-07-11 00:00:00

abstract：:An artificial spinning system using regenerated silk fibroin solutions is adopted to produce high-performance silk fibers. In previous studies, alcohol-based agents, such as methanol or ethanol, were used to coagulate silk dope solutions, producing silk fiber with poor mechanical properties compared with those of nati...

journal_title：Biomacromolecules

authors： Yazawa K,Malay AD,Ifuku N,Ishii T,Masunaga H,Hikima T,Numata K

更新日期：2018-06-11 00:00:00