Abstract:
:The global gene expression profiles for 67 human lung tumors representing 56 patients were examined by using 24,000-element cDNA microarrays. Subdivision of the tumors based on gene expression patterns faithfully recapitulated morphological classification of the tumors into squamous, large cell, small cell, and adenocarcinoma. The gene expression patterns made possible the subclassification of adenocarcinoma into subgroups that correlated with the degree of tumor differentiation as well as patient survival. Gene expression analysis thus promises to extend and refine standard pathologic analysis.
journal_name
Proc Natl Acad Sci U S Aauthors
Garber ME,Troyanskaya OG,Schluens K,Petersen S,Thaesler Z,Pacyna-Gengelbach M,van de Rijn M,Rosen GD,Perou CM,Whyte RI,Altman RB,Brown PO,Botstein D,Petersen Idoi
10.1073/pnas.241500798keywords:
subject
Has Abstractpub_date
2001-11-20 00:00:00pages
13784-9issue
24eissn
0027-8424issn
1091-6490pii
241500798journal_volume
98pub_type
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