Differential effects of the aging process on the morphology of the hypothalamic ventromedial nucleus of male and female rats.

abstract：:Noise-induced hearing loss (NIHL) has been thought to primarily involve damage to the sensory hair cells of the cochlea via mechanical and metabolic mechanisms. This study examined the effects of baicalin, baicalein, and Scutellaria baicalensis (SB) extract against NIHL in a mouse model. Mice received oral treatment w...

journal_title：Neuroscience letters

authors： Kang TH,Hong BN,Park C,Kim SY,Park R

更新日期：2010-01-29 00:00:00

abstract：:In previous studies, chronic low-dose methylphenidate (MPH) administration during early development has been shown to increase emotional responding in adulthood. However, most studies employed male subjects, which generally show enhanced fear relative to females in laboratory tests of anxious behaviors. The present st...

journal_title：Neuroscience letters

authors： Bethancourt JA,Vásquez CE,Britton GB

更新日期：2011-05-27 00:00:00

abstract：:Cold defense mechanisms in mice are attenuated in the light phase during fasting, resulting in hypothermia. The present study examined whether specific neurons and areas in the SCN are related to the response. Mice were fasted over 47h or remained fed, during which they were placed at 20 or 27°C for 3h in the light or...

journal_title：Neuroscience letters

authors： Uchida Y,Tokizawa K,Nagashima K

更新日期：2014-09-05 00:00:00

abstract：:Exposure of rat hippocampal neurons to the peptide amyloid beta (A beta) (25-35) as well as A beta (1-40) peptides enhances phosphorylation of tau to a paired helical filament (PHF)-state through activation of tau protein kinase I (TPK I)/glycogen synthase kinase-3 beta (GSK-3 beta) [Busciglio, J., Lorenzo, A., Yeh, J...

journal_title：Neuroscience letters

authors： Takashima A,Noguchi K,Michel G,Mercken M,Hoshi M,Ishiguro K,Imahori K

更新日期：1996-01-12 00:00:00

abstract：:Central serotonergic neurotransmission has been implicated in the aetiology of ethanol tolerance and dependence. Cellular expression of the serotonin transporter and serotonin reuptake is modulated via a polymorphic, repetitive element in the 5'-flanking regulatory region of the serotonin transporter gene (5-HTTLPR). ...

journal_title：Neuroscience letters

authors： Türker T,Sodmann R,Goebel U,Jatzke S,Knapp M,Lesch KP,Schuster R,Schütz H,Weiler G,Stöber G

更新日期：1998-06-05 00:00:00

abstract：:The localization of serotonin and non-serotonin-containing cell bodies in the interpeduncular nucleus of the rat that project to the hippocampal formation was studied using the technique of retrograde tracing of Granular Blue and immunohistochemistry on the same sections. The results indicate that the caudal magnocell...

journal_title：Neuroscience letters

authors： Groenewegen HJ,Steinbusch HW

更新日期：1984-09-28 00:00:00

abstract：:We investigate the relationship between visually induced perceptual illusions of body motion (vection) and visually induced postural responses (VEPRs). Ten standing healthy subjects were tested in two visual conditions known to induce directionally opposite VEPRs: subjects fixated either a static head-mounted or an ea...

journal_title：Neuroscience letters

authors： Guerraz M,Bronstein AM

更新日期：2008-09-26 00:00:00

abstract：:We report a sporadic case of tauopathy with unusual clinical and neuropathological features. The patient presented with progressive symmetric rigid-akinetic parkinsonism and dementia of the subcortical type. Magnetic resonance imaging of the brain revealed atrophy resembling multiple system atrophy. The level of cereb...

journal_title：Neuroscience letters

authors： Ohara S,Tsuyuzaki J,Oide T,Arai H,Higuchi S,Hasegawa M,Iwatsubo T

更新日期：2002-09-13 00:00:00

abstract：:Alzheimer's disease (AD) brains contain high levels of advanced glycation endproducts (AGEs). Double immunostaining using anti-AGE and anti-apolipoprotein E (apoE) antibodies demonstrated that AGEs co-localized to a very high degree with apoE. We examined the binding of apoE to in vitro-prepared AGE-bovine serum album...

journal_title：Neuroscience letters

authors： Li YM,Dickson DW

更新日期：1997-05-02 00:00:00

abstract：:Cancer patients with bone metastases often suffer breakthrough pain. However, little progress has been made in the treatment of breakthrough pain and its associated mechanism(s) in the patient with cancer due to lacking of resembling and predictive animal models. We previously have demonstrated that endothelin-1 plays...

journal_title：Neuroscience letters

authors： Tang Y,Peng H,Liao Q,Gan L,Zhang R,Huang L,Ding Z,Yang H,Yan X,Gu Y,Zang X,Huang D,Cao S

更新日期：2016-03-23 00:00:00

abstract：:Nicotine is known to stimulate energy expenditure, although the precise mechanism is unclear. To clarify the involvement of corticotropin-releasing factor (CRF) in the mechanism by which nicotine increases energy expenditure, the effect of intraperitoneal injection of nicotine (0.1 or 0.5mg/kg) on the release of norad...

journal_title：Neuroscience letters

authors： Mano-Otagiri A,Iwasaki-Sekino A,Ohata H,Arai K,Shibasaki T

更新日期：2009-05-08 00:00:00

abstract：:A series of experiments were designed to examine the potential induction of apoptosis by nitric oxide (NO) donors on cortical neuronal cell culture. A 24 h exposure of three different NO donors, 3-morpholinosydnonimine, S-nitroso-N-acetyl-penicillamine, and S-nitrosoglutathione, induced apoptosis as indicated by follo...

journal_title：Neuroscience letters

authors： Palluy O,Rigaud M

更新日期：1996-04-12 00:00:00

abstract：:Prolactin (PRL) has been shown to be altered by psychotropic drugs, including antidepressant drugs (ADs). Many studies have focused on the response to antidepressant treatment (especially related to the serotonergic system) using the fenfluramine test (PRF), however some data suggest lack of correlation between PRF an...

journal_title：Neuroscience letters

authors： Faron-Górecka A,Kuśmider M,Szafran-Pilch K,Kolasa M,Żurawek D,Gruca P,Papp M,Solich J,Pabian P,Dziedzicka-Wasylewska M

更新日期：2017-04-24 00:00:00

abstract：:Recent studies suggested that statins have anti-inflammatory effects beyond their lipid-lowering properties. In the present study, we sought to investigate whether rosuvastatin could alleviate morphine tolerance by attenuating the glia mediated neuroinflammation in the spinal cord. Using a rat model of L5 spinal nerve...

journal_title：Neuroscience letters

authors： Li W,Li Y,Zhu S,Ji Q,Shu Y,Zhang L,Liu J

更新日期：2015-01-01 00:00:00

abstract：:A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes. Complement activation is one of the cardinal pathological features of the inflammation. Intensive AD association studies investigating polymorphisms in inflammatory-related genes have been recently perfor...

journal_title：Neuroscience letters

authors： Rosenmann H,Meiner Z,Kahana E,Aladjem Z,Friedman G,Ben-Yehuda A,Grenader T,Wertman E,Abramsky O

更新日期：2003-01-16 00:00:00

abstract：:The 5-HT(1A) receptor agonist 8-OH-DPAT (0.5mg/kg) enhances behavioral recovery when administered 15min after experimental traumatic brain injury (TBI). To determine if benefits are still attainable at clinically relevant times, treatment was delayed 1 and 2h post-TBI and motor/cognitive performance was compared to ea...

journal_title：Neuroscience letters

authors： Cheng JP,Aslam HA,Hoffman AN,Zafonte RD,Kline AE

更新日期：2007-04-12 00:00:00

abstract：:We have investigated the presence of mutations in the parkin gene in patients with early-onset parkinsonism. Direct sequencing of the polymerase chain reaction (PCR) products showed a homozygous G deletion in the exon 7 (c.871delG) in one patient. This was a 38-year-old Moroccan woman with a history of parkinsonism of...

journal_title：Neuroscience letters

authors： Muñoz E,Pastor P,Martí MJ,Oliva R,Tolosa E

更新日期：2000-07-28 00:00:00

abstract：:The association between the dopamine D4 receptor (DRD4) exon III polymorphism and personality trait of novelty seeking (NS) has been studied intensively. In the Japanese population, the results of the previous studies did not always coincide. In the present study, we investigated the association between the polymorphi...

journal_title：Neuroscience letters

authors： Tochigi M,Hibino H,Otowa T,Kato C,Marui T,Ohtani T,Umekage T,Kato N,Sasaki T

更新日期：2006-05-08 00:00:00

abstract：:The specific mRNA of myelin basic protein (MBP) was isolated from active myelinating rat brains. The isolated mRNA was able to direct the synthesis of immunochemically detectable MBP in a wheat-germ cell free protein synthesis system. There was, however, no evidence of neuronal translational control of the in vitro MB...

journal_title：Neuroscience letters

authors： Fan K

更新日期：1982-03-17 00:00:00

abstract：:Brain edema is among the major complications in children with bacterial meningitis. Aquaporins are integral membrane pore proteins that form channels to regulate cellular water content. Aquaporin-4 (AQP4), which is enriched in parts of astrocytic membranes that are apposed to pial or perivascular basal laminae, is the...

journal_title：Neuroscience letters

authors： Huang J,Lu WT,Sun SQ,Yang ZB,Huang SQ,Gan SW,Xu J,Qiu GP,Zhuo F,Zhu SJ,Jiang J,Jiang XL

更新日期：2014-04-30 00:00:00

abstract：:The dorsal margin of the trigeminal principal nucleus (PV) contains neurons responsive to innocuous thermal stimulation of the tongue and maybe a thermal relay (Hayama and Hashimoto, 2011). The present electrophysiological study examined whether PV thermoreceptive neurons project to the thalamus and investigated respo...

journal_title：Neuroscience letters

authors： Hayama T

更新日期：2014-04-03 00:00:00

abstract：:The mechanisms underlying aggregate formation in age-related neurodegenerative diseases remain not well understood. Here we investigated whether dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A (Dyrk1A) is involved in the formation of regulator of calcineurin 1 (RCAN1) aggregates. We show that RCAN1 s...

journal_title：Neuroscience letters

authors： Song WJ,Song EA,Choi SH,Baik HH,Jin BK,Kim JH,Chung SH

更新日期：2013-10-25 00:00:00

abstract：:Ferumoxytol is an ultrasmall superparamagnetic iron oxide (USPIO) nanoparticle that is FDA-approved as an intravenous iron replacement therapy for the treatment of iron deficiency anemia in patients with chronic kidney disease. Ferumoxytol has also been used as a contrast agent for cerebral blood volume mapping by mag...

journal_title：Neuroscience letters

authors： Doyle KP,Quach LN,Arceuil HE,Buckwalter MS

更新日期：2015-01-01 00:00:00

abstract：:Fetal intrauterine growth restriction generates chronic hypoxia due to placental insufficiency. Despite the hemodynamic process of blood flow, redistributions are taking place in key organs such as the fetal brain during intrauterine growth restriction, in order to maintain oxygen and nutrients supply. The risk of sho...

journal_title：Neuroscience letters

authors： Hernández-Andrade E,Cortés-Camberos AJ,Díaz NF,Flores-Herrera H,García-López G,González-Jiménez M,Santamaría A,Molina-Hernández A

更新日期：2015-01-01 00:00:00

abstract：:Those with high baseline stress levels are more likely to develop mild cognitive impairment (MCI) and Alzheimer's Disease (AD). While meditation may reduce stress and alter the hippocampus and default mode network (DMN), little is known about its impact in these populations. Our objective was to conduct a "proof of co...

journal_title：Neuroscience letters

authors： Wells RE,Yeh GY,Kerr CE,Wolkin J,Davis RB,Tan Y,Spaeth R,Wall RB,Walsh J,Kaptchuk TJ,Press D,Phillips RS,Kong J

更新日期：2013-11-27 00:00:00

abstract：:Different responses evoked by stimulation of contralateral hippocampus at various levels are examined in new-born rabbits up to 1 month of age. Commissural fibres coming from the CA3-CA4 reach the contralateral regio superior (CA1) essentially at the st. oriens levels. CA1 responses elicited by stimulation of the cont...

journal_title：Neuroscience letters

authors： Thomson MA

更新日期：1979-02-01 00:00:00

abstract：:Bone mesenchymal stem cells (BMSCs) are an attractive donor graft source because of the potential of self-renewal and multi-direction differentiation. However, it is a great challenge to induce BMSCs to specifically differentiate to dopamine (DA) neurons for the treatment of Parkinson's disease. Because the striatum i...

journal_title：Neuroscience letters

authors： Yang S,Gao Q,Bao L,Zhang J,Hu Y,Bing L,Sun J,Hao J,Chen C,Li S,Poon WS,Sun J,Gao Y

更新日期：2012-11-21 00:00:00

abstract：:The three tracers horseradish peroxidase (HRP), 4',6-diamidino-2-phenylindol-2HCl (DAPI) and Fast Blue (FB) differ in retrograde labeling of striato-nigral neurons. After a 24 h survival, injection of DAPI into the ventral tegmentum labeled numerous cells throughout the neostriatum, whereas an identical amount of HRP ...

journal_title：Neuroscience letters

authors： Frotscher M,Wagner A,Misgeld U

更新日期：1983-07-29 00:00:00

abstract：:Substantial evidence supports the hypothesis that oxygen free radicals are involved in various neurodegenerative disorders. To assess the presence of oxidative stress in Alzheimer's disease (AD) we examined the activity of the enzyme copper-zinc superoxide dismutase (CuZnSOD) in red blood cells, the levels of the mito...

journal_title：Neuroscience letters

authors： De Leo ME,Borrello S,Passantino M,Palazzotti B,Mordente A,Daniele A,Filippini V,Galeotti T,Masullo C

更新日期：1998-07-10 00:00:00

abstract：:The involvement of glutamate receptors in the central transmission of somatosympathetic reflexes was studied by examining, in anesthetized rats, the effects of MK-801, an N-methyl-D-aspartate (NMDA) receptor antagonist, and CNQX, a non-NMDA receptor antagonist, on two reflex components, the A- and C-reflexes evoked in...

journal_title：Neuroscience letters

authors： Nagata O,Li WM,Sato A

更新日期：1995-12-08 00:00:00