Deamidation of human proteins.

Abstract:

:Deamidation of asparaginyl and glutaminyl residues causes time-dependent changes in charge and conformation of peptides and proteins. Quantitative and experimentally verified predictive calculations of the deamidation rates of 1,371 asparaginyl residues in a representative collection of 126 human proteins have been performed. These rates suggest that deamidation is a biologically relevant phenomenon in a remarkably large percentage of human proteins.

authors

Robinson NE,Robinson AB

doi

10.1073/pnas.221463198

keywords:

subject

Has Abstract

pub_date

2001-10-23 00:00:00

pages

12409-13

issue

22

eissn

0027-8424

issn

1091-6490

pii

221463198

journal_volume

98

pub_type

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