Abstract:
:Most patients with the Mustard procedure are now adults. To date, however, there have been few reports on resting and exercise hemodynamics in a large population of adults with this circulation. The aim of this study is to describe such parameters in one of the largest and oldest populations of adults with the Mustard procedure. The database of the University of Toronto Congenital Cardiac Centre for Adults was examined to identify 84 adults with the Mustard procedure who have undergone cardiopulmonary exercise tests. Magnetic resonance imaging and echocardiography studies were obtained in order to assess right ventricular size, function and baseline hemodynamics. Patients achieved lower maximum uptake of oxygen, maximal heart rate, forced vital capacity, forced expiratory volume in 1 second, and oxygen saturations at maximal exercise compared to a healthy population. Magnetic resonance imaging showed significantly different right ventricular ejection fractions between patients and controls. There were no effects of operative variables or preoperative hemodynamics on current exercise capacity. Patients after the Mustard procedure have subnormal exercise capacities. Factors such as chronotropic incompetence, peripheral deconditioning, and impaired lung function may be responsible for these results.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Hechter SJ,Webb G,Fredriksen PM,Benson L,Merchant N,Freeman M,Veldtman G,Warsi MA,Siu S,Liu Pdoi
10.1017/s104795110100052xkeywords:
subject
Has Abstractpub_date
2001-07-01 00:00:00pages
407-14issue
4eissn
1047-9511issn
1467-1107journal_volume
11pub_type
杂志文章abstract::Congenitally corrected transposition is a rare congenital anomaly, with only a few cases diagnosed and reported prenatally even in the largest fetal series. To determine the morphologic features and outcome for the lesion as recognized during fetal life, we reviewed the fetal and postnatal echocardiograms and medical ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795110400304X
更新日期:2004-06-01 00:00:00
abstract::Congenital stenosis of the pulmonary veins is a rare condition whose outcome is guarded despite the available treatment options. We report a case of a 6-month-old infant with significant stenosis of all four pulmonary veins. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119000428
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:It is accepted treatment to give vasopressin to adults in postcardiotomy shock, but such use in children is controversial. Cardiopulmonary bypass is presumed to attenuate the normal endogenous vasopressin response to shock. We hypothesized that levels of vasopressin in children are altered by bypass, and tha...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951108001881
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:This study evaluated the effectiveness of long-term intensive lipid-lowering therapy in children and adolescents with familial hypercholesterolaemia. METHODS:The charts of 89 children and adolescents with heterozygous familial hypercholesterolaemia among ∼1000 patients treated from 1974 to 2008 were reviewe...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113000528
更新日期:2014-06-01 00:00:00
abstract:INTRODUCTION:Stenosis, mediated by neointimal hyperplasia and thrombosis, is a major limiting factor in successful stent implantation. The introduction of a stent, coated in its endoluminal surface by antihuman CD34 antibodies with endothelial progenitor cell-capturing properties, opens the possibility of promoting a r...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113001376
更新日期:2014-10-01 00:00:00
abstract::Milrinone is a drug frequently used for hemodynamic support in children during critical illness. Although the hemodynamic changes induced by milrinone in children may appear similar to those of adults, the physiologic contributors of these changes remain vastly unknown. A systematic review was conducted to identify st...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119002865
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine developmental enamel defects and dental treatment conditions in children with congenital heart disease by comparing them with a control group of healthy children. METHODS:Children included in the study were referred to a paediatric dentistry for dental examination and t...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113002308
更新日期:2015-02-01 00:00:00
abstract::Anomalous origin of the right coronary artery from the posterior, non-coronary sinus is extremely rare and has never been reported in a paediatric-age competitive athlete. We report this very rare case of the right coronary artery arising from the posterior sinus. In the anomalous right coronary from the posterior sin...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114001346
更新日期:2015-06-01 00:00:00
abstract::Neonatal aortic thrombosis is a rare occurrence but can be life-threatening. Most aortic thrombosis in neonates is related to umbilical artery catheters. A case of a neonate with a spontaneous aortic thrombosis is described here along with a comprehensive review of the literature for cases of neonatal aortic thrombosi...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951119003093
更新日期:2020-01-01 00:00:00
abstract::The recommendations of the Association for European Paediatric and Congenital Cardiology for basic training in paediatric and congenital cardiology required to be recognised as a paediatric cardiologist by the Association for European Paediatric and Congenital Cardiology are described below. Those wishing to achieve m...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120003455
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to see whether the open anastomosis technique using vacuum-assisted venous drainage at the time of the Fontan procedure was associated with decreased post-operative pleural effusion. METHODS:We analysed a subgroup of patients with a functional single ventricle who underwent non-fen...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001010
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:The purpose of our study was to assess the prevalence and progression, during childhood and adolescence, of dilation of the neo-aortic root, and neo-aortic valvar regurgitation, and to identify risk factors for such dilation and regurgitation, after the arterial switch operation. METHODS:We included all pat...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951106000953
更新日期:2006-10-01 00:00:00
abstract::Acute myocardial infarction is rarely reported in children. Most of the cases are secondary to congenital anomalies or Kawasaki disease. Coronary artery total occlusion caused by fibromuscular dysplasia has never been reported in young children. Here we report a case of a 12-year-old boy with fibromuscular dysplasia, ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113002394
更新日期:2015-01-01 00:00:00
abstract::A bicuspid aortic valve is not only a common congenital heart defect but also an enigmatic condition that can cause a large spectrum of diseases, such as aortic valve stenosis and severe heart failure in newborns whereas aortic dissection in adults. On the contrary, a bicuspid aortic valve can also occur with normal f...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951118001658
更新日期:2019-01-01 00:00:00
abstract::A non-dysmorphic 10 month old female was discovered at surgery to have severe vasculopathy of both the systemic and pulmonary arteries. These findings were confirmed by pathologic examination. Follow-up angiography has confirmed multiple sites of vascular obstruction which appear to be worsening. Angioplasty has only ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s104795110200063x
更新日期:2002-05-01 00:00:00
abstract::In many parts of the world, mostly low- and middle-income countries, timely diagnosis and repair of congenital heart diseases (CHDs) is not feasible for a variety of reasons. In these regions, economic growth has enabled the development of cardiac units that manage patients with CHD presenting later than would be idea...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951117002591
更新日期:2017-12-01 00:00:00
abstract::Pneumopericardium, defined as air in the pericardial cavity, is a rare condition with potentially severe complications and mortality. In the neonatal period, pneumopericardium is associated with prematurity, very low birth weight, and assisted ventilation. We report the occurrence of spontaneous pneumopericardium in a...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117002657
更新日期:2018-03-01 00:00:00
abstract::Partially anomalous pulmonary venous connection of a solitary pulmonary vein in the setting of an intact atrial septum is often subclinical, and the indications for surgical repair are controversial. Here we describe a patient who developed a significant shunt over a period of 10-years. Flow through the anomalously co...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795110700159X
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Right heart function is an important predictor of morbidity and mortality in pulmonary arterial hypertension and many CHD. We investigated whether treatment with the prostacyclin analogue treprostinil could prevent pressure overload-induced right ventricular hypertrophy and failure. METHODS:Male Wistar rats...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116000160
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Anomalous left coronary artery from the pulmonary artery is a rare congenital heart disease (CHD) with diverse clinical presentations despite the same anatomy. Factors determining this heterogeneous presentation are not well understood. METHOD AND RESULTS:We retrospectively investigated 14 patients (12 fema...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119003299
更新日期:2020-03-01 00:00:00
abstract::We present a rare case of incidentally diagnosed Twiddler's syndrome in a child 7 years after implantation of a dual-chamber pacemaker system with epicardial leads. During revision, an insulation defect of the ventricular lead was evident, despite unremarkable prior pacemaker lead testing. The lead was repaired and a ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120001031
更新日期:2020-06-01 00:00:00
abstract::Interest in brain natriuretic peptide (BNP) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in the management of children with CHD has increased. There are, however, no current guidelines for their routine use. The aim of this review article is to provide an update on the data regarding the use of BNP/NT-proB...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951114002133
更新日期:2015-03-01 00:00:00
abstract::Anomalous origin of a coronary artery from the aorta is a potentially serious anomaly that occurs in about 0.1-0.2% of the population. This percentage is small; however, it translates into about 4000 annual births with these anomalies. The clinical presentation of these anomalies is rare, and hence most are and will r...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951114000250
更新日期:2014-10-01 00:00:00
abstract::Transcatheter pulmonary valve replacement is fast becoming an accepted alternative to repeat surgical pulmonary valve replacement for selected patients and therefore a complementary strategy in the long-term management of those requiring surgical pulmonary valve replacement. With a combined surgical and percutaneous a...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951112001527
更新日期:2012-12-01 00:00:00
abstract::Persistent fifth - double-lumen - aortic arch is a rarely seen entity, which is usually associated with other cardiac anomalies; it has been previously reported only in children. We report a new case of double-lumen aortic arch with a systemic-to-systemic connection diagnosed incidentally during cardiac multi-detector...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001855
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:The concept of self-management of oral anticoagulation has been shown to entail better quality of treatment than conventional management when assessed in selected adults. We have extended the concept of self-management to include children with congenital cardiac disease, hypothesizing self-management of oral ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951101000282
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to detect structural and functional changes in the left and right ventricles in obese Egyptian adolescents. Methods and results Anthropometric and echocardiographic parameters, including tissue Doppler imaging, were obtained from 70 obese adolescents with average body mass inde...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001910
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:CHD is the leading cause of mortality due to birth defects. Array comparative genomic hybridisation (aCGH) detects submicroscopic copy number changes and may improve identification of the genetic basis of CHD. METHODS:This is a retrospective analysis of 1252 patients from a regional referral centre who had ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114001838
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Neonates and infants with congenital and acquired cardiac disease often require placement of central venous lines for extended intravenous therapy. It may be advantageous to avoid the larger venous vessels of the head and neck and lower extremities in order to preserve these for future interventions and ther...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110000090
更新日期:2010-06-01 00:00:00
abstract::The interest of professional medical societies in research about outcomes, mixed with the recent accessibility to management of data on the internet, has moved many societies to create national databases or registries for their specialty. In societies with procedure-based specialties such as surgery, these databases w...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951108002916
更新日期:2008-12-01 00:00:00