Abstract:
:We compared the results of intracytoplasmic sperm injection (ICSI) that leads to full term development of hybrid (B6C3F1 and B6D2F1) and inbred (C57BL/6) mouse embryos. Although fertilization and pre-implantation development of C57BL/6 eggs were similar to those of F1 hybrid eggs, post-implantation development of the embryos from C57BL/6 females was significantly poorer than those of the eggs from hybrid females. Reciprocal crosses of C57BL/6 and B6C3F1 gametes revealed that the low rate of post-implantation development of C57BL/6 embryos was due to oocyte factor(s), rather than the sperm factor.
journal_name
Mol Reprod Devjournal_title
Molecular reproduction and developmentauthors
Kawase Y,Iwata T,Toyoda Y,Wakayama T,Yanagimachi R,Suzuki Hdoi
10.1002/mrd.1063keywords:
subject
Has Abstractpub_date
2001-09-01 00:00:00pages
74-8issue
1eissn
1040-452Xissn
1098-2795pii
10.1002/mrd.1063journal_volume
60pub_type
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