Abstract：
:For a variety of medical conditions and procedures, a higher volume-better outcome relationship has been hypothesized for over 25 years. An extensive, consistent body of literature supports a relationship between hospital volume and short-term outcomes for cancers treated with technologically complex surgical procedures. For cancer primarily treated by low-risk surgery, there are few studies. Recent studies found a modest (about 2%) difference in survival benefit between high-volume and low-volume providers associated with colon cancer surgery. Few evaluations in the last 15 years have addressed nonsurgical cancers, eg, lymphomas and testicular cancer. No reports have addressed recurrent or metastatic cancer. Care is better at high-volume providers for a select minority of cancers. Whether provider volume matters in the majority of cancers at the time of presentation has not been evaluated.
journal_name
Curr Oncol Repjournal_title
Current oncology reportsauthors
Hillner BEdoi
10.1007/s11912-001-0026-3keywords:
subject
Has Abstractpub_date
2001-09-01 00:00:00pages
404-9issue
5eissn
1523-3790issn
1534-6269journal_volume
3pub_type
杂志文章,评审abstract：:Vascular endothelial growth factor (VEGF) is the term used for a family of tumor-derived angiogenic factors that mediate endothelial proliferation and vascular permeability. Preclinical models have demonstrated the essential nature of VEGF in the angiogenesis of solid tumor growth and metastasis, whereas pathologic in...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2002-01-01 00:00:00
abstract：PURPOSE OF REVIEW:Pancreatic adenocarcinoma is a leading cause of cancer mortality in western countries with a uniformly poor prognosis. Unfortunately, there has been little in the way of novel therapeutics for this malignancy over the last several decades. Derangements in metabolic circuitry favoring excess glycolysis...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-018-0699-5
更新日期：2018-05-11 00:00:00
abstract：:The success of the angiogenesis inhibitor bevacizumab, the vascular endothelial growth factor antagonist that was recently shown to significantly improve the survival of patients with metastatic colon cancer when administered in combination with conventional chemotherapy, has provided proof of principle in clinical tr...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2004-01-01 00:00:00
abstract：PURPOSE OF REVIEW:Medical decisions concerning active surveillance are complex, especially when evidence on superiority of one of the treatments is lacking. Decision aids have been developed to facilitate shared decision-making on whether to pursue an active surveillance strategy. However, it is unclear how these decis...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-020-00962-3
更新日期：2020-07-28 00:00:00
abstract：PURPOSE OF REVIEW:Standard treatment for early-stage squamous cell cancer of the anal canal (SCCA) includes concurrent chemotherapy and radiation to achieve curative intent. Treatment options are limited, however, especially with locoregional disease relapse occurring in 20-30% of patients and about 10-30% of patients ...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-020-00946-3
更新日期：2020-07-11 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-017-0640-3
更新日期：2017-11-06 00:00:00
abstract：:The therapeutic landscape for renal cell carcinoma (RCC) has changed drastically over the past several years with the emergence of molecularly targeted therapies. With previous prognostic and predictive tools based on studies of patients treated with cytokine therapies, confirmation of these prior methods and discover...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-009-0015-5
更新日期：2009-03-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-013-0361-1
更新日期：2014-01-01 00:00:00
abstract：:Neuroblastoma is the most common extracranial tumor of childhood, with about 650 new cases each year in the United States. The clinical course of neuroblastoma is variable and depends on age at diagnosis, staging, histology, and specific genetic abnormalities, such as MYCN oncogene amplification or aberrations of chro...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-009-0059-6
更新日期：2009-11-01 00:00:00
abstract：:There has been much development in the field of targeted therapy for melanoma stemming from efforts to decrease treatment-related toxicities and enhance specific cytotoxicity. This review focuses on three modalities of targeted melanoma therapy based on the biology of the targeting mechanism. The first of these modali...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-001-0088-2
更新日期：2001-07-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2004-09-01 00:00:00
abstract：PURPOSE OF REVIEW:Opioids are the only class of drug with the proven ability to control severe pain. The introduction of stringent opioid prescribing restrictions has inevitably impacted upon the ability of those prescribing opioids for advanced life-limited disease to practice as previously and could limit the supply ...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-020-0900-5
更新日期：2020-03-13 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-006-0036-2
更新日期：2006-07-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-007-0071-7
更新日期：2007-11-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,收录出版,评审
doi：10.1007/s11912-005-0054-5
更新日期：2005-07-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-020-00923-w
更新日期：2020-06-20 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-008-0025-8
更新日期：2008-03-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-020-00949-0
更新日期：2020-07-09 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章
doi：10.1007/s11912-012-0271-7
更新日期：2012-12-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2000-07-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2017-08-12 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2007-07-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2009-09-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
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更新日期：2003-07-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-020-00951-6
更新日期：2020-07-10 00:00:00
abstract：:The introduction of targeted therapies, specifically those that target the VEGF receptor (VEGFR), PDGF receptor (PDGFR) and the mTOR pathways, has significantly changed the approach to patients with unresectable renal cell cancer (RCC). However, drug resistance develops through bypassing of targeted pathways. Regorafe...
journal_title：Current oncology reports
pub_type： 杂志文章
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更新日期：2013-04-01 00:00:00
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journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-018-0698-6
更新日期：2018-05-04 00:00:00
abstract：:The diagnosis of a gynecological malignancy during pregnancy is rare but not uncommon. Cancer treatment during pregnancy is possible, but both maternal and fetal interests need to be respected. Different treatment plans may be justifiable and multidisciplinary treatment is advised. Clinical trials are virtually imposs...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-014-0415-z
更新日期：2014-12-01 00:00:00
abstract：:Soft tissue sarcomas (STS) consist of a heterogeneous group of rare malignancies arising from mesenchymal origin. While surgical resection is the primary treatment for STS, the use of radiotherapy (RT) as an adjunctive modality has been shown to improve oncologic outcomes. Technologic improvements, such as image guida...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-016-0523-z
更新日期：2016-06-01 00:00:00
abstract：:Treatment with cytotoxic chemotherapy and radiotherapy is associated with significant gonadal damage in men and women. The likelihood of gonadal failure following cytotoxic chemotherapy is dependent on the drug and dose, and in women there is also an effect of age at treatment. Irradiation of the testes or ovaries, ei...
journal_title：Current oncology reports
pub_type： 杂志文章,评审
doi：10.1007/s11912-002-0039-6
更新日期：2002-09-01 00:00:00
