Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.

Abstract:

:The purpose of this prospective, double-blind, randomized study was to evaluate pain reduction using an intraosseous injection of slow-releasing methylprednisolone in teeth with irreversible pulpitis. Forty subjects presenting for emergency treatment completed the study. Each subject had a tooth with a clinical diagnosis of irreversible pulpitis with actively associated moderate to severe pain. After local anesthesia was attained, the subjects were randomly assigned to receive an intraosseous injection of either 1.0 ml of Depo-Medrol (40 mg) or 1.0 ml of sterile saline (control). No endodontic therapy was begun at the initial appointment. The subjects received ibuprofen and Tylenol #3 and completed a 7-day questionnaire on pain, percussion pain, and analgesic medications taken each day. Over the 7-day observation period, the subjects who received the intraosseous injection of Depo-Medrol reported significantly (p < 0.05) less pain and percussion pain while taking significantly (p < 0.05) fewer pain medications. Clinically the intraosseous injection of Depo-Medrol could be used to temporarily alleviate the symptoms of irreversible pulpitis until definitive treatment can be rendered.

journal_name

J Endod

journal_title

Journal of endodontics

authors

Gallatin E,Reader A,Nist R,Beck M

doi

10.1097/00004770-200011000-00001

keywords:

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

633-8

issue

11

eissn

0099-2399

issn

1878-3554

pii

S0099-2399(05)60805-9

journal_volume

26

pub_type

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