Abstract:
:A 44-year-old patient died from amyotrophic lateral sclerosis (ALS) after nine years of heavy exposure to cadmium (Cd) in a nickel cadmium (Ni-Cd) battery factory. Two years after starting work he and co-workers had experienced pruritus, loss of smell, nasal congestion, nosebleeds, cough, shortness of breath, severe headaches, bone pain, and proteinuria. Upper back pain and muscle weakness progressed to flaccid paralysis. EMG findings were consistent with motor neuron disease. Cd impairs the blood-brain barrier, reduces levels of brain copper-zinc (Cu-Zn) superoxide dismutase (SOD), and enhances excitoxicity of glutamate via up-regulation of glutamate dehydrogenase and down-regulation of glutamate uptake in glial cells. High levels of methallothionein, a sign of exposure to heavy metals, have been found in brain tissue of deceased ALS patients. The effects of Cd on enzyme systems that mediate neurotoxicity and motor neuron disease suggest a cause effect relationship between Cd and ALS in this worker.
journal_name
Int J Occup Environ Healthauthors
Bar-Sela S,Reingold S,Richter EDdoi
10.1179/107735201800339470keywords:
subject
Has Abstractpub_date
2001-04-01 00:00:00pages
109-12issue
2eissn
1077-3525issn
2049-3967journal_volume
7pub_type
杂志文章abstract::In the agroexport zone of Los Santos Zone in Costa Rica, coffee is harvested by migrant labor. Most migrants are from Panama and Nicaragua. We describe migrants' housing- and service-related health determinants, with analyses of ethnicity, nationality and geography. We used interviews, observation-based assessments, a...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2008.14.2.129
更新日期:2008-04-01 00:00:00
abstract:INTRODUCTION:This study on workplace injuries and risk reduction practices was part of the Malaysia National Health Morbidity Survey III (NHMS III) conducted in 2006. METHODS:This cross-sectional population-based survey was conducted to determine the incidence of workplaces injuries and assess the magnitude of some i...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/1077352512Z.00000000035
更新日期:2012-10-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章,评审
doi:10.1179/oeh.1998.4.3.189
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:Sea lampreys are parasitic fish found in lakes of the United States and Canada. Sea lamprey is controlled through manual application of the pesticides 3-trifluoromethyl-4-nitrophenol (TFM) and Bayluscide(TM) into streams and tributaries. 3-Trifluoromethyl-4-nitrophenol may cause irritation and central nervou...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/2049396715Y.0000000002
更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1179/oeh.1995.1.4.315
更新日期:1995-10-01 00:00:00
abstract::Respiratory and allergic symptoms were evaluated in 66 Iranian carpet weavers and 66 controls with similar age and gender characteristics using a questionnaire including questions on work-related respiratory symptoms in the past year, allergies, smoking habits, and work exposure duration. A total of 28 carpet weavers ...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2007.13.4.369
更新日期:2007-10-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/1077352512Z.00000000012
更新日期:2012-04-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章,评审
doi:10.1179/oeh.1998.4.4.217
更新日期:1998-10-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.1999.5.2.107
更新日期:1999-04-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章,评审
doi:10.1179/oeh.1999.5.3.203
更新日期:1999-07-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2006.12.3.234
更新日期:2006-07-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2006.12.4.329
更新日期:2006-10-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.1999.5.1.1
更新日期:1999-01-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2009.15.4.392
更新日期:2009-10-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.1996.2.3.165
更新日期:1996-07-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2005.11.1.45
更新日期:2005-01-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/107735202800338696
更新日期:2002-10-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.1996.2.4.264
更新日期:1996-10-01 00:00:00
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journal_title:International journal of occupational and environmental health
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doi:10.1179/oeh.1997.3.4.300
更新日期:1997-10-01 00:00:00
abstract::Prevalence of hand dermatitis was investigated in 60 U.K. hairdressing salons. Exposure variables and individual characteristics were examined for associations with prevalence. 38.6% of respondents reported prevalent hand dermatitis and 72.7% of prevalent cases reported interdigital symptoms. Trainee hairdressers repo...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
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更新日期:2005-07-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章,评审
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更新日期:2002-01-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/107735201800339614
更新日期:2001-01-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
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更新日期:2007-04-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2006.12.2.111
更新日期:2006-04-01 00:00:00
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journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2004.10.1.1
更新日期:2004-01-01 00:00:00
abstract::A survey of children from a community adjacent to an auto-battery-recycling smelter in Haina, the Dominican Republic, revealed alarming elevations of blood lead (B-Pb) and erythrocyte protoporphyrin (EP-ZnPP) compared with controls. The authors recommend follow-up confirmation and treatment of severely lead-poisoned c...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.1999.5.4.307
更新日期:1999-10-01 00:00:00
abstract::During the 1991 Gulf War, some Allied troops were potentially exposed to sarin/cyclosarin as the result of the destruction of Iraqi munitions at Khamisiyah. To evaluate the prevalence of past and current symptoms known to be associated with exposure to these chemical warfare agents, the authors conducted a computer-as...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/107735201800339515
更新日期:2001-04-01 00:00:00
abstract::In 1983, in the face of mounting evidence of excess leukemia among workers at Shell Oil's Wood River (IL) and Deer Park (TX) petroleum refineries, Shell initiated the Benzene Historical Exposure Study (BHES). Shell's prior research had implicated occupational exposure to benzene as the source of the excess leukemia. T...
journal_title:International journal of occupational and environmental health
pub_type: 历史文章,杂志文章
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更新日期:2007-04-01 00:00:00
abstract::Sixty-five farmers reported on pesticide use and the signs and symptoms of acute pesticide poisoning when using two different plant protection strategies: in 2003 using chemical controls and in 2004 using an approach to Integrated Pest Management (IPM) based on an ecological analysis of the field conditions. Exposure ...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.2009.15.2.143
更新日期:2009-04-01 00:00:00
abstract::From the 1990 National Health Interview Survey Health Promotion and Disease Prevention supplement, the authors estimated the 1990 baseline prevalence of breast cancer screening among employed U.S. women aged 50-70 years. Proportions of women screened for breast cancer were calculated by occupational category and demog...
journal_title:International journal of occupational and environmental health
pub_type: 杂志文章
doi:10.1179/oeh.1995.1.3.225
更新日期:1995-07-01 00:00:00