Amyotrophic lateral sclerosis in a battery-factory worker exposed to cadmium.

Abstract:

:A 44-year-old patient died from amyotrophic lateral sclerosis (ALS) after nine years of heavy exposure to cadmium (Cd) in a nickel cadmium (Ni-Cd) battery factory. Two years after starting work he and co-workers had experienced pruritus, loss of smell, nasal congestion, nosebleeds, cough, shortness of breath, severe headaches, bone pain, and proteinuria. Upper back pain and muscle weakness progressed to flaccid paralysis. EMG findings were consistent with motor neuron disease. Cd impairs the blood-brain barrier, reduces levels of brain copper-zinc (Cu-Zn) superoxide dismutase (SOD), and enhances excitoxicity of glutamate via up-regulation of glutamate dehydrogenase and down-regulation of glutamate uptake in glial cells. High levels of methallothionein, a sign of exposure to heavy metals, have been found in brain tissue of deceased ALS patients. The effects of Cd on enzyme systems that mediate neurotoxicity and motor neuron disease suggest a cause effect relationship between Cd and ALS in this worker.

authors

Bar-Sela S,Reingold S,Richter ED

doi

10.1179/107735201800339470

keywords:

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

109-12

issue

2

eissn

1077-3525

issn

2049-3967

journal_volume

7

pub_type

杂志文章
  • Determinants of health in seasonal migrants: coffee harvesters in Los Santos, Costa Rica.

    abstract::In the agroexport zone of Los Santos Zone in Costa Rica, coffee is harvested by migrant labor. Most migrants are from Panama and Nicaragua. We describe migrants' housing- and service-related health determinants, with analyses of ethnicity, nationality and geography. We used interviews, observation-based assessments, a...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2008.14.2.129

    authors: Loría Bolaños R,Partanen T,Berrocal M,Alvárez B,Córdoba L

    更新日期:2008-04-01 00:00:00

  • Workplace injuries and risk reduction practices in Malaysia.

    abstract:INTRODUCTION:This study on workplace injuries and risk reduction practices was part of the Malaysia National Health Morbidity Survey III (NHMS III) conducted in 2006. METHODS:This cross-sectional population-based survey was conducted to determine the incidence of workplaces injuries and assess the magnitude of some i...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/1077352512Z.00000000035

    authors: Ali R,Shaharudin R,Omar A,Yusoff F

    更新日期:2012-10-01 00:00:00

  • Collaborative field research and training in occupational health and ergonomics.

    abstract::Networking collaborative research and training in Asian developing countries includes three types of joint activities: field studies of workplace potentials for better safety and health, intensive action training for improvement of working conditions in small enterprises, and action-oriented workshops on low-cost impr...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章,评审

    doi:10.1179/oeh.1998.4.3.189

    authors: Kogi K

    更新日期:1998-07-01 00:00:00

  • Assessing occupational exposure to sea lamprey pesticides.

    abstract:BACKGROUND:Sea lampreys are parasitic fish found in lakes of the United States and Canada. Sea lamprey is controlled through manual application of the pesticides 3-trifluoromethyl-4-nitrophenol (TFM) and Bayluscide(TM) into streams and tributaries. 3-Trifluoromethyl-4-nitrophenol may cause irritation and central nervou...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/2049396715Y.0000000002

    authors: Ceballos DM,Beaucham CC,Kurtz K,Musolin K

    更新日期:2015-01-01 00:00:00

  • Current Perspectives on Occupational Cancer Risks.

    abstract::On the basis of the International Agency for Research on Cancer's evaluations of occupational exposures, 22 occupational agents are classified as human carcinogens and an additional 22 agents as probable human carcinogens. In addition, evidence of increased risk of cancer was associated with particular industries and ...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1995.1.4.315

    authors: Boffetta P,Kogevinas M,Simonato L,Wilbourn J,Saracci R

    更新日期:1995-10-01 00:00:00

  • Respiratory symptoms and pulmonary function changes among carpet weavers in Iran.

    abstract::Respiratory and allergic symptoms were evaluated in 66 Iranian carpet weavers and 66 controls with similar age and gender characteristics using a questionnaire including questions on work-related respiratory symptoms in the past year, allergies, smoking habits, and work exposure duration. A total of 28 carpet weavers ...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2007.13.4.369

    authors: Boskabady MH,Karimiani EG,Vostacolaei HA

    更新日期:2007-10-01 00:00:00

  • Exposure to polychlorinated biphenyls (PCBs) among welders in Sri Lanka.

    abstract::Polychlorinated biphenyls (PCBs) are a group of persistent organic pollutants with the ability to cause adverse impacts on human health and the environment. This study describes the indiscriminate use of PCB-contaminated transformer oil as a coolant in informal welding shops in Kalutara, Sri Lanka. Sixty-three welder...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/1077352512Z.00000000012

    authors: Lankatilake K,Samaranayake D,Piyathunga K

    更新日期:2012-04-01 00:00:00

  • Human exposures to arsenic from consumption of well water in West Bengal, India.

    abstract::The authors visited the State of West Bengal, India, in August 1996, as consultants to the World Health Organization (WHO). The general mandate of the mission was to formulate recommendations to the Government of India regarding its efforts to assist the Government of West Bengal in remedying health problems arising f...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章,评审

    doi:10.1179/oeh.1998.4.4.217

    authors: Subramanian KS,Kosnett MJ

    更新日期:1998-10-01 00:00:00

  • Determinants of blood lead levels in Saudi Arabian schoolgirls.

    abstract::Blood lead levels were measured in 538 girls aged 6 to 12 years who attended primary public schools in Riyadh, Saudi Arabia. Of the 538 screened children, 24.4% had blood lead levels > or =10 microg/dL, the Centers for Disease Control's level of concern. Variation in the blood lead levels was investigated with respect...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1999.5.2.107

    authors: Al-Saleh I,Nester M,DeVol E,Shinwari N,Al-Shahria S

    更新日期:1999-04-01 00:00:00

  • The role of information dissemination in sustainability of international partnerships.

    abstract::The Fogarty-supported International Training Program of the Southwest Center for Occupational and Environmental Health (SWCOEH) at the University of Texas School of Public Health was initiated in 1995, with its activities focused primarily on Latin America. As this program has matured, its participants have been conce...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章,评审

    doi:10.1179/oeh.1999.5.3.203

    authors: Delclos GL,Felknor SA,Morandi MT,Schulze LJ,Tovar LS,Yanes L

    更新日期:1999-07-01 00:00:00

  • Cancer incidence and mortality in the industrial city of Sumgayit, Azerbaijan.

    abstract::This study, the first environmental cancer study in Azerbaijan, addressed concerns that residents of the industrial city of Sumgayit have an increased cancer burden as a consequence of intense occupational and environmental pollution from industry. Vital statistics data were used to calculate annual crude cancer incid...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2006.12.3.234

    authors: Andruchow JE,Soskolne CL,Racioppi F,Senthilselvan A,Makhmudov E,Asadov A

    更新日期:2006-07-01 00:00:00

  • Identifying antecedent conditions responsible for the high rate of mining injuries in Zambia.

    abstract::The incident rates of mining-related accidents and injuries in developing countries exceed those of developed nations. Interventions by international organizations routinely fail to produce appreciable long-term improvement. One major reason is the inability to identify and analyze the underlying factors responsible f...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2006.12.4.329

    authors: Miller HB,Sinkala T,Renger RF,Peacock EM,Tabor JA,Burgess JL

    更新日期:2006-10-01 00:00:00

  • An evaluation of the incidence of work-related asthma in the United States.

    abstract::The objective of the study was to estimate the incidences of physician-diagnosed cases of work-related asthma (WRA) in Michigan and the entire United States. The statewide surveillance system for WRA in Michigan receives reports primarily from three sources: physicians, hospital discharge data, and worker's compensati...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1999.5.1.1

    authors: Henneberger PK,Kreiss K,Rosenman KD,Reilly MJ,Chang YF,Geidenberger CA

    更新日期:1999-01-01 00:00:00

  • Factors associated with total restrictions on smoking at work and at home: a study among populations in multiple US states and the US Virgin Islands.

    abstract::This study investigated factors associated with smoking restrictions in the workplace and at home in order to better understand the effects of workplace smoking restrictions. Data from the 2006 Behavior Risk Factor Surveillance System were analyzed. Multiple logistic regression was used to determine independent risk f...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2009.15.4.392

    authors: Cook DM,Lee WL,Yang W

    更新日期:2009-10-01 00:00:00

  • Environmental Exposure to Organic Mercury among the Makuxi in the Amazon Basin.

    abstract::Gold mining in the savannah region of northern Brazil (Roraima) has increased dramatically since 1989. Elemental mercury is used to extract gold from sediment. Mercury released into the Amazon aquatic ecosystem may convert into the organic form and bioconcentrate in the food chain, posing a hazard for fish-eating peop...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1996.2.3.165

    authors: Sing KA,Hryhorczuk DO,Saffirio G,Sinks T,Paschal DC,Chen EH

    更新日期:1996-07-01 00:00:00

  • Evaluation of work-related diseases by the Italian Institute of Insurance for Professional Illness and Injuries (INAIL).

    abstract::Based on a predetermined list of job-related diseases, INAIL makes compensation decisions in cases of work-related diseases in Italy. Its functioning is somewhat hampered by imprecision in the disease classification and infrequency of updating the list, as well as rapid turnover of workers in some categories of jobs. ...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2005.11.1.45

    authors: Bracci C,Norcia G

    更新日期:2005-01-01 00:00:00

  • Feasibility of maternity protection in early pregnancy.

    abstract::Many countries have maternity protection laws for women who need job modification or medical leave during pregnancy. This approach will prevent birth defects only if maternal job changes can be made before the critical period of organogenesis, which begins at three weeks' gestation. The authors studied the gestational...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/107735202800338696

    authors: Von Busch TA,Frazier LM,Sigler SJ,Molgaard CA

    更新日期:2002-10-01 00:00:00

  • Reduction of Acute Low Back Injuries by Use of Back Supports.

    abstract::The objective of this study was to determine the effect of a change in back-support-use policy on the occurrence of work-related low back injuries among a large cohort of employees in the retail-trade home improvement industry. Working hours of exposure, back support use, and intensity of materials-lifting requirement...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1996.2.4.264

    authors: Kraus JF,Brown KA,McArthur DL,Peek-Asa C,Samaniego L,Kraus C

    更新日期:1996-10-01 00:00:00

  • Allergic and Irritant Glove-related Diseases in Health Care Workers and Their Prevention.

    abstract::Because the widespread use of gloves by health care workers has induced an increase of both irritant and type I or type IV allergic glove-related diseases, the Italian Society of Preventive Medicine for Health Care Workers set up a working group to collect information about glove composition and to standardize procedu...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1997.3.4.300

    authors: Alessio L,Baruffini A,Biscaldi G,Cirla AM,Cortona G,Crippa M,Franco G,Marcer G,Moscato G,Toffoletto F

    更新日期:1997-10-01 00:00:00

  • Prevalence of occupational hand dermatitis in U.K. hairdressers.

    abstract::Prevalence of hand dermatitis was investigated in 60 U.K. hairdressing salons. Exposure variables and individual characteristics were examined for associations with prevalence. 38.6% of respondents reported prevalent hand dermatitis and 72.7% of prevalent cases reported interdigital symptoms. Trainee hairdressers repo...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/107735205800245920

    authors: Perkins JB,Farrow A

    更新日期:2005-07-01 00:00:00

  • Pesticide usage and health consequences for women in developing countries: out of sight, out of mind?

    abstract::Pesticide exposures of women in developing countries are aggravated by economic policy changes associated with structural adjustment programs and globalization. Women in these countries, particularly in the agricultural sector, are increasingly exposed. Since they are concentrated in the most marginal positions in the...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章,评审

    doi:10.1179/oeh.2002.8.1.46

    authors: London L,de GS,Wesseling C,Kisting S,Rother HA,Mergler D

    更新日期:2002-01-01 00:00:00

  • Worksite and personal factors associated with carpal tunnel syndrome in an Egyptian electronics assembly factory.

    abstract::The study objective was to identify personal and work-related risk factors associated with carpal tunnel syndrome (CTS) in electronics assembly, operators relative to clerical workers in the same factory. Of 422 workers in a television assembly factory located in Ismailia, Suez Canal Area, Egypt, 198 (46.9%) participa...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/107735201800339614

    authors: Abbas MF,Faris RH,Harber PI,Mishriky AM,El-Shahaly HA,Waheeb YH,Kraus JF

    更新日期:2001-01-01 00:00:00

  • Comparison bias and dilution effect in occupational cohort studies.

    abstract::Health effects of occupational exposures are frequently evaluated by comparing the mortality of a whole cohort of workers with that of the general population. This study design may be affected by two major biases: a dilution effect (DE), due to the inclusion of unexposed subjects in the study cohort, and a comparison ...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2007.13.2.143

    authors: Parodi S,Gennaro V,Ceppi M,Cocco P

    更新日期:2007-04-01 00:00:00

  • Psychosocial work environment and mental health: Job-strain and effort-reward imbalance models in a context of major organizational changes.

    abstract::This study explored the association between the two job-stress models, job-strain and effort-reward imbalance, and mental health outcomes in a working population exposed to major organizational changes. The cross-sectional study was based on 680 subjects, 504 men and 176 women. Psychosocial factors at work included: p...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2006.12.2.111

    authors: Niedhammer I,Chastang JF,David S,Barouhiel L,Barrandon G

    更新日期:2006-04-01 00:00:00

  • Medical evaluation of work-related illness: evaluations by a treating occupational medicine specialist and by independent medical examiners compared.

    abstract::Treating physicians' and independent medical examiners' (IMEs') opinions were compared to identify differences of opinion and to develop a basis for understanding the differences. Twenty-three patients of an occupational health center (OHC) who had been examined by an IME were studied. OHC and IME opinions regarding d...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2004.10.1.1

    authors: Lax MB,Manetti FA,Klein RA

    更新日期:2004-01-01 00:00:00

  • Elevated blood lead and erythrocyte protoporphyrin levels of children near a battery-recycling plant in Haina, Dominican Republic.

    abstract::A survey of children from a community adjacent to an auto-battery-recycling smelter in Haina, the Dominican Republic, revealed alarming elevations of blood lead (B-Pb) and erythrocyte protoporphyrin (EP-ZnPP) compared with controls. The authors recommend follow-up confirmation and treatment of severely lead-poisoned c...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1999.5.4.307

    authors: Kaul B,Mukerjee H

    更新日期:1999-10-01 00:00:00

  • Symptoms of Gulf War veterans possibly exposed to organophosphate chemical warfare agents at Khamisiyah, Iraq.

    abstract::During the 1991 Gulf War, some Allied troops were potentially exposed to sarin/cyclosarin as the result of the destruction of Iraqi munitions at Khamisiyah. To evaluate the prevalence of past and current symptoms known to be associated with exposure to these chemical warfare agents, the authors conducted a computer-as...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/107735201800339515

    authors: McCauley LA,Rischitelli G,Lambert WE,Lasarev M,Sticker DL,Spencer PS

    更新日期:2001-04-01 00:00:00

  • Manipulated data in Shell's Benzene Historical Exposure Study.

    abstract::In 1983, in the face of mounting evidence of excess leukemia among workers at Shell Oil's Wood River (IL) and Deer Park (TX) petroleum refineries, Shell initiated the Benzene Historical Exposure Study (BHES). Shell's prior research had implicated occupational exposure to benzene as the source of the excess leukemia. T...

    journal_title:International journal of occupational and environmental health

    pub_type: 历史文章,杂志文章

    doi:10.1179/oeh.2007.13.2.222

    authors: Egilman D,Scout,Kol L,Hegg LA,Bohme SR

    更新日期:2007-04-01 00:00:00

  • Reducing the incidence of acute pesticide poisoning by educating farmers on integrated pest management in South India.

    abstract::Sixty-five farmers reported on pesticide use and the signs and symptoms of acute pesticide poisoning when using two different plant protection strategies: in 2003 using chemical controls and in 2004 using an approach to Integrated Pest Management (IPM) based on an ecological analysis of the field conditions. Exposure ...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.2009.15.2.143

    authors: Mancini F,Jiggins JL,O'Malley M

    更新日期:2009-04-01 00:00:00

  • Breast Cancer Screening among Employed American Women.

    abstract::From the 1990 National Health Interview Survey Health Promotion and Disease Prevention supplement, the authors estimated the 1990 baseline prevalence of breast cancer screening among employed U.S. women aged 50-70 years. Proportions of women screened for breast cancer were calculated by occupational category and demog...

    journal_title:International journal of occupational and environmental health

    pub_type: 杂志文章

    doi:10.1179/oeh.1995.1.3.225

    authors: Ballard TJ,Burnett CA,Sieber WK,Halperin WE

    更新日期:1995-07-01 00:00:00