Positron emission tomography in the detection and management of sarcomatous transformation in neurofibromatosis.

Abstract:

:Benign neurofibromas undergo sarcomatous transformation in approximately 5% of patients with neurofibromatosis type I. The clinical and radiologic diagnosis of sarcomatous change remains difficult. Positron emission tomography with F-18 fluorodeoxyglucose is a method to assess increased glucose metabolism in malignant tissue such as sarcomas. In this case report, positron emission tomography accurately distinguished malignant from benign neurofibromas. The technique may be useful as a noninvasive screening tool for malignant transformation of neurofibromas.

journal_name

Clin Nucl Med

authors

Solomon SB,Semih Dogan A,Nicol TL,Campbell JN,Pomper MG

doi

10.1097/00003072-200106000-00009

keywords:

subject

Has Abstract

pub_date

2001-06-01 00:00:00

pages

525-8

issue

6

eissn

0363-9762

issn

1536-0229

journal_volume

26

pub_type

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