Expression of cytokine and chemokine genes by human middle ear epithelial cells induced by formalin-killed Haemophilus influenzae or its lipooligosaccharide htrB and rfaD mutants.

abstract：:Helicobacter mustelae, like Helicobacter pylori, possesses two flagellin proteins, FlaA and FlaB. Isogenic mutant strains of H. mustelae have been constructed by disruption of the flaA or flaB gene with a kanamycin resistance cassette or by introduction of both a kanamycin and a chloramphenicol resistance gene to prod...

journal_title：Infection and immunity

authors： Andrutis KA,Fox JG,Schauer DB,Marini RP,Li X,Yan L,Josenhans C,Suerbaum S

更新日期：1997-05-01 00:00:00

abstract：:Cytokine gene expression in cells migrating in afferent and efferent intestinal lymph was monitored for extended time periods in individual sheep experimentally infected with the nematode Trichostrongylus colubriformis. Animals from stable selection lines with increased levels of either genetic resistance (R) or susce...

journal_title：Infection and immunity

authors： Pernthaner A,Cole SA,Morrison L,Hein WR

更新日期：2005-04-01 00:00:00

abstract：:Infection of human monocyte-derived macrophages (HMDM) and J774 cells (murine macrophage cell line) with several enteroaggregative and cytodetaching Escherichia coli (EAggEC and CDEC, respectively) strains demonstrated that some strains could induce macrophage cell death accompanied by release of lactate dehydrogenase...

journal_title：Infection and immunity

authors： Fernandez-Prada C,Tall BD,Elliott SE,Hoover DL,Nataro JP,Venkatesan MM

更新日期：1998-08-01 00:00:00

abstract：:Mycobacterium marinum grows at an optimal temperature of 33 degrees C, far lower than that for M. tuberculosis. Consequently, M. marinum infection of mammals is restricted largely to the cooler surfaces of the body, such as the extremities, but it causes a systemic infection in a large number of poikilothermic animals...

journal_title：Infection and immunity

authors： Ramakrishnan L,Valdivia RH,McKerrow JH,Falkow S

更新日期：1997-02-01 00:00:00

abstract：:Neutrophil serine proteases cathepsin G (CG), neutrophil elastase (NE), and proteinase 3 (PR3) have recently been shown to contribute to killing of Streptococcus pneumoniae in vitro. However, their relevance in lung-protective immunity against different serotypes of S. pneumoniae in vivo has not been determined so far...

journal_title：Infection and immunity

authors： Hahn I,Klaus A,Janze AK,Steinwede K,Ding N,Bohling J,Brumshagen C,Serrano H,Gauthier F,Paton JC,Welte T,Maus UA

更新日期：2011-12-01 00:00:00

abstract：:The microbicidal myeloperoxidase (MPO)-H2O2-chloride system strongly inhibits Escherichia coli DNA synthesis. Also, cell envelopes from MPO-treated E. coli cells lose their ability to interact with hemimethylated DNA sequences of oriC, the chromosomal origin of replication, raising the prospect that suppression of DNA...

journal_title：Infection and immunity

authors： Rosen H,Michel BR,vanDevanter DR,Hughes JP

更新日期：1998-06-01 00:00:00

abstract：:Pyolysin (PLO), a cholesterol-dependent cytolysin expressed by Arcanobacterium pyogenes, is an important host-protective antigen. However, this molecule is toxic and requires inactivation prior to its use as a vaccine. Three genetically toxoided, nonhemolytic PLO molecules, HIS-PLO.F(497), HIS-PLO.Delta P(499), and HI...

journal_title：Infection and immunity

authors： Jost BH,Trinh HT,Songer JG,Billington SJ

更新日期：2003-05-01 00:00:00

abstract：:Mice were infected with 170 Trichinella spiralis larvae, and their blood clearance of carbon particles was studied 4, 7, 13, 32, and 135 days later and compared with that of noninfected control mice. Clearance in mice with a 4-day-old infection was comparable to that in the controls; clearances in mice with 7- and 13-...

journal_title：Infection and immunity

authors： Barriga OO

更新日期：1980-12-01 00:00:00

abstract：:The epitope specificities of 13 hybridomas secreting monoclonal antibodies (MAbs) specific for pertussis toxin (PT) is described. Hybridoma lines were derived by the fusion of spleen cells from mice immunized with native PT, Formalin-detoxified PT, or isolated PT subunits (S1 to S5) with the myeloma line X63-Ag8.653. ...

journal_title：Infection and immunity

authors： Lang AB,Ganss MT,Cryz SJ Jr

更新日期：1989-09-01 00:00:00

abstract：:Extracytoplasmic proteins were released from Serpulina (Treponema) hyodysenteriae (strain B204) by treatment of whole cells with a nonionic detergent (Tween 20). Centrifugation of the Tween 20-released proteins at 100,000 x g sedimented 10 major extracytoplasmic proteins with approximate molecular masses of 44, 43.5, ...

journal_title：Infection and immunity

authors： Gabe JD,Chang RJ,Slomiany R,Andrews WH,McCaman MT

更新日期：1995-01-01 00:00:00

abstract：:Two weeks after mice had been infected in the footpad with cells of Nocardia brasiliensis, immunoglobulin and C3 deposits were observed in tissue from the inoculation site. Both immunoglobulin and C3 were found in the actinomycotic granules that characterize the mycetoma and in the surrounding inflammatory zones, in w...

journal_title：Infection and immunity

authors： Conde C,Mancilla R,Fresan M,Ortiz-Ortiz L

更新日期：1983-06-01 00:00:00

abstract：:Both dextransucrase and mutansynthetase activities have been purified from the culture fluids of Streptococcus mutans GS-5 (serotype c). Although homogeneous dextransucrase preparations normally synthesize little insoluble glucan, essentially all of the glucan synthesized by this enzyme in the presence of 1.5 M (NH4)2...

journal_title：Infection and immunity

authors： Kuramitsu HK,Wondrack L

更新日期：1983-11-01 00:00:00

abstract：:Previous studies have indicated that the ability to bind to fibronectin is a key feature in successful cell invasion by Campylobacter jejuni. Given the spatial distribution of fibronectin and the architecture of the epithelium, this suggests the possibility that C. jejuni cell invasion might preferentially occur at th...

journal_title：Infection and immunity

authors： Monteville MR,Konkel ME

更新日期：2002-12-01 00:00:00

abstract：:Neutrophils play a major role in defending the periodontium against infection by oral, gram-negative, facultative bacteria, such as Actinobacillus actinomycetemcomitans, Eikenella corrodens, and Capnocytophaga spp. We examined the sensitivity of these bacteria to a mixture of low-molecular-weight peptides and highly p...

journal_title：Infection and immunity

authors： Miyasaki KT,Bodeau AL,Ganz T,Selsted ME,Lehrer RI

更新日期：1990-12-01 00:00:00

abstract：:Staphylococcus aureus Newman with an insertion mutation in clfB, the gene encoding clumping factor B, only marginally decreased infection rate (P>0.05) in rats with experimental endocarditis. In contrast, clfB complementation on a multicopy plasmid significantly increased infectivity (P<0.05) over the deleted mutants....

journal_title：Infection and immunity

authors： Entenza JM,Foster TJ,Ni Eidhin D,Vaudaux P,Francioli P,Moreillon P

更新日期：2000-09-01 00:00:00

abstract：:Mice infected with various strains of Salmonella enteritidis and S. typhimurium were found to be more sensitive to the cell wall lipopolysaccharide (LPS) extracted from certain strains of Salmonella than noninfected mice. This hypersensitivity was induced by those smooth or rough strains which possessed a polysacchari...

journal_title：Infection and immunity

authors： Kawakami M,Hara Y,Osawa N

更新日期：1971-11-01 00:00:00

abstract：:We investigated the ability of two overlapping fragments of staphylococcal enterotoxin B (SEB), which encompass the whole toxin, to induce protection and also examined if passive transfer of chicken anti-SEB antibodies raised against the holotoxin could protect rhesus monkeys against aerosolized SEB. Although both fra...

journal_title：Infection and immunity

authors： LeClaire RD,Hunt RE,Bavari S

更新日期：2002-05-01 00:00:00

abstract：:The purpose of the present study was to analyze Chlamydia pneumoniae-induced, antigen-specific, cell-mediated immunity. Peripheral blood mononuclear cells of four persons infected with C. pneumoniae Kajaani 6 and 17 healthy volunteers were stimulated with antigen composed of whole elementary bodies of C. pneumoniae Ka...

journal_title：Infection and immunity

authors： Surcel HM,Syrjälä H,Leinonen M,Saikku P,Herva E

更新日期：1993-05-01 00:00:00

abstract：:Inactivated Marek's disease virus-infected chicken kidney cells and inactivated MSB-1 lymphoblastoid Marek's disease tumor cells were used to immunize chickens as virus- and tumor-associated antigens, respectively. Immune and nonimmune birds were then challenged by exposure to live virulent Marek's disease virus. Both...

journal_title：Infection and immunity

authors： Murthy KK,Calnek BW

更新日期：1979-11-01 00:00:00

abstract：:A 95-kDa protein was isolated from Staphylococcus saprophyticus 7108 grown on dialysis membranes placed on the surface of brain heart infusion agar. Strain CCM883 did not produce this protein. Ultrathin sections revealed the presence of very thin, tuftlike, 50- to 75-nm-long structures on the surface of strain 7108, w...

journal_title：Infection and immunity

authors： Gatermann S,Kreft B,Marre R,Wanner G

更新日期：1992-03-01 00:00:00

abstract：:We investigated the role of bacterial mannose-resistant fimbriation of S fimbriae (Fim), mannose-resistant hemagglutination (S-Mrh), and hemolysin (Hly) production by an Escherichia coli parent and genetically cloned strains as regards their effect on histamine release from rat mast cells and generation of the chemilu...

journal_title：Infection and immunity

authors： König B,König W,Scheffer J,Hacker J,Goebel W

更新日期：1986-12-01 00:00:00

abstract：:Salmonella is a widespread zoonotic enteropathogen that causes gastroenteritis and fatal typhoidal disease in mammals. During systemic infection of mice, Salmonella enterica serovar Typhimurium resides and replicates in macrophages within the "Salmonella-containing vacuole" (SCV). It is surprising that the substrates ...

journal_title：Infection and immunity

authors： Bowden SD,Rowley G,Hinton JC,Thompson A

更新日期：2009-07-01 00:00:00

abstract：:Borrelia burgdorferi elicits a potent cytokine response through activation of multiple signaling receptors on innate immune cells. Spirochetal lipoproteins initiate expression of NF-κB-dependent cytokines primarily via TLR2, whereas type I interferon (IFN) production is induced through the endosomal receptors TLR7 and...

journal_title：Infection and immunity

authors： Love AC,Schwartz I,Petzke MM

更新日期：2014-06-01 00:00:00

abstract：:Polymorphonuclear leukocytes (PMN) isolated from human blood were exposed to various levels of hydrogen sulfide. The effect on respiratory burst, myeloperoxidase activity, and capacity to phagocytose and kill bacteria were studied. A 1-h exposure of the PMN to 1 mM sulfide did not decrease their myeloperoxidase activi...

journal_title：Infection and immunity

authors： Claesson R,Granlund-Edstedt M,Persson S,Carlsson J

更新日期：1989-09-01 00:00:00

abstract：:The pattern of meningococcal surface structure expression in different microenvironments following bloodstream invasion in vivo is not known. We used immunohistochemistry to determine the expression of capsule, type IV pili, and PorA by meningococci residing in the skin lesions of children with purpura fulminans. All ...

journal_title：Infection and immunity

authors： Harrison OB,Robertson BD,Faust SN,Jepson MA,Goldin RD,Levin M,Heyderman RS

更新日期：2002-09-01 00:00:00

abstract：:Attachment of Fusobacterium nucleatum to various oral surfaces is mediated by several adhesins anchored on its outer surface. Monoclonal antibodies (MAbs) were prepared and used to identify the putative galactose-binding adhesin of F. nucleatum PK1594. Four unique MAbs, 8G7, 26B9, 28G11, and 29D4, were isolated on the...

journal_title：Infection and immunity

authors： Shaniztki B,Hurwitz D,Smorodinsky N,Ganeshkumar N,Weiss EI

更新日期：1997-12-01 00:00:00

abstract：:The expression of the Shigella flexneri chromosomal aerobactin genes during growth of the bacterium within tissue culture cells was assayed. During intracellular growth, aerobactin promoter activity was repressed relative to the level observed in bacteria grown extracellularly, even when the bacteria had been starved ...

journal_title：Infection and immunity

authors： Headley V,Hong M,Galko M,Payne SM

更新日期：1997-02-01 00:00:00

abstract：:Antibiotics suppressed development of aster yellows (AY) disease symptoms in plants of china aster [Callistephus chinensis (L.) Nees.] and annual chrysanthemum (Chrysanthemum carinatum, Schousb.). When inoculated chrysanthemum plants were treated by any of several techniques with tetracycline antibiotics or chloramphe...

journal_title：Infection and immunity

authors： Davis RE,Whitcomb RF

更新日期：1970-08-01 00:00:00

abstract：:In mammalian hosts, Leishmania sp. parasites are obligatory intracellular organisms that invade macrophages and dendritic cells (DC), where they reside in endocytic organelles termed parasitophorous vacuoles (PV). Most of the present knowledge of the characteristics of PV harboring Leishmania sp. is derived from studi...

journal_title：Infection and immunity

authors： Körner U,Fuss V,Steigerwald J,Moll H

更新日期：2006-02-01 00:00:00

abstract：:A heterogeneous subset of extraintestinal pathogenic Escherichia coli (ExPEC) strains, referred to as uropathogenic E. coli (UPEC), causes most uncomplicated urinary tract infections. However, no core set of virulence factors exists among UPEC strains. Instead, the focus of the analysis of urovirulence has shifted to ...

journal_title：Infection and immunity

authors： Engstrom MD,Alteri CJ,Mobley HL

更新日期：2014-09-01 00:00:00