Optimization of differential photodynamic effectiveness between normal and tumor urothelial cells using 5-aminolevulinic acid-induced protoporphyrin IX as sensitizer.

abstract：:Adenovirus early region 4 open reading frame 4 (E4orf4) protein is a novel cell death factor that selectively induces apoptosis in cancer cells. This study evaluated tumor inhibitory effects of a protein made by fusion E4orf4 and human epidermal growth factor (EGF). EGF was used to ensure the selective targeting of EG...

journal_title：International journal of cancer

authors： Zhou Y,Chen H,Ma XL,Xie HJ,Wang CL,Zhang SH,Wang X,Huang BR

更新日期：2009-09-01 00:00:00

abstract：:We have studied the occurrence and association of 11q deletions with other chromosomal imbalances in Stage 4 neuroblastomas. To this purpose we have performed comparative genomic hybridization (CGH) analysis on 50 Stage 4 neuroblastomas and these data were analyzed together with those from 33 previously published case...

journal_title：International journal of cancer

authors： Plantaz D,Vandesompele J,Van Roy N,Lastowska M,Bown N,Combaret V,Favrot MC,Delattre O,Michon J,Bénard J,Hartmann O,Nicholson JC,Ross FM,Brinkschmidt C,Laureys G,Caron H,Matthay KK,Feuerstein BG,Speleman F

更新日期：2001-03-01 00:00:00

abstract：:Inhibition of programmed cell death (apoptosis) is associated with increased tumor aggressiveness. We hypothesized that a novel sensitive to apoptosis gene, SAG, may be expressed in tumors of patients with nonsmall cell lung cancer (NSCLC) and may affect their clinical outcome. Expression of SAG messenger RNA was eval...

journal_title：International journal of cancer

authors： Sasaki H,Yukiue H,Kobayashi Y,Moriyama S,Nakashima Y,Kaji M,Fukai I,Kiriyama M,Yamakawa Y,Fujii Y

更新日期：2001-11-20 00:00:00

abstract：:Somatic mutations in the TP53 gene are the most frequently observed genetic alterations in human malignancies, including breast cancer, which is one of the leading causes of death among women in Brazil. In our study, we determined the frequency and the pattern of TP53 mutations in malignant breast tumors from 120 pati...

journal_title：International journal of cancer

authors： Simão TA,Ribeiro FS,Amorim LM,Albano RM,Andrada-Serpa MJ,Cardoso LE,Mendonça GA,de Moura-Gallo CV

更新日期：2002-09-01 00:00:00

abstract：:Pancreatic cancer is almost always fatal, in part because of its delayed diagnosis, poor prognosis, rapid progression and chemoresistance. Oncogenic proteins are stabilized by the Hsp90, making it a potential therapeutic target. We investigated the oxidative stress-mediated dysfunction of Hsp90 and the hindrance of it...

journal_title：International journal of cancer

authors： Sarkar S,Dutta D,Samanta SK,Bhattacharya K,Pal BC,Li J,Datta K,Mandal C,Mandal C

更新日期：2013-02-01 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta1) is a potent negative regulator of cell growth that transduces signals through interactions with type I and II receptors. Abnormal expression and mutational alterations of these receptors have been observed in several human malignancies. In this study, we investigated the exp...

journal_title：International journal of cancer

authors： Guo Y,Jacobs SC,Kyprianou N

更新日期：1997-05-16 00:00:00

abstract：:The population of Leningrad suffered from severe starvation, cold and psychological stress during the siege in World War II in 1941-1944. We investigated the long-term effects of the siege on cancer mortality in 3,901 men and 1,429 women, born between 1910 and 1940. All study subjects were residents of St. Petersburg,...

journal_title：International journal of cancer

authors： Koupil I,Plavinskaja S,Parfenova N,Shestov DB,Danziger PD,Vågerö D

更新日期：2009-03-15 00:00:00

abstract：:We evaluated RS5444, a thiazolidinedione high affinity PPARgamma agonist, for the ability to inhibit colon carcinogenesis in azoxymethane (AOM)-treated mice. In our initial experiment, mice were treated with RS5444 during AOM treatment, and the drug was withdrawn 12 weeks after the last injection of AOM. RS5444 signif...

journal_title：International journal of cancer

authors： Su W,Necela BM,Fujiwara K,Kurakata S,Murray NR,Fields AP,Thompson EA

更新日期：2008-09-01 00:00:00

abstract：:Renal-cell carcinomas (RCC) are clinically, histologically and cytogenetically very heterogeneous. The present histological WHO classification shows no clear correlation between histologic subtypes and specific chromosomal abnormalities. In 1986, a new classification was proposed by Thoenes and Störkel based on the ce...

journal_title：International journal of cancer

authors： van den Berg E,van der Hout AH,Oosterhuis JW,Störkel S,Dijkhuizen T,Dam A,Zweers HM,Mensink HJ,Buys CH,de Jong B

更新日期：1993-09-09 00:00:00

abstract：:The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies on the generation of potent DC capable of presenting tumor antigens such as carcinoembryonic antigen (CEA). It is unknown whether the T cells of patients with advanced malignancies can be reliably stimulated against tumor an...

journal_title：International journal of cancer

authors： Nair SK,Hull S,Coleman D,Gilboa E,Lyerly HK,Morse MA

更新日期：1999-07-02 00:00:00

abstract：:It is considered that fruit and vegetable (F&V) protect against oesophagus and gastric cancer (GC). However, 2 recent meta-analyses suggest that the strength of association on GC seems to be weaker for vegetables than for fruit and weaker in cohort than in case-control studies. No evidence exists from cohort studies a...

journal_title：International journal of cancer

authors： González CA,Pera G,Agudo A,Bueno-de-Mesquita HB,Ceroti M,Boeing H,Schulz M,Del Giudice G,Plebani M,Carneiro F,Berrino F,Sacerdote C,Tumino R,Panico S,Berglund G,Simán H,Hallmans G,Stenling R,Martinez C,Dorronsoro M

更新日期：2006-05-15 00:00:00

abstract：:Meningioma, the most frequent tumor in the central nervous system, has few recognized risk factors. We explored the role of allergies in a population-based case-control consortium study of meningioma in five geographic areas. We also studied serum levels of a marker of atopic allergy (IgE) in a subset of study partici...

journal_title：International journal of cancer

authors： Wiemels JL,Wrensch M,Sison JD,Zhou M,Bondy M,Calvocoressi L,Black PM,Yu H,Schildkraut JM,Claus EB

更新日期：2011-10-15 00:00:00

abstract：:Female residents of six counties in Washington and Utah in whom a diagnosis of ovarian cancer was made during 1975-79 were interviewed concerning prior use of oral contraceptives. Interviews with a random sample of women drawn from these same counties were obtained for comparison. A smaller proportion of women with ep...

journal_title：International journal of cancer

authors： Weiss NS,Lyon JL,Liff JM,Vollmer WM,Daling JR

更新日期：1981-12-01 00:00:00

abstract：:The Eph receptor A2 (EphA2) is overexpressed in a range of human epithelial cancers, a phenotype that is associated with cancer cell proliferation, progression and angiogenesis. Mouse models of mammary neoplasia have confirmed the role of EphA2 as mice carrying a knockout allele of EphA2 were resistant to breast cance...

journal_title：International journal of cancer

authors： Bogan C,Chen J,O'Sullivan MG,Cormier RT

更新日期：2009-03-15 00:00:00

abstract：:We examined the geospatial dimension of delays to diagnosis of breast cancer in a prospective study of 1541 women newly diagnosed in the African Breast Cancer - Disparities in Outcomes (ABC-DO) Study. Women were recruited at cancer treatment facilities in Namibia, Nigeria, Uganda, and Zambia. The baseline interview in...

journal_title：International journal of cancer

authors： Togawa K,Anderson BO,Foerster M,Galukande M,Zietsman A,Pontac J,Anele A,Adisa C,Parham G,Pinder LF,McKenzie F,Schüz J,Dos-Santos-Silva I,McCormack V

更新日期：2020-11-16 00:00:00

abstract：:High BCAR1/p130Cas expression in primary breast tumour cytosol predicts a poor chance of response recurrent disease to tamoxifen treatment in patients with oestrogen receptor (ER)-positive breast carcinomas. In this study, we assessed whether BCAR1/p130Cas expression is altered during acquisition of anti-oestrogen res...

journal_title：International journal of cancer

authors： van der Flier S,Chan CM,Brinkman A,Smid M,Johnston SR,Dorssers LC,Dowsett M

更新日期：2000-09-20 00:00:00

abstract：:Our case-control study was conducted to investigate whether residential and occupational exposure to magnetic fields increased the risk for brain tumours in adults. Data from an occupational exposure matrix was also evaluated. The study population in this nested case-control study was made up of subjects aged 16 years...

journal_title：International journal of cancer

authors： Klaeboe L,Blaasaas KG,Haldorsen T,Tynes T

更新日期：2005-05-20 00:00:00

abstract：:Gene therapy and virotherapy are among the approaches currently being used to treat lung cancer. The success of cancer gene therapy depends on treatments where different types of tumors can be selectively targeted and destroyed without affecting normal cells and tissue. Previously, we described a promoter system (TTS)...

journal_title：International journal of cancer

authors： Fukazawa T,Maeda Y,Matsuoka J,Tanaka N,Tanaka H,Durbin ML,Naomoto Y

更新日期：2009-10-15 00:00:00

abstract：:WAVE3, an actin cytoskeleton remodeling protein, is highly expressed in advanced stages of breast cancer and influences tumor cell invasion. Loss of miR-31 has been associated with cancer progression and metastasis. Here, we show that the activity of WAVE3 to promote cancer cell invasion is regulated by miR-31. An inv...

journal_title：International journal of cancer

authors： Sossey-Alaoui K,Downs-Kelly E,Das M,Izem L,Tubbs R,Plow EF

更新日期：2011-09-15 00:00:00

abstract：:Cells of the melanocytic lineage have been shown to be capable of producing laminin and to lose this property during transformation. In the present study, we have evaluated immunohistochemically whether these changes are paralleled by an altered expression of the alpha 6/beta 1 laminin receptor. Results of this analys...

journal_title：International journal of cancer

authors： Natali PG,Nicotra MR,Cavaliere R,Giannarelli D,Bigotti A

更新日期：1991-09-09 00:00:00

abstract：:The activity of systemic and in situ natural killer (NK) cells was measured in 3- to 5-week-old CBA mice with progressively growing murine sarcoma virus (MSV)-induced tumors. Splenic NK activity was depressed in tumor-bearing mice. NK activity was quite low or not detectable in unfractionated cell suspensions from the...

journal_title：International journal of cancer

authors： Gerson J,Varesio L,Herberman RB

更新日期：1981-02-15 00:00:00

abstract：:Mantle cell lymphoma (MCL) is an aggressive and incurable malignant disease. Despite of general chemotherapy, relapse and mortality are common, highlighting the need for the development of novel targeted drugs or combination of therapeutic regimens. Recently, several drugs that target the B-cell receptor (BCR) signali...

journal_title：International journal of cancer

authors： Li J,Wang X,Xie Y,Ying Z,Liu W,Ping L,Zhang C,Pan Z,Ding N,Song Y,Zhu J

更新日期：2018-01-01 00:00:00

abstract：:A case of epidermodysplasia verruciformis in a patient from Upper-Volta is described. Slightly elevated, flat warts were observed on hands, feet, arms and legs, and pityriasis versicolor-like lesions were found mainly on the trunk. The patient showed no malignant tumors. Histological examination revealed hyperkeratosi...

journal_title：International journal of cancer

authors： Pfister H,Nürnberger F,Gissmann L,zur Hausen H

更新日期：1981-05-15 00:00:00

abstract：:There is growing evidence suggesting that cytotoxic activity of cisplatin is closely associated with increased generation of reactive oxygen species (ROS). Therefore, this study was undertaken to examine oxidative DNA damage, which arises as a result of chemotherapy with cisplatin. Using HPLC prepurification/isotope d...

journal_title：International journal of cancer

authors： Siomek A,Tujakowski J,Gackowski D,Rozalski R,Foksinski M,Dziaman T,Roszkowski K,Olinski R

更新日期：2006-11-01 00:00:00

abstract：:Colorectal cancer (CRC) screening rates are currently suboptimal. Blood-based screening could improve rates of earlier detection for CRC and adenomatous colorectal polyps. In this study, we evaluated the feasibility of plasma-based detection of early CRC and adenomatous polyps using array-mediated analysis methylation...

journal_title：International journal of cancer

authors： Cassinotti E,Melson J,Liggett T,Melnikov A,Yi Q,Replogle C,Mobarhan S,Boni L,Segato S,Levenson V

更新日期：2012-09-01 00:00:00

abstract：:Epigenetic alterations play a major role in cancer. Recently we reported that stem cell Polycomb group targets (PcGTs) are up to 12-fold more likely to have cancer-specific promoter DNA hypermethylation than nontargets. To identify potential, prognostic DNA methylation markers in ovarian cancer we analyzed the DNA met...

journal_title：International journal of cancer

authors： Fiegl H,Windbichler G,Mueller-Holzner E,Goebel G,Lechner M,Jacobs IJ,Widschwendter M

更新日期：2008-08-01 00:00:00

abstract：:The characteristics of tumor antigens of the transplantation type, TATA, were studied in a series of methylcholanthrene-induced sarcomas in pedigreed BALB/cAN mice. Each of the six sarcomas exhibited unique TATA when assayed for tumor rejection in syngeneic hosts. In three instances, however, in sarcomas CI-I, CII-5 a...

journal_title：International journal of cancer

authors： Law LW

更新日期：1980-02-15 00:00:00

abstract：:The effect of the glycosylation inhibitor, tunicamycin, on synthesis and secretion of the membrane-associated glycoprotein carcinoembryonic antigen (CEA), was studied in the LS174T human colon cancer cell line. Tunicamycin treatment inhibited total cellular glycoprotein synthesis but did not affect CEA levels of cellu...

journal_title：International journal of cancer

authors： Miura S,Kim YS

更新日期：1986-08-15 00:00:00

abstract：:The subsets of small lymphocytes (surface Igm-positive or B, Thy-I-positive or T and "double-negative" or null) appearing within spontaneous mammary tumors of C3H retired breeder female mice and in various lymphoid organs of the host at different stages of tumor development were characterized directly using a radioaut...

journal_title：International journal of cancer

authors： Santer V,Mastromarino JH,Lala PK

更新日期：1980-01-15 00:00:00

abstract：:A human revertant cell line, derived from non-producer human osteosarcoma cells (NP/KHOS) induced by Kirsten murine sarcoma virus, was treated in vitro with various levels of polycyclic aromatic hydrocarbons (3-methylcholanthrene, 7,12-dimethylbenz(alpha)anthracene, and benzo(alpha)pyrene [BP] or dimethyl sulfoxide (c...

journal_title：International journal of cancer

authors： Cho HY,Arnstein P,Rhim JS

更新日期：1978-01-15 00:00:00