Excision of DNA damage arising from chemicals of different carcinogenic potencies.

Abstract:

:Primary cultures of mouse embryo cells are more efficient in excising DNA-carcinogen adducts resulting from exposure to either 7-bromomethylbenz-[alpha]anthracene or the more carcinogen 7-bromomethyl-12-methylbenz[alpha]anthracene than are mouse L 929 cell suspension cultures. However, within each of these systems, the excisabilities of the adducts formed by either bromo-compound are similar, so differences in carcinogenic potency of the compounds cannot be attributed to differences in the excisability of their DNA-adducts.

journal_name

Cancer Lett

journal_title

Cancer letters

authors

Dipple A,Schultz E

doi

10.1016/s0304-3835(79)80103-2

keywords:

subject

Has Abstract

pub_date

1979-07-01 00:00:00

pages

103-8

issue

2-3

eissn

0304-3835

issn

1872-7980

pii

S0304-3835(79)80103-2

journal_volume

7

pub_type

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