Abstract:
:One of the most remarkable life history traits of many species of eusocial insects is the extraordinary longevity of their queens, with the recorded life span of some individuals exceeding 30 years. Surprisingly, little research has been conducted on either the proximate or ultimate questions concerning what factors favor the evolution of the long life spans in social insects. The broad objective of this paper is to address four sets of questions: (1) What are the similarities and differences in the longevity patterns among species in the four main groups of social insects - bees, wasps, ants and termites? (2) What is the evolutionary association of longevity and sociality in insects? (3) Are there biodemographic principles that can be derived from studies on longevity in social insects? and (4) What are the general implications for longevity in vertebrates, including humans?
journal_name
Exp Gerontoljournal_title
Experimental gerontologyauthors
Carey JRdoi
10.1016/s0531-5565(00)00237-0keywords:
subject
Has Abstractpub_date
2001-04-01 00:00:00pages
713-22issue
4-6eissn
0531-5565issn
1873-6815pii
S0531556500002370journal_volume
36pub_type
杂志文章,评审abstract::Dietary restriction extends lifespan in a variety of organisms, but the key nutritional components driving this process and how they interact remain uncertain. In Drosophila, while a substantial body of research suggests that protein is the major dietary component affecting longevity, recent studies claim that carbohy...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2013.02.003
更新日期:2013-10-01 00:00:00
abstract::The aim of the present study was to compare the effects of water-based aerobic training and water-based resistance training on muscular strength and cardiorespiratory fitness in older women. Sixty-nine individuals were randomized into the following three groups: the water-based aerobic training (WA, n = 23) group, the...
journal_title:Experimental gerontology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.exger.2018.04.022
更新日期:2018-07-15 00:00:00
abstract::Delirium is an acute-onset syndrome that exacerbates patients' condition and significantly increases consequential morbidity and mortality. There is no comprehensive, cellular and tissue-level, pathophysiological theory. The melatonin hormone imbalance has been shown to be linked to circadian rhythms, sleep-wake cycle...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2015.09.007
更新日期:2015-12-01 00:00:00
abstract::SAMP8 mice exhibit multiple metabolic characteristics associated with age, and it is a suitable candidate for researching aging associated metabolic dysfunction. OBJECTIVES:We aimed to 1) explore how key metabolic markers will be altered in both liver and adipose tissue with aging in SAMP8 mice; and 2) how the combin...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2017.03.017
更新日期:2017-07-01 00:00:00
abstract:BACKGROUNDS:Elucidating the causal effects of common intermediate risk factors on the onset of age-related diseases is indispensable for developing prevention and intervention procedures. METHODS:We conducted two-stage time-to-event Mendelian randomization meta-analyses combining five large-scale longitudinal cohorts ...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2017.09.019
更新日期:2018-07-01 00:00:00
abstract::Declines in mobility with advancing age are often associated with a reduction in the use of lower leg muscles. We examined the influence of two interventions that involved neuromuscular electrical stimulation (NMES) applied to the triceps surae muscles on the mobility and muscle function of older adults. Thirty health...
journal_title:Experimental gerontology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.exger.2018.04.018
更新日期:2018-07-15 00:00:00
abstract::The intrinsic contractile properties of papillary muscles isolated from female Wistar rats during post-natal development were examined. In addition, the myocardial responsiveness to certain inotropic interventions was studied. In muscles from 60-day-old animals, the velocity of shortening was markedly greater than mus...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/0531-5565(82)90025-0
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To assess the 24-h endogenous secretory growth hormone (GH) profile and serum insulin-like growth factor-I (IGF-I) response to exogenous recombinant human growth hormone (rhGH) in a patient with Werner's syndrome. DESIGN:Blood sampling every 20 min for 24 h followed by three daily injections of growth hormon...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/0531-5565(96)00031-9
更新日期:1996-09-01 00:00:00
abstract::Advanced paternal age is associated with increased complications in pregnancy and genetic diseases in offspring. Oxidative stress is a major contributor to the damage accumulated in sperm during aging. Complex networks of antioxidants regulate reactive oxygen species (ROS) in the testis. While mounting evident shows t...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2016.08.012
更新日期:2016-11-01 00:00:00
abstract::Dystrophin-deficiency causes cardiomyopathies and shortens the life expectancy of Duchenne and Becker muscular dystrophy patients. Restoring Dystrophin expression in the heart by gene transfer is a promising avenue to explore as a therapy. Truncated Dystrophin gene constructs have been engineered and shown to alleviat...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2013.10.015
更新日期:2014-01-01 00:00:00
abstract::In young mice exposed to aerosol infection with Mycobacterium tuberculosis removal of the gammadelta T cell population by targeted gene disruption does not affect the expression of host resistance, but does influence the integrity of the early granulomatous response. The current study demonstrates that in aged gammade...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/s0531-5565(00)00199-6
更新日期:2001-02-01 00:00:00
abstract::Skeletal remodelling is a continuous process during life and is still active also in extreme senescence. In the elderly, bone resorption often prevails over bone formation, causing bone loss and fragility. Elderly subjects are exposed to the risk of fractures, and loss of self-sufficiency, if considering that the prox...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2007.06.013
更新日期:2008-02-01 00:00:00
abstract::The effect of age on brain muscarinic receptor density is unclear. Some in vivo neuroimaging studies have reported a large age-related reduction in muscarinic receptor density; however, others have reported increases or no change. The variability in these results most likely arises because of the heterogeneity of the ...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2004.10.002
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To explore the impact of diabetic peripheral neuropathy (DPN) on the recovery of older persons with diabetes mellitus (DM) after hip-fracture surgery. DESIGN, SETTING, PARTICIPANTS:Secondary data for this study came from a clinical trial on the effectiveness of a DM-specific care model for 176 ol...
journal_title:Experimental gerontology
pub_type: 临床试验,杂志文章
doi:10.1016/j.exger.2019.02.004
更新日期:2019-05-01 00:00:00
abstract:INTRODUCTION:Aging leads to poorer neuromuscular control that may impact mobility. However, the specific decades when these changes occur, and whether these time-based changes are sex-specific, are unclear. METHODS:Adults aged 20-82 years (N = 93, 51 females) walked six gait trials at their preferred speed over a 10-m...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2018.05.005
更新日期:2018-09-01 00:00:00
abstract::Type 2 diabetes is associated with progressive beta-cell failure manifest as a decline in insulin secretion and increasing hyperglycemia. A growing body of evidence suggests that beta-cell failure in type 2 diabetes correlates with the formation of pancreatic islet amyloid deposits, indicating that islet amyloid may h...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/s0531-5565(03)00004-4
更新日期:2003-04-01 00:00:00
abstract::Accumulation of altered proteins is the most common molecular symptom of ageing. Altered proteins are also associated with many age-related pathologies. Altered proteins are continuously produced but are normally selectively degraded by cellular proteases; their accumulation during ageing may be explained by either or...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2006.03.004
更新日期:2006-05-01 00:00:00
abstract::Diabetes mellitus (DM) is considered a risk factor for the development of Alzheimer disease (AD); however, how DM favors evolution of AD is still insufficiently understood. Hyperglycemia in DM is associated to an increase in mitochondrial reactive oxygen species (ROS) generation, as well as damage of hippocampal cells...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2014.08.008
更新日期:2014-10-01 00:00:00
abstract::The loss of bone mineral with aging and subsequent development of osteoporosis is a common problem in elderly women, and as life expectancy increases, in elderly men as well. Space flight also causes bone loss and could be a limiting factor for long duration missions, such as, a Mars expedition or extended occupation ...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/0531-5565(91)90011-a
更新日期:1991-01-01 00:00:00
abstract::The Tokyo Metropolitan Institute of Gerontology (TMIG) celebrates its 30th anniversary in 2002. Since its establishment, TMIG has been carrying out inter-disciplinary research on aging as a core institute in Japan and functions as a knowledge bank and a source for capable researchers of gerontology. The proportion of ...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/s0531-5565(02)00169-9
更新日期:2002-12-01 00:00:00
abstract::Mitochondrial superoxide production is an important source of reactive oxygen species in cells, and may cause or contribute to ageing and the diseases of ageing. Seven major sites of superoxide production in mammalian mitochondria are known and widely accepted. In descending order of maximum capacity they are the ubiq...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2010.01.003
更新日期:2010-08-01 00:00:00
abstract::Telomere length is considered as a biological marker for aging. It is expected that telomeres shorten with age and with conditions associated with oxidative stress and inflammation. Both are present in patients with chronic kidney disease (CKD) who have a very high cardiovascular risk. We investigated whether CKD dura...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2015.09.019
更新日期:2015-12-01 00:00:00
abstract::Alzheimer's disease is one of the most devastating neurodegenerative diseases. The exact cause of the disease is still not known although many scientists believe in the beta amyloid hypothesis which states that the accumulation of the amyloid peptide beta (Aβ) in brain is the initial cause which consequently leads to ...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2017.12.019
更新日期:2018-07-01 00:00:00
abstract::Rodent gerontology experiments should be carefully designed and correctly analyzed so as to provide the maximum amount of information for the minimum amount of work. There are five criteria for a "good" experimental design. These are applicable both to in vivo and in vitro experiments: (1) The experiment should be unb...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/s0531-5565(96)00032-0
更新日期:1997-01-01 00:00:00
abstract::This study aimed to analyze the effects of resistance training associated with testosterone administration in the neuromuscular junction (NMJ) postsynaptic region of different skeletal muscle types of aged rats. Wistar rats were divided into: SEI - 20-months-old control, SEF - 24-months-old control, T - 20-months-old ...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2017.08.018
更新日期:2017-11-01 00:00:00
abstract::Psychological stress has often been described as a feeling of being overwhelmed by the necessity of constant adjustment to an individual's changing environment. Stress affects people of all ages, but the lives of the elderly may particularly be affected. Major changes can cause anxiety leading to feelings of insecurit...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2014.12.003
更新日期:2015-08-01 00:00:00
abstract::A mathematical model of cellular metabolism is used to relate the rates of cell division and waste production to the concentrations of oxygen and glucose in the medium in which a normal diploid cell culture is grown. The metabolic model in tandem with an earlier waste-content model based on the waste-product theory of...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/0531-5565(91)90073-u
更新日期:1991-01-01 00:00:00
abstract::Aging is associated with a progressive decline of muscle mass, strength, and quality, a condition described as sarcopenia of aging. Despite the significance of skeletal muscle atrophy, the mechanisms responsible for the deterioration of muscle performance are only partially understood. The purpose of this review is to...
journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2008.05.003
更新日期:2009-01-01 00:00:00
abstract::Ascorbic acid decreases from age-group I to II in Kidney, skeletal muscle, and increases in the Pancreas of female. There is no significant change in the Pancreas of male toad. There is an increase in the ascorbic acid content from age group II to III except in the Pancreas of females, where there is a decline of the ...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/0531-5565(84)90011-1
更新日期:1984-01-01 00:00:00
abstract::Apolipoprotein E knockout (apoE-KO) mice have been utilized for decades as a model of atherosclerosis. However, in addition to atherosclerosis, apoE-KO mice develop extensive cutaneous xanthomatosis, accelerated skin aging and frailty when fed a high fat diet. Granzyme B (GrB) is a pro-apoptotic serine protease that h...
journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2011.02.004
更新日期:2011-06-01 00:00:00