Abstract:
PURPOSE:The purpose of this study was to investigate whether or not clustering of biological coronary heart disease (CHD) risk factors exists and to investigate the longitudinal relationship between lifestyle parameters (dietary intake, daily physical activity, smoking behaviour, alcohol consumption) and a biological CHD risk factor clustering score. This was defined as belonging to one or more gender specific 'high risk' quartiles for the following CHD risk factors: ratio between total serum cholesterol and high density lipoprotein cholesterol (TC:HDL), mean arterial blood pressure (MABP), body fatness [sum of skinfolds (SSF)], and cardiopulmonary fitness (VO2-max). METHODS:The data were derived from the Amsterdam Growth and Health Study, an observational longitudinal study in which six repeated measurements were carried out over a period of 15 years covering adolescence and young adulthood. The longitudinal relationships were analysed with generalized estimating equations. RESULTS:The results showed significant clustering for the TC:HDL ratio, SSF, and VO(2)-max. MABP was not significantly associated with the other CHD risk factors. Daily physical activity and alcohol consumption (only for males) were both inversely related to the clustering score. None of the other lifestyle parameters showed significant relationships with the clustering score. CONCLUSIONS:Based on this small longitudinal study, it can be stated that during adolescence and young adulthood both daily physical activity and alcohol consumption were related to a healthy CHD risk profile.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Twisk JW,Kemper HC,Van Mechelen W,Post GBdoi
10.1016/s1047-2797(00)00202-7keywords:
subject
Has Abstractpub_date
2001-04-01 00:00:00pages
157-65issue
3eissn
1047-2797issn
1873-2585pii
S1047-2797(00)00202-7journal_volume
11pub_type
杂志文章abstract:PURPOSE:Gastroesophageal reflux disease is an important and increasingly common condition. Both overweight and high fat food consumption have been implicated as causes of reflux disease. We examined the relationship of overweight, high dietary fat intake, and other factors with reflux disease hospitalization. METHODS:...
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
pub_type: 杂志文章,meta分析
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
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pub_type: 杂志文章,多中心研究
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更新日期:2001-07-01 00:00:00
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更新日期:2010-04-01 00:00:00
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
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更新日期:2006-10-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2007-10-01 00:00:00
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更新日期:1999-02-01 00:00:00
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更新日期:2021-01-01 00:00:00
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journal_title:Annals of epidemiology
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更新日期:2011-06-01 00:00:00
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journal_title:Annals of epidemiology
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更新日期:2014-12-01 00:00:00
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
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更新日期:2019-08-01 00:00:00