Quantification and in situ localization of MCP-1 mRNA and its relation to the immune response of renal cell carcinoma.

abstract：:Candida albicans is an opportunistic fungal pathogen that colonizes human gastro-intestinal mucosal tissues. Its effect on the immune response in intestinal epithelial cells and on the intestinal mucosal barrier are not yet fully understood. In this study, we investigated Caco-2 cells, a monolayer model of intestinal ...

journal_title：Cytokine

authors： Mao X,Qiu X,Jiao C,Lu M,Zhao X,Li X,Li J,Ma J,Zhang H

更新日期：2020-02-01 00:00:00

abstract：:The evolution of malignant cells implies an increase in oncogenic fitness of cells which arises in active and reciprocal interaction with the tumor microenvironment. The mechanisms facilitating the adaptive evolution of cancer cells involve clonal selection of cancer cells, in a direction of increased adaptive potenti...

journal_title：Cytokine

authors： Todorović-Raković N

更新日期：2021-01-25 00:00:00

abstract：:The burst formation from human and murine burst forming unit-erythroid (BFU-E) requires the presence of erythropoietin (Epo) in semi-solid cultures of bone marrow cells. A number of haematopoietic factors are described that increase the burst number: interleukin 3 (IL-3), stem cell factor (SCF), granulocyte-macrophage...

journal_title：Cytokine

authors： Rodriguez MH,Arnaud S,Geay T,Mouchiroud G,Grasset MF,Blanchet JP

更新日期：1998-08-01 00:00:00

abstract：:Kawasaki disease is a multi-system vasculitis and a primary cause of acquired heart disease among children. Genetic factors may increase susceptibility to Kawasaki disease. TBXA2R is a G-protein-coupled receptor that participates in tissue inflammation and is associated with susceptibility to several diseases, but its...

journal_title：Cytokine

authors： Che D,Pi L,Xu Y,Fu L,Zhou H,Wang Z,Huang P,Zhang L,Gu X

更新日期：2018-11-01 00:00:00

abstract：:Antibiotic therapy is only moderately efficacious for bovine Staphylococcus aureus mastitis. We have used recombinant bovine cytokines to activate the natural host defenses, to prevent and treat bovine mastitis. Uninfected mammary glands infused with GM-CSF or IL-2 increased the percentage of phagocytic cells in the m...

journal_title：Cytokine

authors： Daley M,Williams T,Coyle P,Furda G,Dougherty R,Hayes P

更新日期：1993-05-01 00:00:00

abstract：:We examined seasonal differences in whole blood cytokine production after endotoxin (LPS) stimulation in 17 healthy individuals from an urban area having normal sleep/wakefulness pattern. We used 500 pg/ml of LPS for incubation period of 4 h to stimulate 100 microl of whole blood of the same subjects in June, Septembe...

journal_title：Cytokine

authors： Myrianthefs P,Karatzas S,Venetsanou K,Grouzi E,Evagelopoulou P,Boutzouka E,Fildissis G,Spiliotopoulou I,Baltopoulos G

更新日期：2003-12-21 00:00:00

abstract：:This study investigated changes in the myokines IL-1β, IL-6, and TNF-α, as well as HSP72, after endurance training and after a session of downhill running. Twenty-eight rats were allocated to four different groups: 1. Eight weeks of endurance training at 65-70% VO2max (Trained); 2. Endurance training and a single sess...

journal_title：Cytokine

authors： Isanejad A,Saraf ZH,Mahdavi M,Gharakhanlou R,Shamsi MM,Paulsen G

更新日期：2015-06-01 00:00:00

abstract：:We evaluated the spontaneous IL17, IFNgamma and IL10 production by peripheral blood mononuclear cells from patients affected by clinically isolated syndromes (CIS) suggestive of multiple sclerosis (MS) both in acute phase and in remission, relapsing remitting MS (RRMS) both in relapse and in remission, not-relapsing s...

journal_title：Cytokine

authors： Frisullo G,Nociti V,Iorio R,Patanella AK,Marti A,Caggiula M,Mirabella M,Tonali PA,Batocchi AP

更新日期：2008-10-01 00:00:00

abstract：:During the quarter of a century since TNF was isolated, much knowledge has been gained of the identity of other ligands besides TNF in the TNF cytokine family, and of the proximal signaling molecules that these ligands activate. The numerous laboratories contributing to this advance have approached TNF research from v...

journal_title：Cytokine

authors： Wallach D

更新日期：2013-09-01 00:00:00

abstract：:Granulocyte colony-stimulating factor (G-CSF) is the major cytokine involved in the control of neutrophil development. G-CSF activates the special receptor, the G-CSF receptor (GCSF-R), which subsequently triggers multiple signaling events. To obtain more interactive molecules with GCSF-R and to further understand the...

journal_title：Cytokine

authors： Yuan X,Shan Y,Zhao Z,Chen J,Cong Y

更新日期：2006-02-21 00:00:00

abstract：:Elevated levels of the cytokine IL-13 has been found to be associated with autoimmune diseases, including Sjögren's Syndrome. However, whether IL-13 plays a causative role in disease development is not known and cannot be easily studied in humans. Our previous work has shown that levels of IL-13 are elevated in Id3 kn...

journal_title：Cytokine

authors： Belle I,Mahlios J,McKenzie A,Zhuang Y

更新日期：2014-10-01 00:00:00

abstract：:Although immune responses following soft-tissue trauma-hemorrhage are markedly different in young (6-8 weeks) and aged (18-20 months) mice, it remains unknown if there are any differences in immune responses in middle-aged and young mice following bone fracture, soft-tissue trauma-hemorrhage (Fx-TH). To study this, yo...

journal_title：Cytokine

authors： Kang SC,Matsutani T,Choudhry MA,Schwacha MG,Rue LW,Bland KI,Chaudry IH

更新日期：2004-06-07 00:00:00

abstract：:The aim of this research was to assess the relationship between plasma adiponectin, leptin, resistin, tumor necrosis factor alpha (TNF-α) levels and echocardiographic parameters of ventricular remodeling in patients with coronary artery disease, without acute myocardial infarction. The study population consisted of 49...

journal_title：Cytokine

authors： Farcaş AD,Rusu A,Stoia MA,Vida-Simiti LA

更新日期：2018-03-01 00:00:00

abstract：:Our aim was to explore the putative beneficial effects of low-to-moderate intensity exercise training program in patients with irritable bowel syndrome (IBS). This study evaluated the changes in blood oxidative stress status, inflammatory biomarkers and IBS severity symptoms following 24 weeks of moderate aerobic exer...

journal_title：Cytokine

authors： Hajizadeh Maleki B,Tartibian B,Mooren FC,FitzGerald LZ,Krüger K,Chehrazi M,Malandish A

更新日期：2018-02-01 00:00:00

abstract：:L-buthionine-S,R-sulfoximine (BSO), an inhibitor of GSH synthesis, decreased IL-1 beta-induced nitrite release in rat islets and purified rat beta cells, nitrite formation and iNOS gene promoter activity in insulinoma cells, and iNOS mRNA expression in rat islets. The thiol depletor diethyl maleate (DEM) and an inhibi...

journal_title：Cytokine

authors： Nikulina MA,Andersen HU,Karlsen AE,Darville MI,Eizirik DL,Mandrup-Poulsen T

更新日期：2000-09-01 00:00:00

abstract：:IFNγ is a potent activator and IL-10 a powerful inhibitor of macrophage functions. However, neither all cellular functions are enhanced by IFNγ nor IL-10 inhibits all cellular responses. Thus, FcγRs-mediated phagocytosis in monocyte-derived macrophages (MDM) increases after IL-10 treatment, and decreases after treatme...

journal_title：Cytokine

authors： Frausto-Del-Río D,Soto-Cruz I,Garay-Canales C,Ambriz X,Soldevila G,Carretero-Ortega J,Vázquez-Prado J,Ortega E

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:This study evaluates the potential of gingival crevicular fluid and serum cytokines as HIV stage biomarkers. METHODS:Gingival crevicular fluid (GCF) and serum samples from 78 HIV-positive adult male subjects (cases) and 39 HIV-negative male subjects (controls) from Mexico were examined for 17 cytokines using...

journal_title：Cytokine

authors： Elizondo JE,Rocha-Pizaña MD,Treviño AC,Violant D,Álvarez MM,Rivas-Estilla AM

更新日期：2017-03-01 00:00:00

abstract：:The in vivo influence of recombinant human erythropoietin (rhEpo) and iron on human neutrophil (PMN) antimicrobial function was assessed. A total of 21 preterm infants were randomized to receive either 200 U/kg/other day of rHuEPO+12 mg/kg/day of iron (EPO+high Fe, seven infants) or 200 U/kg/other day of rhEPO+4 mg/kg...

journal_title：Cytokine

authors： Soubasi V,Roilides E,Tsantali C,Mussafiris K,Tsakiris D,Kremenopoulos G

更新日期：1999-01-01 00:00:00

abstract：:Burn injury is associated with profound inflammation and activation of the innate immune system involving gammadelta T-cells. Similarly, Toll-like receptors (TLR) are associated with activation of the innate immune response; however, it is unclear whether TLR expression is altered in gammadelta T-cells after major bur...

journal_title：Cytokine

authors： Schwacha MG,Daniel T

更新日期：2008-12-01 00:00:00

abstract：:The pathogenesis of rheumatoid arthritis (RA) and psoriatic arthritis (PsA) involves an abnormal chemokine regulation. The chemokine receptor CCR4 is necessary for T cell migration to the skin. We, therefore, studied if CCR4 and its ligand macrophage-derived chemokine (MDC/CCL22) could participate in spreading the dis...

journal_title：Cytokine

authors： Flytlie HA,Hvid M,Lindgreen E,Kofod-Olsen E,Petersen EL,Jørgensen A,Deleuran M,Vestergaard C,Deleuran B

更新日期：2010-01-01 00:00:00

abstract：:Published data on the association between microRNA-146a (miR-146a) G/C polymorphism and cancer susceptibility are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. A total of 23 studies including 10,585 cases and 12,183 controls were used in the meta-analysis. Overal...

journal_title：Cytokine

authors： Qiu LX,He J,Wang MY,Zhang RX,Shi TY,Zhu ML,Mao C,Sun S,Lv FF,Zheng CL,Zhu XD

更新日期：2011-12-01 00:00:00

abstract：:Three molecules, interleukin 1 (IL-1) receptor I (IL-1RI), IL-1 receptor II (IL-1RII or decoy) and IL-1 receptor accessory protein (IL-1R AcP or IL-1RIII), are involved in IL-1 binding and signal transduction. In addition, three homologous genes (T1/ST2, MyD88 and rsc786) have been identified. Expression of the signal...

journal_title：Cytokine

authors： Saccani S,Polentarutti N,Penton-Rol G,Sims JE,Mantovani A

更新日期：1998-10-01 00:00:00

abstract：:IL-1 family members regulate innate immune responses, are produced by gestation-associated tissues, and have a role in healthy and adverse pregnancy outcomes. To better understand their role at the materno-fetal interface we used a human tissue explant model to map lipopolysaccharide (LPS)-stimulated production of IL-...

journal_title：Cytokine

authors： Scott LM,Bryant AH,Rees A,Down B,Jones RH,Thornton CA

更新日期：2017-11-01 00:00:00

abstract：:Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is characterized by severe worsening dyspnea of unknown etiology and high mortality without effective treatment. Recently, direct hemoperfusion with polymyxin B (PMX)-immobilized fiber cartridge (PMX-DHP) has been reported to improve pulmonary oxygenation an...

journal_title：Cytokine

authors： Oishi K,Mimura-Kimura Y,Miyasho T,Aoe K,Ogata Y,Katayama H,Murata Y,Ueoka H,Matsumoto T,Mimura Y

更新日期：2013-01-01 00:00:00

abstract：:Injection of tumour necrosis factor (TNF) in animals causes severe liver cell toxicity, especially when D-(+)-galactosamine (GalN) is co-administered. After challenge with TNF/GalN, serum complement activity (CH50 and APCH50) decreased dramatically, suggesting strong activation of both the classical and the alternativ...

journal_title：Cytokine

authors： Libert C,Wielockx B,Grijalba B,Van Molle W,Kremmer E,Colten HR,Fiers W,Brouckaert P

更新日期：1999-08-01 00:00:00

abstract：:HIV infection is associated with chronic inflammation in both non-treated and treated patients. TLR-dependent mechanisms are strongly involved in the maintenance of this inflammation. Indeed, the residual replication of HIV, the potential viral co-infections, or the products issued from microbial translocation provide...

journal_title：Cytokine

authors： Leite Pereira A,Tchitchek N,Marcos Lopez E,Lambotte O,Le Grand R,Cosma A

更新日期：2018-11-01 00:00:00

abstract：:Stem cell therapy is a promising strategy for recovering of injured cardiac tissue after acute myocardial infarction. The effects promoted by preventive physical training, beneficial for regeneration, are not yet understood on stem cell homing. In the present study, we evaluated the effect of preventive physical train...

journal_title：Cytokine

authors： Schaun MI,Kristochek M,Dias LD,Peres TR,Lehnen AM,Irigoyen MC,Markoski MM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Adiponectin is an anti-atherogenic insulin-sensitizer hormone whose plasma concentration is lower in patients with metabolic syndrome (MS). Visceral adiposity, including epicardial adipose tissue (EAT), is closely related to the development of MS and coronary artery disease (CAD). We sought to study whether ...

journal_title：Cytokine

authors： Teijeira-Fernandez E,Eiras S,Shamagian LG,Somoza AS,Delgado C,Gonzalez-Juanatey JR

更新日期：2011-05-01 00:00:00

abstract：RATIONALE:Sarcoidosis is an idiopathic granulomatous disorder with heterogeneous clinical manifestations and variable prognosis. Monitoring disease activity is important to identify patients requiring treatment. Several cytokines have previously been shown to be elevated in the serum of patients with sarcoidosis and ma...

journal_title：Cytokine

authors： Geyer AI,Kraus T,Roberts M,Wisnivesky J,Eber CD,Hiensch R,Moran TM

更新日期：2013-10-01 00:00:00

abstract：:In order to understand the cellular disease mechanisms of osteoarthritic cartilage degeneration it is of primary importance to understand both the anabolic and the catabolic processes going on in parallel in the diseased tissue. In this study, we have applied cDNA-array technology (Clontech) to study gene expression p...

journal_title：Cytokine

authors： Aigner T,McKenna L,Zien A,Fan Z,Gebhard PM,Zimmer R

更新日期：2005-08-07 00:00:00