Expression of vascular endothelial growth factor in human monocyte/macrophages stimulated with lipopolysaccharide.

abstract：:Factor VII is a vitamin K-dependent zymogen that plays a key role in the initiation of the extrinsic pathway. A severe factor VII deficiency was identified in a 45-year old male whose plasma factor VII antigen was less than 60 ng/ml and expressed 5.2% of normal factor VII activity. DNA sequence analysis of the patient...

journal_title：Thrombosis and haemostasis

authors： Katsumi A,Matsushita T,Yamazaki T,Sugiura I,Kojima T,Saito H

更新日期：2000-02-01 00:00:00

abstract：:Long-term evidence supports a clustering of cardiovascular events in the early morning and smaller mechanistic studies in aspirin-treated patients have shown increased platelet reactivity at the end of the dosing interval. Comparative pharmacodynamic analyses for different adenosine diphosphate (ADP) receptor inhibito...

journal_title：Thrombosis and haemostasis

authors： Freynhofer MK,Hein-Rothweiler R,Haller PM,Aradi D,Dézsi DA,Gross L,Orban M,Trenk D,Geisler T,Huczek Z,Toth-Gayor GG,Massberg S,Huber K,Sibbing D

更新日期：2019-04-01 00:00:00

abstract：:Abnormal antithrombin III (AT III) was found in the plasma of a 31-year-old female who suffered from recurrent thrombotic episodes. Heparin cofactor activity was 28% of normal and undetectable when measured by inhibition of thrombin and factor Xa (F.Xa), while both progressive antithrombin and antifactor Xa activities...

journal_title：Thrombosis and haemostasis

authors： Okajima K,Ueyama H,Hashimoto Y,Sasaki Y,Matsumoto K,Okabe H,Inoue M,Araki S,Takatsuki K

更新日期：1989-02-28 00:00:00

abstract：:Heme oxygenase-1 (HO-1) decreases apoptosis, inflammation and oxidative stress. The aim of the study was to investigate the effects of intracoronary infusion of allogenic bone marrow cells (BMC) overexpressing HO-1 in the porcine model of myocardial infarction (MI). MI was produced by balloon occlusion of a coronary a...

journal_title：Thrombosis and haemostasis

authors： Wojakowski W,Tendera M,Cybulski W,Zuba-Surma EK,Szade K,Florczyk U,Kozakowska M,Szymula A,Krzych L,Paslawska U,Paslawski R,Milewski K,Buszman PP,Nabialek E,Kuczmik W,Janiszewski A,Dziegiel P,Buszman PE,Józkowicz A,D

更新日期：2012-09-01 00:00:00

abstract：:Stress may counteract responses to antiplatelet drug treatment. We investigated if adding clopidogrel to aspirin treatment could attenutate stress-induced platelet activation and myocardial ischemia in patients with coronary artery disease (CAD). Thirty-one male patients with documented CAD-treated with aspirin (75-16...

journal_title：Thrombosis and haemostasis

authors： Perneby C,Wallén NH,Hofman-Bang C,Tornvall P,Ivert T,Li N,Hjemdahl P

更新日期：2007-12-01 00:00:00

abstract：:In 7 healthy volunteers, formation of thrombin (represented by fibrinopeptide A (FPA) generation, alpha-granule release (represented by beta-thromboglobulin [beta TG] release) and the generation of thromboxane B2 (TxB2) were measured in vivo in blood emerging from a template bleeding time incision. At the site of plug...

journal_title：Thrombosis and haemostasis

authors： Kyrle PA,Westwick J,Scully MF,Kakkar VV,Lewis GP

更新日期：1987-02-03 00:00:00

abstract：:An algal sulfated galactan has high anticoagulant and antithrombotic activities. Its serpin-dependent anticoagulant action is due to promoting thrombin and factor (F)Xa inhibition by antithrombin and heparin cofactor II. Here, we evaluated the anticoagulant effect of the algal sulfated galactan using serpin-free plasm...

journal_title：Thrombosis and haemostasis

authors： Glauser BF,Rezende RM,Melo FR,Pereira MS,Francischetti IM,Monteiro RQ,Rezaie AR,Mourão PA

更新日期：2009-12-01 00:00:00

abstract：:Underlying disorders of the coagulation system such as inhibitor deficiencies or decreased fibrinolysis are common in patients suffering from venous thrombosis. They may lead to the necessity of a lifelong prophylaxis. Prompt diagnosis is obviously to the patients benefit. We investigated 22 patients suffering from ve...

journal_title：Thrombosis and haemostasis

authors： Reiter W,Ehrensberger H,Steinbrückner B,Keller F

更新日期：1995-08-01 00:00:00

abstract：:We investigated plasma activated factor VII (FVIIa) levels in uremic patients (nondialysis group: n = 38; dialysis group: n = 36) and healthy controls (n = 32). We also measured the plasma levels of thrombomodulin (an indicator of endothelial cell injury) and tissue factor. Plasma FVIIa showed a marked increase in the...

journal_title：Thrombosis and haemostasis

authors： Kario K,Matsuo T,Matsuo M,Koide M,Yamada T,Nakamura S,Sakata T,Kato H,Miyata T

更新日期：1995-05-01 00:00:00

abstract：:We have investigated the effect of a new Leu196Pro mutation, identified in the MIDAS-like domain of the beta3 integrin subunit in a patient with type II Glanzmann thrombasthenia, on beta3 integrin receptor function. Expression of the mutant beta3Pro196 subunit in CHO cells, either associated with recombinant human alp...

journal_title：Thrombosis and haemostasis

authors： Morel-Kopp MC,Melchior C,Chen P,Ammerlaan W,Lecompte T,Kaplan C,Kieffer N

更新日期：2001-12-01 00:00:00

abstract：:Current data suggests that the risk of venous thromboembolism (VTE) in patients with non-Hodgkin lymphoma (NHL) is comparable to that observed in patients with solid tumours, although more robust confirmatory analyses are required. With that in mind, we investigated the occurrence of VTE in a pooled analysis of 12 "Fo...

journal_title：Thrombosis and haemostasis

authors： Santi RM,Ceccarelli M,Bernocco E,Monagheddu C,Evangelista A,Valeri F,Monaco F,Vitolo U,Cortelazzo S,Cabras MG,Spina M,Baldini L,Boccomini C,Chiappella A,Bari A,Luminari S,Visco C,Calabrese M,Limberti G,Levis A,Con

更新日期：2017-04-27 00:00:00

abstract：:Recent experiments have shown that a preparation of PPSB (factor IX concentrate) derived form beta PL/UV treated plasma was not infectious in chimpanzees with respect to hepatitis B and non-A, non-B. To answer the question whether the beta PL/UV treatment influences the tolerance and efficacy of the PPSB-concentrate, ...

journal_title：Thrombosis and haemostasis

authors： Stephan W,Kotitschke R,Prince AM,Brotman B

更新日期：1981-08-28 00:00:00

abstract：:Worldwide, haemophilia is the most common hereditary bleeding disorder. The incidence of haemophilia B, however, is considerably less than haemophilia A and consequently appears to have received less attention in the research literature. This article aims to summarise the available evidence documenting the patient and...

journal_title：Thrombosis and haemostasis

authors： Gater A,Thomson TA,Strandberg-Larsen M

更新日期：2011-09-01 00:00:00

abstract：:Atrial fibrillation (AF) is a common complication of coronary artery bypass grafting (CABG). We sought to determine the diagnostic validity of plasma biomarkers of i) inflammation (marked by interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hs-CRP]), ii) extracellular matrix remodelling (matrix metalloprot...

journal_title：Thrombosis and haemostasis

authors： Kaireviciute D,Blann AD,Balakrishnan B,Lane DA,Patel JV,Uzdavinys G,Norkunas G,Kalinauskas G,Sirvydis V,Aidietis A,Lip GY

更新日期：2010-07-01 00:00:00

abstract：:A collaborative study has been organised by NIBSC to examine the performance of FIXa assays between laboratories, and to investigate the need for a standard. Ampoules of 3 materials, one monocomponent concentrate (coded C) and 2 different preparations of purified human FIXa (one proposed reference preparation, coded A...

journal_title：Thrombosis and haemostasis

authors： Gray E,Walker D,Heath A,Barrowcliffe TW

更新日期：1996-12-01 00:00:00

abstract：:Growing evidence indicates that rheumatoid arthritis (RA) is associated with an increased risk for thromboembolic cardiovascular events. We investigated thrombin generation profiles in RA patients and their dependence on plasma factor/inhibitor composition. Plasma factor (F) compositions (II, V, VII, VIII, IX, X), ant...

journal_title：Thrombosis and haemostasis

authors： Undas A,Gissel M,Kwasny-Krochin B,Gluszko P,Mann KG,Brummel-Ziedins KE

更新日期：2010-08-01 00:00:00

abstract：:Pulmonary embolism (PE) may encompass a wide spectrum of severity. To determine whether clinical findings, D-dimer (DD) concentration, and deep vein thrombosis (DVT) shown by lower-limb venous compression ultrasonography (US) might predict the scintigraphic extent of PE, we studied 104 hemodynamically stable consecuti...

journal_title：Thrombosis and haemostasis

authors： Galle C,Papazyan JP,Miron MJ,Slosman D,Bounameaux H,Perrier A

更新日期：2001-11-01 00:00:00

abstract：:We studied the role of various markers of lipid metabolism, hemostasis and inflammation in a two year follow-up of 3,000 patients with angina pectoris, during which time 106 patients experienced myocardial infarction or sudden coronary death. Low levels of high density lipoprotein (HDL) cholesterol and of apolipoprote...

journal_title：Thrombosis and haemostasis

authors： Bolibar I,von Eckardstein A,Assmann G,Thompson S,ECAT Angina Pectoris Study Group. European Concerted Action on Thrombosis and Disabilities.

更新日期：2000-12-01 00:00:00

abstract：:Inherited thrombophilic states are associated with an increased risk for deep vein thrombosis (DVT), but whether they are also risk factors for superficial vein thrombosis (SVT) is uncertain. We assessed the risk conferred by inherited thrombophilic states in patients with a first episode of SVT in whom the coexistenc...

journal_title：Thrombosis and haemostasis

authors： Martinelli I,Cattaneo M,Taioli E,De Stefano V,Chiusolo P,Mannucci PM

更新日期：1999-10-01 00:00:00

abstract：:Fresh retracted clots are known to be poorly lysable by fibrinolytic agents. We have studied whether lysis of retracted clots could be enhanced by bulk transport in comparison to pure diffusion of plasma containing urokinase (400 IU/ml) into the clots. Cylindrical retracted blood clots were occlusively glued by a poly...

journal_title：Thrombosis and haemostasis

authors： Blinc A,Keber D,Lahajnar G,Stegnar M,Zidansek A,Demsar F

更新日期：1992-12-07 00:00:00

abstract：:Normal adults have very few circulating endothelial cells (CECs) in their blood, but increased levels have been shown in association with conditions associated with endothelial damage such as myocardial infarction and stroke. As atrial fibrillation (AF) is associated with a hypercoagulable state and abnormalities of p...

journal_title：Thrombosis and haemostasis

authors： Freestone B,Lip GY,Chong AY,Nadar S,Lee KW,Blann AD

更新日期：2005-10-01 00:00:00

abstract：:We analyzed the protein C gene (PROC) with the denaturing gradient gel electrophoresis (DGGE) scanning strategy in a series of 129 patients with suspected protein C (PC) deficiency (93 with low plasma PC levels and 36 with borderline level). At least one sequence variation was found in 104 of the 129 patients. Thirty-...

journal_title：Thrombosis and haemostasis

authors： Alhenc-Gelas M,Gandrille S,Aubry ML,Aiach M

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of a fixed dose of recombinant activated factor VII (rFVIIa; NovoSeven) in the home setting for mild to moderately severe joint, muscle; and mucocutaneous bleeding episodes in patients with haemophilia A or B with inhibitors. DESIGN:Multicentre, open-label, single arm, phase...

journal_title：Thrombosis and haemostasis

authors： Key NS,Aledort LM,Beardsley D,Cooper HA,Davignon G,Ewenstein BM,Gilchrist GS,Gill JC,Glader B,Hoots WK,Kisker CT,Lusher JM,Rosenfield CG,Shapiro AD,Smith H,Taft E

更新日期：1998-12-01 00:00:00

abstract：:Vessel wall matrix changes occur after injury, although this has not been well studied in the venous system. This study tested the hypothesis that the thrombus dictates the vein wall response and vein wall damage is directly related to the duration of thrombus contact. To determine the injury response over time, rats ...

journal_title：Thrombosis and haemostasis

authors： Henke PK,Varma MR,Moaveni DK,Dewyer NA,Moore AJ,Lynch EM,Longo C,Deatrick CB,Kunkel SL,Upchurch GR Jr,Wakefield TW

更新日期：2007-11-01 00:00:00

abstract：:Venous thromboembolic (VTE) complications in children and adolescents with acute lymphoblastic leukaemia (ALL) and T or B cell lymphoblastic lymphoma (T/B cell LL) can result not only in life-threatening acute complications but also contribute to significant long-term sequelae. The PREVAPIX-ALL study is an open-label ...

journal_title：Thrombosis and haemostasis

authors： O'Brien SH,Li D,Mitchell LG,Hess T,Zee P,Yee DL,Newburger JW,Sung L,Rodriguez V

更新日期：2019-05-01 00:00:00

abstract：:The structural determinants of lipopolysaccharide required for the induction of tissue factor in human umbilical vein endothelial cells were studied. Intact lipid A was essential for the induction of tissue factor whereas the incomplete lipid A precursors lipid IVA and lipid X, as well as monophosphoryl lipid A and ac...

journal_title：Thrombosis and haemostasis

authors： Moldow CF,Bach RR,Staskus K,Rick PD

更新日期：1993-10-18 00:00:00

abstract：:Although sepsis-induced release of nitric oxide (NO) is known to have an antithrombotic effect, it is unknown if NO exerts this same effect under physiological conditions. We have there-fore attempted to determine whether or not NO protects against thrombus formation in normal Wistar rats injected with various amounts...

journal_title：Thrombosis and haemostasis

authors： Asakura H,Okudaira M,Ontachi Y,Mizutani T,Omote M,Yoshida T,Kaneda M,Yamazaki M,Morishita E,Takami A,Miyamoto K,Nakao S

更新日期：2004-01-01 00:00:00

abstract：:Recently, numerous studies have suggested an association between factor XII (FXII) deficiency and recurrent pregnancy losses, and between autoantibodies to FXII and recurrent pregnancy losses. Autoantibodies to FXII rather than FXII deficiency may be a risk factor for recurrent pregnancy losses. To know the pathogenes...

journal_title：Thrombosis and haemostasis

authors： Inomo A,Sugi T,Fujita Y,Matsubayashi H,Izumi S,Mikami M

更新日期：2008-02-01 00:00:00

abstract：:Type I von Willebrand disease (vWD) Vicenza is a rare variant with autosomal dominant transmission, characterized by the presence of supranormal von Willebrand factor (vWF) multimers in plasma, similar to those normally found in endothelial cells and megakaryocytes. The patients have very low levels of plasma vWF cont...

journal_title：Thrombosis and haemostasis

authors： Randi AM,Sacchi E,Castaman GC,Rodeghiero F,Mannucci PM

更新日期：1993-02-01 00:00:00

abstract：:Many of the agonists that cause platelet activation are thought to do so by interacting with G protein-coupled receptors on the platelet surface. By activating heterotrimeric G proteins, these receptors evoke shape change, granule secretion and platelet aggregation. This review provides a brief overview of these event...

journal_title：Thrombosis and haemostasis

authors： Brass LF,Manning DR,Cichowski K,Abrams CS

更新日期：1997-07-01 00:00:00