Orofacial viral infections in the immunocompromised host.

abstract：:ABCG2 is a multidrug cellular transport protein that is associated with resistance to certain treatments in patients, particularly anticancer treatment. The tumor-protective properties of ABCG2 expression are reported to be a feature of a subset of stem cell-like tumor cells. While protection against chemotherapy has ...

journal_title：Oncology reports

authors： Zoernig I,Ziegelmeier C,Lahrmann B,Grabe N,Jäger D,Halama N

更新日期：2013-05-01 00:00:00

abstract：:The clinical significance of NK-like T CD3+/CD16+CD56+ cells in chronic lymphocytic leukemia (CLL) is still a subject of controversy. There are few previous descriptions that this cell population can be qualitatively or quantitatively deficient in CLL patients. In the present study we investigated the clinical value o...

journal_title：Oncology reports

authors： Bojarska-Junak A,Hus I,Sieklucka M,Wasik-Szczepanek E,Mazurkiewicz T,Polak P,Dmoszynska A,Rolinski J

更新日期：2010-09-01 00:00:00

abstract：:Pancreatic cancer is usually diagnosed in the advanced stages and is sensitive to only few therapies. The forkhead box L1 (FOXL1) and protein phosphatase 2A (PP2A) have been recognized to be tumor suppressive in human pancreatic cancers. In the present study, we co-expressed the two tumor suppressive molecules with a ...

journal_title：Oncology reports

authors： Li Y,Yu D,Sheng W,Song H,Li Y,Dong M

更新日期：2016-04-01 00:00:00

abstract：:In the present study, the preliminary results of the first stereotactic body radiosurgery (SRS) experience with volumetric intensity modulated arc therapy (VMAT) in oligometastatic breast and recurrent gynecological tumors (OBRGT) are reported in terms of feasibility, toxicity and efficacy. Patients were treated in a ...

journal_title：Oncology reports

authors： Macchia G,Deodato F,Cilla S,Torre G,Corrado G,Legge F,Gambacorta MA,Tagliaferri L,Mignogna S,Scambia G,Valentini V,Morganti AG,Ferrandina G

更新日期：2014-11-01 00:00:00

abstract：:We radiographically evaluated the response of primary lesions to chemotherapy in 101 patients with inoperable advanced gastric cancer. The median survival time in the 50 responders (49.5%) was 379 days, as compared with only 210 days in the 51 non-responders (50.1%) (p<0. 001). Morphologic changes of the gastric mucos...

journal_title：Oncology reports

authors： Yamazaki I,Koizumi W,Kondo I,Saigenji K

更新日期：2000-11-01 00:00:00

abstract：:Invasiveness and metastasis may seriously affect the prognosis of small cell lung cancer (SCLC). In the present study, we analyzed the effects and inherent mechanisms of action of polysialic acid-modified neural cell adhesion molecule (NCAM) on the invasive and metastatic potential of SCLC. Gene transfection and short...

journal_title：Oncology reports

authors： Gong L,Zhou X,Yang J,Jiang Y,Yang H

更新日期：2017-01-01 00:00:00

abstract：:Laryngeal squamous cell carcinoma (LSCC) is a common cancer of the upper respiratory tract. The cytogenetic and molecular events involved in the pathogenesis of LSCC are not well understood. In this study, a combined strategy of conventional cytogenetics, fluorescent in situ hybridization (FISH) and microsatellite pol...

journal_title：Oncology reports

authors： Kang N,Li F,Fu W,Zhang J,Sun K

更新日期：2007-12-01 00:00:00

abstract：:Progesterone has a potential protective effect against ovarian carcinoma induced by estrogen. Progesterone is also known to cause apoptosis while tamoxifen induces growth arrest. Therefore, we attempted to determine whether combined treatment with progesterone and tamoxifen has a sy...

journal_title：Oncology reports

authors： Lee JY,Shin JY,Kim HS,Heo JI,Kho YJ,Kang HJ,Park SH,Lee JY

更新日期：2012-01-01 00:00:00

abstract：:Bisphosphonates (BPs) inhibit bone resorption by preventing osteoclast maturation and apoptosis induction. Recently, BPs have also been shown to have antitumor effects against various types of carcinomas in vitro and in vivo. In this study, we investigated the antitumor effect of zoledronic acid (ZOL), a third generat...

journal_title：Oncology reports

authors： Tamura T,Shomori K,Nakabayashi M,Fujii N,Ryoke K,Ito H

更新日期：2011-04-01 00:00:00

abstract：:Oral mucositis is a severe complication of radiotherapy. Hence, it may constitute a serious medical safety risk for astronauts during extended space flights, such as missions to Mars, during which they are exposed to heavy-ion irradiation. For risk assessment of developing radiation-induced mucositis, a three-dimensio...

journal_title：Oncology reports

authors： Tschachojan V,Schroer H,Averbeck N,Mueller-Klieser W

更新日期：2014-11-01 00:00:00

abstract：:Zoledronic acid (Zometa, ZOL) is increasingly used to treat tumour-induced bone disease, and is also reported to have antiangiogenic properties in vivo. In this study, we have investigated the correlations between changes in the proangiogenic cytokine, vascular endothelial growth factor (VEGF), and markers of bone res...

journal_title：Oncology reports

authors： Santini D,Vincenzi B,Hannon RA,Brown JE,Dicuonzo G,Angeletti S,La Cesa A,Coleman RE,Tonini G,Budillon A,Caraglia M,Holen I

更新日期：2006-05-01 00:00:00

abstract：:The emergence of radioresistance is a significant issue in the treatment of squamous cell carcinoma. We recently demonstrated that post-radiogenic extracellular signal-regulated kinase (ERK) signaling might decrease radiosensitivity in this cancer type. To further elucidate how tumo...

journal_title：Oncology reports

authors： Affolter A,Schmidtmann I,Mann WJ,Brieger J

更新日期：2013-02-01 00:00:00

abstract：:Inhibitor of DNA-binding protein 1 (ID1) is commonly abnormally overexpressed in colorectal cancer (CRC); yet, the functional significance of ID1 in the growth and invasive properties of CRC cells remains largely unclear. The present study investigated the effects of ID1 downregulation on the cell growth and metastati...

journal_title：Oncology reports

authors： Lai X,Liao J,Lin W,Huang C,Li J,Lin J,Chen Q,Ye Y

更新日期：2014-07-01 00:00:00

abstract：:Low-intensity ultrasound (LIUS) combined with chemotherapy is an innovative modality for cancer treatment, but its effect on orthotopic carcinoma remains unknown. Our previous study revealed that LIUS enhanced the growth inhibitory effects of several chemotherapeutic drugs in nude mice with transplanted tumors. In the...

journal_title：Oncology reports

authors： Li HX,Zheng JH,Ji L,Liu GY,Lv YK,Yang D,Hu Z,Chen H,Zhang FM,Cao W

更新日期：2018-04-01 00:00:00

abstract：:MicroRNAs (miRNAs or miRs) contribute to the development of various malignant neoplasms, including glioblastoma multiforme (GBM). The present study aimed to explore the pathogenesis of GBM and to identify latent therapeutic agents for patients with GBM, based on an in silico analysis. Gene chips that provide miRNA exp...

journal_title：Oncology reports

authors： Xiong DD,Xu WQ,He RQ,Dang YW,Chen G,Luo DZ

更新日期：2019-04-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a ubiquitous pathogen that was first identified as a human cancer virus. Many human cancers are associated with EBV, and we demonstrated that EBV infects macrophages. Macrophages infected with EBV show a close correlation with many human cancers, and thus more attention must be given to the...

journal_title：Oncology reports

authors： Shimakage M

更新日期：2014-11-01 00:00:00

abstract：:Post‑transcriptional mechanisms are an important approach in the treatment of cancer, and may also be hijacked by tumor cells to help adapt to the local microenvironment. Filamin B (FLNB), an actin‑binding protein that provides crucial scaffolds for cell motility and signaling, has also been identified as an RNA‑bindi...

journal_title：Oncology reports

authors： Ma HR,Cao L,Wang F,Cheng C,Jiang R,Zhou H,Xie Z,Wuermanbieke S,Qian Z

更新日期：2020-05-01 00:00:00

abstract：:It has been reported that granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage-colony stimulating factor (GM-CSF) can mobilize endothelial progenitor cells (EPCs) in bone marrow cells (BMCs) into peripheral blood (PB) in vivo. Previously, we also reported that macrophage-colony stimulating factor (...

journal_title：Oncology reports

authors： Zhang Y,Adachi Y,Iwasaki M,Minamino K,Suzuki Y,Nakano K,Koike Y,Mukaide H,Shigematsu A,Kiriyama N,Li C,Ikehara S

更新日期：2006-06-01 00:00:00

abstract：:Sentinel lymph node (SLN) biopsy is a useful way of assessing axillary nodal status and obviates unnecessary axillary lymph node dissection for patients with node-negative breast cancer. However, SLN can also be located in the internal mammary lymph node (IMN) chain or elsewhere. The practicability and relevance of in...

journal_title：Oncology reports

authors： Noguchi M

更新日期：2002-05-01 00:00:00

abstract：:RNA‑binding motif 3 (RBM3) is a cold‑shock protein that has been previously shown to attenuate cancer stem cell‑like features in prostate cancer (PCa) cells. However, the mechanism underlying RBM3 regulation in PCa cells is largely unknown. The present study investigated the impact of RBM3 expression on the whole tran...

journal_title：Oncology reports

authors： Dong Q,Lv C,Zhang G,Yu Z,Kong C,Fu C,Zeng Y

更新日期：2018-10-01 00:00:00

abstract：:The purpose of this study was to define gene expression profile changes in colorectal tumors in order to identify target genes involved in neoplastic progression. cDNA microarray analysis was used to detect differences in gene expression profiles between colon tumor samples obtained from 20 patients in different tumor...

journal_title：Oncology reports

authors： Bandres E,Catalan V,Sola I,Honorato B,Cubedo E,Cordeu L,Andion E,Escalada A,Zarate R,Salgado E,Zabalegui N,García F,Garcia-Foncillas J

更新日期：2004-08-01 00:00:00

abstract：:Although radiotherapy is routinely administered to high-risk endometrial carcinoma and offer a significant disease-free survival advantage, the therapeutic effect is sometimes limited by the occurrence of radioresistance. To determine the patterns of gene expression responsible for the radioresistance and to search fo...

journal_title：Oncology reports

authors： Du XL,Jiang T,Wen ZQ,Li QS,Gao R,Wang F

更新日期：2009-03-01 00:00:00

abstract：:DNA damage sensor proteins are recognized as upstream components of the DNA damage checkpoint signaling pathway and are required for cell cycle control and the induction of apoptosis. hRad9 plays an important role as an upstream regulator of checkpoint signaling. In our previous studies, we confirmed the significant a...

journal_title：Oncology reports

authors： Yuki T,Maniwa Y,Doi T,Okada K,Nishio W,Hayashi Y,Okita Y

更新日期：2008-11-01 00:00:00

abstract：:ZNF703, a member of the NET/Nlz family of zinc finger transcription factors, contributes to aspects of developmental growth and patterning across evolutionarily diverse species. ZNF703 has been identified as a novel oncogene in human breast cancer. In the present study, we investigated the expression of ZNF703 in gast...

journal_title：Oncology reports

authors： Yang G,Ma F,Zhong M,Fang L,Peng Y,Xin X,Zhong J,Yuan F,Gu H,Zhu W,Zhang Y

更新日期：2014-04-01 00:00:00

abstract：:MicroRNA-374a (miR-374a) is involved in the progress of various types of cancer, and may indicate a poor prognosis. However, its role in esophageal cancer remains to be determined. In the present study, the role of miR-374a in esophageal cancers and cancer cell growth was examined using miR-374a overexpression and und...

journal_title：Oncology reports

authors： Wang Y,Xin H,Han Z,Sun H,Gao N,Yu H

更新日期：2015-10-01 00:00:00

abstract：:Cervical cancer is the second most common gynecological malignancy. The mechanisms of the genesis and progression of cervical cancer are complicated and not thoroughly understood. DEK is reported as an oncogene in various cancers, such as acute myeloid leukemia, bladder cancer, breast cancer and hepatocellular cancer....

journal_title：Oncology reports

authors： Xu X,Zou L,Yao Q,Zhang Y,Gan L,Tang L

更新日期：2017-08-01 00:00:00

abstract：:Adenoid cystic carcinoma (ACC) is a generally slow-growing but highly malignant salivary gland neoplasm with remarkable capacities for local invasion and lung metastasis. The precise characteristics of ACC are not fully understood because there was no suitable animal model. We have successfully established a new human...

journal_title：Oncology reports

authors： Hashitani S,Urade M,Zushi Y,Segawa E,Okui S,Sakurai K

更新日期：2007-01-01 00:00:00

abstract：:Mutations of the von Hippel-Lindau (VHL) tumor suppressor gene cause hereditary and sporadic renal cell carcinomas (RCCs). The best characterized function of VHL protein is suppression of the α subunit of hypoxia inducible factor (HIF). Additional VHL functions have been reported, including induction of senescence upo...

journal_title：Oncology reports

authors： Macher-Goeppinger S,Bermejo JL,Schirmacher P,Pahernik S,Hohenfellner M,Roth W

更新日期：2013-11-01 00:00:00

abstract：:Livistona chinensis seeds have been used for centuries to clinically treat various types of cancer. Our published data suggest that Livistona chinensis seeds are able to inhibit hepatocellular carcinoma (HCC) growth in vitro and in vivo via promotion of mitochondrial-dependent apoptosis. To further elucidate the molec...

journal_title：Oncology reports

authors： Lin W,Zhao J,Cao Z,Zhuang Q,Zheng L,Zeng J,Hong Z,Peng J

更新日期：2014-04-01 00:00:00

abstract：:The pre-S mutant LHBs, especially the pre-S2 type, is believed to be crucial in HBV-associated hepatocellular carcinogenesis. However, the mechanism of HBV-induced hepatocellular carcinoma is not fully understood. To identify the mechanism, pre-S2 LHBs-interacting proteins were stud...

journal_title：Oncology reports

authors： Lei Y,Liu H,Yang Y,Wang X,Ren N,Li B,Liu S,Cheng J,Fu X,Zhang J

更新日期：2012-01-01 00:00:00