Male reproductive health: cause for concern?

Abstract:

:A substantial body of evidence has accumulated in recent years that human semen quality may be deteriorating. This has been associated with evidence of other changes in male reproductive health, including increases in congenital malformations and testicular cancer in humans, and similar problems in wildlife. Unfortunately, the evidence remains inconclusive. It has been suggested that these changes may be due to environmental xeno-oestrogens acting during development. Although there is now a large quantity of data indicating that this is a plausible hypothesis, evidence of causality, rather than association, remains to be provided. The potential importance of these changes for human health is considerable and urgent research is required to clarify the situation.

journal_name

Andrologia

journal_title

Andrologia

authors

Irvine DS

doi

10.1046/j.1439-0272.2000.00388.x

keywords:

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

195-208

issue

4-5

eissn

0303-4569

issn

1439-0272

journal_volume

32

pub_type

杂志文章,评审
  • Dynamics of sperm DNA damage in fresh versus frozen-thawed and gradient processed ejaculates in human donors.

    abstract::The rate of increase of sperm DNA fragmentation (rsDF) in fresh and frozen-thawed and processed sperm samples after a density gradient for sperm selection was analysed after 0, 0.5, 1.5, 4.5, 6, 24, 48 and 72 h of incubation at 37 °C, in five donors with proven fertility. The results showed that: (i) sperm DNA fragmen...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2010.01022.x

    authors: Gosálvez J,Núñez R,Fernández JL,López-Fernández C,Caballero P

    更新日期:2011-12-01 00:00:00

  • Dimethylformamide is not better than glycerol for cryopreservation of boar semen.

    abstract::To improve the boar sperm cryopreservation process, the influence of the sugar (lactose, trehalose) source and the cryoprotectant [glycerol, dimethylformamide (DMF)] on the success of freezing was investigated. Sperm samples were frozen in one of six extenders: lactose plus 3% glycerol (LG); lactose plus 1.5% glycerol...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2011.01237.x

    authors: Malo C,Gil L,Cano R,Martínez F,García A,Jerez RA

    更新日期:2012-05-01 00:00:00

  • Dopamine D2 receptors in the basolateral amygdala modulate erectile function in a rat model of nonorganic erectile dysfunction.

    abstract::Nonorganic erectile dysfunction is a problem with unknown central mechanisms. Changes in brain activity in the amygdala have been observed in human patients. This study aimed to investigate the dopamine system in the basolateral amygdala of male rats with nonorganic erectile dysfunction. We applied chronic mild stress...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13160

    authors: Chen G,Chen J,Yang B,Yu W,Chen Y,Dai Y

    更新日期:2019-02-01 00:00:00

  • Effects of H(2)O(2) exposure on human sperm motility parameters, reactive oxygen species levels and nitric oxide levels.

    abstract::Research has revealed that reactive oxygen species (ROS) negatively affect sperm function, both in vivo and in vitro. Sperm preparation techniques for assisted reproductive technologies (ART) are potential causes for additional ROS production. This study aimed to correlate the concentration of exogenous H(2)O(2) with ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2009.00980.x

    authors: du Plessis SS,McAllister DA,Luu A,Savia J,Agarwal A,Lampiao F

    更新日期:2010-06-01 00:00:00

  • Nuclear sperm quality in total polymorphic teratozoospermia and its impact on intracytoplasmic sperm injection outcome.

    abstract::Various nuclear sperm alterations are reported in patients with syndromic teratozoospermia; however, this has not been clearly identified yet in total polymorphic teratozoospermia. The aim of this study was to analyse sperm aneuploidy, DNA integrity and chromatin packaging in 45 infertile patients with total polymorph...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13252

    authors: Braham A,Ghedir H,Zidi I,Sallem A,Hajlaoui A,Ajina M,Saad A,Ibala-Romdhane S

    更新日期:2019-06-01 00:00:00

  • Purification and properties of gamma-glutamyl transpeptidase from human testis.

    abstract::Gamma-glutamyl transpeptidase was purified to apparent homogeneity from human testis by DEAE cellulose, acetone, precipitation, fractionation by ammonium sulphate, Sephacryl S-200 chromatography, Q-Sepharose chromatography and S-Sepharose chromatography following solubilization of the enzyme by Triton X-100. The purif...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1990.tb01973.x

    authors: Yoshida K,Arai K,Kobayashi N,Saitoh H

    更新日期:1990-05-01 00:00:00

  • An immunohistochemical study for testicular biopsies in cases of male infertility.

    abstract::Immunohistochemical and morphological examination of 50 bilateral testicular biopsies of infertile men shows the presence of immunoglobulin in 20% of the cases, suggesting that testicular immune phenomena might be implicated in the pathogenesis of infertility. Several observations make it clear that immune phenomena a...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1980.tb00594.x

    authors: Jadot-Van De Casseye M,De Bled G,Gepts W,Schoysman R

    更新日期:1980-03-01 00:00:00

  • The kinetic of acrosome reaction--an additional sperm parameter?

    abstract::Spermatozoa of six men with normozoospermia, oligozoospermia and teratozoospermia were capacitated in vitro in modified Tyrode's medium und evaluated for acrosome reaction using the recently described triple-stain technique. The resulting kinetics illustrate the different capacitation behaviour and ability of spermato...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1985.tb00991.x

    authors: Töpfer-Petersen E,Heissler E,Schill WB

    更新日期:1985-05-01 00:00:00

  • Separation of sub-populations of sperm with higher fertility potential from normal and pathological semen by peanut agglutinin.

    abstract::Incubation of human sperm from semen with counts below 20 x 10(6)/ml with peanut agglutinin (PNA) resulted in agglutination of about 70% of sperm. An inverse correlation was found between non-agglutinating (PNA) sperm and sperm density (r = 0.48, p less than 0.01) and a direct correlation with acrosome-damaged sperm (...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1990.tb01970.x

    authors: Ravid A,Sagiv M,Bartoov B,Eltes F,Novogrodsky A,Allalouf D,Levinsky H,Singer R

    更新日期:1990-05-01 00:00:00

  • The effect of alpha-difluromethylornithine and tartaric acid on sperm count, seminal gamma GT, FSH, LH, testosterone and steroid excretion in patients with chronic prostatitis.

    abstract::The inactivation of ornithine decarboxylase, a polyamine biosynthetic enzyme, by alpha-difluoromethylornithine (alpha-DFMO) was studied in patients with chronic non-suppurative prostatitis. Partial clinical response and remission of gross hematospermia were observed after 18 g/day alpha-DFMO, when administered orally ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1981.tb00014.x

    authors: Dunzendorfer U,Feller H

    更新日期:1981-03-01 00:00:00

  • Enzyme levels in semen of men with different types of azoospermia.

    abstract::The levels of eight enzymes have been measured in the semen of 15 azoospermic subjects. The results indicate that the values of the enzymes Creatine kinase, and Alanine aminotransferase, just as the Aspartate aminotransferase/Alanine aminotransferase ratio are significantly different between excretory and secretory az...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1982.tb03099.x

    authors: Gonzalez Buitrago JM,Garcia Diez LC

    更新日期:1982-01-01 00:00:00

  • [Significance of linear cervix mucus penetration for the evaluation of spermatozoa quality].

    abstract::Linear mucus penetration of spermatozoa from 75 arbitrary selected men was evaluated using a non-commercial bovine cervix mucus preparation in the same way as Penetrak, but using round glass capillary tubes instead of flat plastic tubes. The mean penetration value was 28.7 +/- 7.10 mm in 90 min and the mean sperm dens...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Engel S,Schachschal G,Petzoldt R

    更新日期:1990-07-01 00:00:00

  • Acute bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome: andrological implications.

    abstract::There is a consensus on the diagnostic management of bacterial prostatitis (acute and chronic). In chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) the diagnostic approach remains unclear, because inflammatory and noninflammatory CP/CPPS might be one entity with varying findings over time. The WHO definition...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0272.2007.00828.x

    authors: Weidner W,Wagenlehner FM,Marconi M,Pilatz A,Pantke KH,Diemer T

    更新日期:2008-04-01 00:00:00

  • Metabolic evaluation of cooled equine spermatozoa.

    abstract::Microscopy has been used in the routine evaluation of sperm metabolism. Nevertheless, it has limited capacity to preview male fertility. As calorimetry may be used to evaluate directly the metabolic activity of a biological system, the aim of this study was to use microcalorimetry as an additive method for sperm metab...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2009.00963.x

    authors: Vasconcelos AB,Santana MA,Santos AM,Santoro MM,Lagares MA

    更新日期:2010-04-01 00:00:00

  • Effects of hydrogen sulphide donor, sodium hydrosulphide treatment on the erectile dysfunction in L-NAME-induced hypertensive rats.

    abstract::Men with hypertension often develop erectile dysfunction (ED). The present study aimed to examine the effects of sodium hydrosulphide (NaHS), a hydrogen (H2 S) donor, treatment on ED in nitric oxide synthase (NOS) inhibitor (L-NAME)-induced hypertensive rats. Forty adult Sprague-Dawley rats were divided into four grou...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13240

    authors: Yilmaz E,Kaya-Sezginer E,Yilmaz-Oral D,Cengiz T,Bayatli N,Gur S

    更新日期:2019-06-01 00:00:00

  • Effect of lycopene on testicular androgenic and anti-oxidative enzymes in cyproterone acetate-induced male infertile Wistar strain albino rats: An in vitro study.

    abstract::Incidents of male infertility are mushrooming worldwide. Oxidative stress plays a prime role for its onset. Considering this background, the study was designed to focus the direct role of lycopene on cyproterone acetate (CPA) induced testicular hypofunction in rat. Four groups have been considered including the vehicl...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13494

    authors: Tripathy A,Ara F,Ghosh P,Ghosh D

    更新日期:2020-04-01 00:00:00

  • Microcinematographic analysis of the motility of human spermatozoa incubated with caffeine.

    abstract::The effects of incubation with caffeine at final concentration of 0.5 and 5.0 mM for 30 min at ambient temperature were examined in three normal semen samples and three from asthenozoospermic men. A 50 frames/s microcinematographic analysis of the sperm motility was performed and two characteristic parameters of the t...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1982.tb02295.x

    authors: Serres C,Feneux D,David G

    更新日期:1982-09-01 00:00:00

  • The value of epididymal protease inhibitor in differential diagnosis between obstructive azoospermia and non-obstructive azoospermia.

    abstract::There are no efficient and noninvasive clinical tests to distinguish between obstructive azoospermia (OA) and non-obstructive azoospermia (NOA). Epididymal protease inhibitor (Eppin) protein is secreted specifically by testes and epididymides in male reproductive system. It does not exist in seminal plasma of patients...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2011.01085.x

    authors: Liu B,Su S,Wang P,Niu X,Yang X,Zhang W,Wang Z,Wang X

    更新日期:2011-10-01 00:00:00

  • The effects of bacterial infection on human sperm nuclear protamine P1/P2 ratio and DNA integrity.

    abstract::The purpose of this study was to detect the effects of bacterial infection on human sperm nuclear protamines and DNA fragmentation. In this study, 120 semen samples were collected from unselected male partners of couples consulting for infertility in infertility and obstetrics clinic. All the samples were screened bac...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12841

    authors: Zeyad A,Hamad MF,Hammadeh ME

    更新日期:2018-03-01 00:00:00

  • Chlorinated pesticide residues in testicular tissue samples. Pesticides in human testicles.

    abstract::Residues of chlorinated pesticides--HCB, alpha-, beta-, gamma-, delta-, epsilon-HCH isomers, heptachlor epoxide, DDE and DDT isomers in bilateral testicular biopsy material were determined in gas liquid chromatography with electron capture detector (GLC-ECD). The average levels of chlorinated pesticides residues occur...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1983.tb00196.x

    authors: Szymczynski GA,Waliszewski SM

    更新日期:1983-11-01 00:00:00

  • Germ cell apoptosis induced by experimental cryptorchidism is mediated by molecular pathways in mouse testis.

    abstract::The aim of the study was to characterise the alterations in expression of some apoptosis regulators in unilaterally and bilaterally heat-treated mouse testes at different time intervals to 42 days after surgery. Cryptorchidism was induced in immature mice by returning the testis to the abdominal cavity via a surgical ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2009.00947.x

    authors: Absalan F,Movahedin M,Mowla SJ

    更新日期:2010-02-01 00:00:00

  • A quantitative morphological study of age-related changes in the donkey testis in the period between puberty and senium.

    abstract::The testis of the donkey was used as a model to study age-related changes in the period between puberty and senium. From the age of 1.5 years to the middle of sexual maturity (5 to 6 years) a number of histophysiological features, all indicative of the spermatogenetic efficiency, increase continuously. Then without a ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1997.tb00310.x

    authors: Nipken C,Wrobel KH

    更新日期:1997-05-01 00:00:00

  • Sperm DNA methylation of H19 imprinted gene and male infertility.

    abstract::Infertility affects up to 15% of reproductive-aged couples worldwide, with male factor being detected in 40%-50% of the cases. Proper sperm production is associated with the establishment of appropriate epigenetic marks in developing germ cells. Several studies have demonstrated the association between abnormal sperma...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12766

    authors: Nasri F,Gharesi-Fard B,Namavar Jahromi B,Farazi-Fard MA,Banaei M,Davari M,Ebrahimi S,Anvar Z

    更新日期:2017-12-01 00:00:00

  • Prevalence of carcinoma in situ in testicular biopsies of infertile Iranian men.

    abstract::Almost all testicular germ cell tumours are proved to originate from carcinoma in situ cells. Infertility is one of the factors that increase the risk of carcinoma in situ. The reported prevalence for carcinoma in situ from different parts of the world is 0-3.7% in infertile men. This retrospective study was performed...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12139

    authors: Soltanghoraee H,Pourkeramati F,Khoddami M,Amirjannati N,Akhondi MM,Soltani A

    更新日期:2014-09-01 00:00:00

  • Changes in sexual performance and biochemical characterisation of functional neural regions: A study in serotonin transporter knockout male rats.

    abstract::To explore the correlation between SERT expression and sexual activities and seek the possible mechanism of SERT in regulating ejaculations, we analysed the sexual activities and biochemical characteristics of five measured neural regions in three rat genotypes (SERT-/- , SERT+/- and SERT+/+ ). The results showed the ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13291

    authors: Geng H,Peng D,Huang Y,Tang D,Gao J,Zhang Y,Zhang X

    更新日期:2019-08-01 00:00:00

  • Evaluation of human sperm membrane integrity using the water test and the hypoosmotic test.

    abstract::The objective of the study was to compare the water test and the hypoosmotic test (HOS) in the assessment of the human sperm membrane. A total of 686 semen samples from human male donors were subjected to water and HOS tests after routine semen evaluation. The mean percentage of swollen spermatozoa was 71.8 +/- 9.6% i...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1046/j.1439-0272.2001.00374.x

    authors: Bahamondes L,Fazano F,De Lucio MA,Neves PA,Bottcher Luiz F,Lorenzetti GB

    更新日期:2001-03-01 00:00:00

  • Protective effect of thymoquinone against testicular torsion induced oxidative injury.

    abstract::We aimed to determine the protective effects of thymoquinone (TQ), against ischaemia-reperfusion (I/R) injury in the testis tissue of rats. Twenty-seven male Wistar albino rats were randomly divided into three equal groups as follows: Group I, sham group; Group II, torsion group; and Group III, torsion + thymoquinone ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12424

    authors: Ayan M,Tas U,Sogut E,Caylı S,Kaya H,Esen M,Erdemir F,Uysal M

    更新日期:2016-03-01 00:00:00

  • Sperm selection strategies and their impact on assisted reproductive technology outcomes.

    abstract::The application of assisted reproductive technologies (ART) has revolutionised the treatment of human infertility, giving hope to the patients previously considered incapable of establishing pregnancy. While semen analysis is performed to access whether a sample has an adequate number of viable, motile and morphologic...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.13725

    authors: Pinto S,Carrageta DF,Alves MG,Rocha A,Agarwal A,Barros A,Oliveira PF

    更新日期:2020-06-28 00:00:00

  • Therapeutic options in male genital tract inflammation.

    abstract::Chronic inflammatory conditions of the genital tract are still unsatisfactorily recognised in the workup of male infertility due to inappropriate definitions and inconsistent diagnostic criteria. The most popular term used for description of both, infections and inflammation in the genital tract is MAGI (male accessor...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.13207

    authors: Haidl G,Haidl F,Allam JP,Schuppe HC

    更新日期:2019-04-01 00:00:00

  • Abutilon pannosum stem bark enhances the aphrodisiac activities and spermatogenesis in rat.

    abstract::Abutilon pannosum (Forst.f.) Schlecht. is used for male sexual performance. In this study, we have investigated aphrodisiac potential of A. pannosum stem bark methanol extract (APM) in rat. Male rats were administered with APM (400 mg/kg) on daily basis for 5, 10 and 15 days. Time interval for mount latency, intromiss...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13404

    authors: Khalil I,Khan MR,Ghani M,Akbar F

    更新日期:2019-11-01 00:00:00