Abstract:
:A cognitive task can often be subdivided into several subprocesses, which follow a specific temporal order. Here, we report an event-related functional magnetic resonance imaging (fMRI) experiment on memory search, in which the temporal onset of search in primary memory was varied relative to retrieval from secondary memory. Furthermore, previous behavioral studies demonstrated that search times in primary memory depend on the number of items in a memory set, whereas retrieval from secondary memory is a set-size independent process. We analyzed the dependency of the blood oxygenation level dependent (BOLD)-response on the temporal onset of memory search on the one hand and on memory set size on the other hand to differentiate the contribution of retrieval from secondary memory, maintenance in primary memory, item search in primary memory, and response-related processes. The timing of activation followed cue presentation bilaterally in the middle frontal gyri (Brodmann area (BA) 9,46) and the inferior parts of the precentral gyri (BA6). In all other regions of interest (ROI), supplementary motor area (SMA), posterior parietal cortex, antero-superior insula, and primary motor cortex, the onset of activation was delayed with delayed probe presentation, ruling out participation in retrieval from secondary memory. The amplitude of the BOLD-response increased with increasing memory set size in all ROI except primary motor cortex and left posterior parietal cortex. All areas with cue-associated BOLD onset, suggesting involvement in retrieval, showed prolonged BOLD activation, suggesting that they also support maintenance of the retrieved information.
journal_name
Microsc Res Techjournal_title
Microscopy research and techniqueauthors
Pollmann S,Zysset S,Wiggins CJ,Von Cramon DYdoi
10.1002/1097-0029(20001001)51:1<29::AID-JEMT3>3.0.keywords:
subject
Has Abstractpub_date
2000-10-01 00:00:00pages
29-38issue
1eissn
1059-910Xissn
1097-0029pii
10.1002/1097-0029(20001001)51:1<29::AID-JEMT3>3.0.journal_volume
51pub_type
杂志文章abstract::Microscopic imaging of uneven surfaces is difficult because of the limited depth of field. In this study, we developed a rapid auto-focus method for uneven surfaces based on image fusion. The Prewitt operator was used to detect the vertical edges of the images. Then, the focus position was theoretically calculated usi...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23328
更新日期:2019-09-01 00:00:00
abstract::The discovery of new song types in Hawaiian Drosophila species has raised a question of alternative sound production and sound perception mechanisms in Drosophila. For example D. disjuncta males, which produce song with a carrier frequency of 5,000-6,000 Hz, do not vibrate their wings but only tremble them in a very s...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/1097-0029(20000715)50:2<161::AID-JEMT8>3.0
更新日期:2000-07-15 00:00:00
abstract::Surface ultrastructures of gill filaments and secondary lamellae of Rita rita and Cirrhinus mrigala, inhabiting different ecological habitat, were investigated to unravel adaptive modifications. R. rita is a sluggish, bottom dwelling carnivorous catfish, which inhabits regions of river with accumulations of dirty wate...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.21074
更新日期:2012-04-01 00:00:00
abstract::Classical conditioning (CC) with a sweet flavored is useful for experimental models of immune response. The objective this work was analyze spleen cell response on the differentiation of B-lymphocytes associated with the CC with sweet flavored in adult rats. Twelve adult male rats were divided (n = 3) in Group 1 (cont...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23112
更新日期:2018-12-01 00:00:00
abstract::Despite the large number of species, their wide distribution, and unique reproductive characteristics, Neotropical bats have been poorly studied, and important aspects of the reproduction of these animals have not been elucidated. We made an ultrastructural analysis of spermatogenesis in Molossus molossus (Molossidae)...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22005
更新日期:2012-07-01 00:00:00
abstract::Haematoxylin/Eosin staining was performed to screen for Hirano bodies from the temporal lobe including the hippocampus in 10 Pick's disease cases containing Pick bodies. Although the inclusions were confirmed in 9 out of 10 cases, only 4 out of 10 were particularly enriched with the eosinophilic bodies. These were sub...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22206
更新日期:2013-06-01 00:00:00
abstract::Nowadays the processes of crossing of different mammalian species are well characterized in light of genetics, and possibility of reproduction. Generally, lack detailed studies on changes in anatomy and histology of internal systems of hybrids. Bison bonasus hybrid is an interspecific species between the bull of Europ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23516
更新日期:2020-10-01 00:00:00
abstract::Golgi impregnations reveal a variety of dendritic morphologies amongst Kenyon cells in the mushroom bodies of Drosophila melanogaster. Different morphological types of Kenyon cells contribute axon-like processes to five divisions of the medial and vertical lobes. Four of these divisions have characteristic affinities ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.10368
更新日期:2003-10-01 00:00:00
abstract::Automated detection and classification of gastric infections (i.e., ulcer, polyp, esophagitis, and bleeding) through wireless capsule endoscopy (WCE) is still a key challenge. Doctors can identify these endoscopic diseases by using the computer-aided diagnostic (CAD) systems. In this article, a new fully automated sys...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23447
更新日期:2020-05-01 00:00:00
abstract::The aim of this study is to evaluate the antitumor effect of indirubin-3-monoxime and its mode of action in benzo(α)pyrene [B(α)P] induced lung cancer in A/J mice. Light microscopic examination of lung sections of [B(α)P] induced lung cancer mice revealed the presence of adenocarcinoma characterized by extensive proli...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20832
更新日期:2010-10-01 00:00:00
abstract::Biodegradable microspheres such as those made of poly-D,L-lactide (PDLLA) are widely investigated delivery systems for drugs or antigens. The aim of this study was to examine experimental conditions in order to produce PDLLA microspheres with the best properties for controlled and sustained drug delivery by the modifi...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20529
更新日期:2008-02-01 00:00:00
abstract::The dynamic transmission electron microscope (DTEM) is introduced as a novel tool for in situ processing of materials. Examples of various types of dynamic studies outline the advantages and differences of laser-based heating in the DTEM in comparison to conventional (resistive) heating in situ TEM methods. We demonst...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20664
更新日期:2009-03-01 00:00:00
abstract::Term and preterm cervical ripening and dilatation have similarities with an inflammatory reaction. Since cell adhesion molecules are involved in this process, investigations on the expression of intercellular adhesion molecule-1, endothelial leukocyte adhesion molecule-1, vascular cell adhesion molecule-1, and platele...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.10281
更新日期:2003-03-01 00:00:00
abstract::Several studies searching for methods to control Rhipicephalus sanguineus s.l., (dog tick) infestations have been developed aiming to minimize the damages caused by these ectoparasites to the hosts and the environment, which is harmed by the indiscriminate use of toxic acaricide products. In this scenario, neem oil ha...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.22871
更新日期:2017-08-01 00:00:00
abstract::Focused ion beam (FIB) techniques are among the most important tools for the nanostructuring of surfaces. We used the FIB/SEM (scanning electron microscope) for milling and imaging of digestive gland cells. The aim of our study was to document the interactions of FIB with the surface of the biological sample during FI...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20494
更新日期:2007-10-01 00:00:00
abstract::Widespread implementation of prostate cancer screening has affected several epidemiologic features of the disease including incidence, tumor and patient characteristics, patterns of care and outcomes. Some of these changes have been interpreted as evidence of the success of PSA testing as a cancer control strategy. Da...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/1097-0029(20001201)51:5<415::AID-JEMT2>3.0
更新日期:2000-12-01 00:00:00
abstract::This work provides examples of some of the imaging capabilities of environmental scanning electron microscopy applied to easily charged samples relevant to particle analysis. Environmental SEM (also referred to as high pressure or low vacuum SEM) can address uncoated samples that are known to be difficult to image. Mo...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1070250507
更新日期:1993-08-01 00:00:00
abstract::The aqueous extract of betel nut (AEBN) induces the formation of preneoplastic nodules in the liver of Swiss Albino mice and leads to increased predisposition to cancer when administered transgenerationally. The aim of this investigation was to elucidate the alterations in ultrastructure of subcellular organelles in t...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20791
更新日期:2010-05-01 00:00:00
abstract::This paper presents electron-microscopic observations on biopsies of the olfactory mucosae of several classes of patients with smell disorders: 1) patients with loss of smell function following head injury (post-traumatic anosmics or hyposmics); 2) patients with loss of smell function following severe head colds and/o...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.1070230202
更新日期:1992-10-15 00:00:00
abstract::Cigarette smoke is a significant source of cadmium, lead, and toxic elements, which are absorbed into the human organism. In this context, the aim of this study was to investigate in vitro the presence of toxic elements, cadmium, and lead deriving from cigarette smoke in the resin composite, dentine, and dental enamel...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20903
更新日期:2011-03-01 00:00:00
abstract::We discuss the use of fluorescence correlation spectroscopy for the measurement of relatively slow rotations of large macromolecules in solution or attached to other macromolecular structures. We present simulations and experimental results to illustrate the range of rotational correlation times and diffusion times th...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20121
更新日期:2004-11-01 00:00:00
abstract::Anatomical study of leaf xylary vessel elements of Carthamus oxycantha under various intensities of lead (Pb) and nickel (Ni) stress (200, 400, 600, and 800 mg Pb(NO3 )2 , NiCl2 ·6H2 O/kg of the soil) was conducted. The deformations caused due to metal stress were detected using point-based image registration techniqu...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23476
更新日期:2020-07-01 00:00:00
abstract::Among the five senses, the sense of smell (olfaction) is the most sensitive and emotional window on the outside world (Stern and Marx, 1999). The olfactory system recognizes and discriminates myriad odorants of diverse molecular structures. What makes the olfactory system so specific and sensitive? OE harboring the ol...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.10130
更新日期:2002-08-01 00:00:00
abstract::From the first cases of bovine spongiform encephalopathy (BSE) among cattle in the United Kingdom in 1986, the route of infection of BSE is generally believed by means of feeds containing low level of processed animal proteins (PAPs). Therefore, many feed bans and alternative and complementary techniques were resulted...
journal_title:Microscopy research and technique
pub_type: 杂志文章,评审
doi:10.1002/jemt.20951
更新日期:2011-08-01 00:00:00
abstract::On continuing our studies on head and neck neoplasia, specimens from salivary gland tumors have been explored by using infrared microimaging spectroscopy to discern healthy from neoplastic tissues. Samples with Warthin tumor, epithelial displasia, marginal B-cell lymphoma, low-grade adenocarcinoma, and adenoid cystic ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20644
更新日期:2009-02-01 00:00:00
abstract::The mammary adenocarcinoma cell line MTLn3 is chemotactic towards epidermal growth factor (EGF), and this induced motility is thought to promote breast cancer invasion and metastasis. Stimulation of MTLn3 cells with EGF results in the extension of a flat, thin structure filled with filamentous actin and termed a lamel...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0029(19981201)43:5<433::AID-JEM
更新日期:1998-12-01 00:00:00
abstract::The rapid photothermal lysis of Escherichia coli O157:H7 treated with light-triggered Janus nanomotors was visualized by Hilbert differential contrast transmission electron microscopy (HDC-TEM). The extraordinary advantage of this high-resolution microscopic technique was that it revealed the detailed ultrastructure a...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.23657
更新日期:2020-11-27 00:00:00
abstract::This report describes osteoclastic bone resorption around intraosseous fixation screws in rat and pig mandibles. These screws supported distraction devices and provided for neutral fixation following the distraction period. Progressive clinical instability of bicortical screws and radiographic and histologic evidence ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.10376
更新日期:2003-08-15 00:00:00
abstract::The through focus exit wave reconstruction technique uses a series of high resolution electron microscopy images to reconstruct the complex electron wavefunction at the exit plane of the specimen. The feasibility of the through focus exit wave reconstruction method and its most important limitations are discussed. It ...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0029(20000501)49:3<301::AID-JEM
更新日期:2000-05-01 00:00:00
abstract::Fluorescence correlation spectroscopy (FCS) has become an increasingly important measurement tool for biological and biomedical investigations, with the capability to assay molecular dynamics and interactions both in vitro and within living cells. Information recovery in FCS requires an accurate characterization and c...
journal_title:Microscopy research and technique
pub_type: 杂志文章
doi:10.1002/jemt.20454
更新日期:2007-08-01 00:00:00