Molecular weight and antitumour activity of Zymomonas mobilis levans.

Abstract:

:Levans produced by several Zymomonas mobilis strains were classified by their viscosity average molecular weight and tested against sarcoma 180. Measurements of the samples' polydispersity were carried out to characterise the molecular weight distribution. The antitumour activities of levan samples were plotted against the viscosity average molecular weight and a maximum value of this activity was found at Mv = 210,000 (Mw = 456,900 and PD = 16.2). The results indicate that levan antitumour activities depend on the polysaccharide molecular weight and that a specific class of molecular weight may be responsible for this effect.

journal_name

Int J Biol Macromol

authors

Calazans GMT,Lima RC,de França FP,Lopes CE

doi

10.1016/s0141-8130(00)00125-2

keywords:

subject

Has Abstract

pub_date

2000-07-12 00:00:00

pages

245-7

issue

4

eissn

0141-8130

issn

1879-0003

pii

S0141813000001252

journal_volume

27

pub_type

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