Abstract:
:Centrosome reduction during spermiogenesis has been studied using anti-gamma-tubulin and anti-centrin antibodies and electron microscopy in nonhuman primates. Rhesus spermatids possess apparently normal centrosomes comprising a pair of centrioles associated with gamma-tubulin and centrin. However, they do not nucleate detectable microtubules. The spermatids discard gamma-tubulin in the residual bodies during the spermiation stage. Mature sperm do not have any detectable gamma-tubulin. About half of the centrin associated with the distal centriole degenerates during spermiogenesis and the remainder is intimately bound to the centriolar microtubules. The mature sperm possess highly degenerated distal centrioles. The centriolar microtubules degenerate in the rostral region and the ventral side of the sperm. The study indicates that the centrosome is reduced during rhesus spermiogenesis, but not completely as in mice.
journal_name
Mol Reprod Devjournal_title
Molecular reproduction and developmentauthors
Manandhar G,Schatten Gdoi
10.1002/1098-2795(200008)56:4<502::AID-MRD8>3.0.COkeywords:
subject
Has Abstractpub_date
2000-08-01 00:00:00pages
502-11issue
4eissn
1040-452Xissn
1098-2795pii
10.1002/1098-2795(200008)56:4<502::AID-MRD8>3.0.COjournal_volume
56pub_type
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更新日期:2012-09-01 00:00:00
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pub_type: 杂志文章,评审
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