Background illumination effects upon in vitro conditioning in Hermissenda.

Abstract:

:In the marine snail Hermissenda, associative learning can be accomplished by paired presentations of light and vestibular stimulation. It is generally assumed that associative learning depends upon the intensity or salience of the conditioned or unconditioned stimulus (CS and US, respectively). Accordingly, during Hermissenda conditioning a stronger dark adaptation is expected to render the CS (the light) more salient and hence facilitate association. We studied the influence of background illumination level using an in vitro pairing procedure in Hermissenda. This procedure allows one to assess the effect of conditioning upon a single cell, the B photoreceptor, which is implicated in this learning process. After 15 min of adaptation to a dim background light, B photoreceptors maintained a basal rate of firing, while after adaptation to complete darkness, they stopped firing. Paired and unpaired groups received 10 training trials in either a completely dark or a dim light environment. Although a trial to trial cumulative increase in excitability was found in the paired group trained in darkness, only the paired group trained under dim background light showed a higher input resistance and cell excitability 10 min after training. These results suggest that the background dim illumination was not needed for the induction but played a role in the maintenance of the pairing effect. Possible mechanisms for such a modulatory effect are discussed.

journal_name

Neurobiol Learn Mem

authors

Tomsic D,Alkon DL

doi

10.1006/nlme.1999.3938

keywords:

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

56-64

issue

1

eissn

1074-7427

issn

1095-9564

pii

S1074-7427(99)93938-2

journal_volume

74

pub_type

杂志文章
  • Long-term continuous, but not daily, environmental enrichment reduces spatial memory decline in aged male mice.

    abstract::Although environmental enrichment improves spatial memory and alters synaptic plasticity in aged rodents, it is unclear whether all types of enrichment treatments yield similar benefits. The present study examined the effects in aged male mice of three types of enrichment on spatial memory in Morris water maze and rad...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2005.09.003

    authors: Bennett JC,McRae PA,Levy LJ,Frick KM

    更新日期:2006-03-01 00:00:00

  • Transgenic inhibition of neuronal calcineurin activity in the forebrain facilitates fear conditioning, but inhibits the extinction of contextual fear memories.

    abstract::It is unclear whether protein phosphatases, which counteract the actions of protein kinases, play a beneficial role in the formation and extinction of previously acquired fear memories. In this study, we investigated the role of the calcium/calmodulin dependent phosphatase 2B, also known as calcineurin (CaN) in the fo...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2007.08.003

    authors: Havekes R,Nijholt IM,Visser AK,Eisel UL,Van der Zee EA

    更新日期:2008-05-01 00:00:00

  • Latent inhibition in conditioned taste aversion: the roles of stimulus frequency and duration and the amount of fluid ingested during preexposure.

    abstract::Two experiments examined the effects of total stimulus preexposure on latent inhibition (LI) in a conditioned taste aversion procedure with rats. Experiment 1 varied the frequency and duration of saccharin preexposures. LI was an increasing function of the product of frequency x duration. Experiment 2 kept saccharin e...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.1995.1051

    authors: De la Casa G,Lubow RE

    更新日期:1995-09-01 00:00:00

  • Post-encoding frontal theta activity predicts incidental memory in the reward context.

    abstract::Memories for daily events require that individuals integrate initial fragile traces of events over time. Recent evidence suggests that reward anticipation enhances memory performance and amplifies frontal theta activity for remembered items vs. forgotten items. However, little is known about how incidental rewards aft...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2019.01.008

    authors: Pu M,Yu R

    更新日期:2019-02-01 00:00:00

  • Parallel processing across neural systems: implications for a multiple memory system hypothesis.

    abstract::A common conceptualization of the organization of memory systems in brain is that different types of memory are mediated by distinct neural systems. Strong support for this view comes from studies that show double (or triple) dissociations between spatial, response, and emotional memories following selective lesions o...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章,评审

    doi:10.1016/j.nlm.2004.07.007

    authors: Mizumori SJ,Yeshenko O,Gill KM,Davis DM

    更新日期:2004-11-01 00:00:00

  • An application of Pavlovian principles to the problems of obesity and cognitive decline.

    abstract::An enormous amount of research has been aimed at identifying biological and environmental factors that are contributing to the current global obesity pandemic. The present paper reviews recent findings which suggest that obesity is attributable, at least in part, to a disruption of the Pavlovian control of energy regu...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章,评审

    doi:10.1016/j.nlm.2013.07.014

    authors: Davidson TL,Sample CH,Swithers SE

    更新日期:2014-02-01 00:00:00

  • The critical role of cholinergic basal forebrain neurons in morphological change and memory encoding: a hypothesis.

    abstract::It has been known for a long time that cholinergic basal forebrain neurons which project to the cerebral cortex play a role in learning and memory. Behavioral studies following lesions, for example, repeatedly have suggested multiple learning-related roles for these neurons. Apart from behavioral studies, cholinergic ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.1996.0068

    authors: Woolf NJ

    更新日期:1996-11-01 00:00:00

  • Chronic high-frequency repetitive transcranial magnetic stimulation improves age-related cognitive impairment in parallel with alterations in neuronal excitability and the voltage-dependent Ca2+ current in female mice.

    abstract::Chronic high-frequency repetitive transcranial magnetic stimulation (rTMS) is a noninvasive method to increase the excitability of neurons, and it induces long-term effects that can improve symptoms related to neurodegenerative diseases, including cognitive ability. The present study was undertaken to identify the mec...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2014.11.002

    authors: Wang HL,Xian XH,Wang YY,Geng Y,Han B,Wang MW,Li WB

    更新日期:2015-02-01 00:00:00

  • The neural basis of individual differences in memory performance in young and older adults: Using the encoding/retrieval flip account as framework.

    abstract::Aging is associated with cognitive decline, specifically in episodic memory. However, there are large individual differences in the extent of this decline and previous research suggests that these are associated with differences in executive functioning (EF). These EF differences, and associated differences in the enc...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2020.107251

    authors: Fu L,Maes JHR,Kessels RPC,Huijbers W

    更新日期:2020-09-01 00:00:00

  • Posterior insular cortex is necessary for conditioned inhibition of fear.

    abstract::Veridical detection of safety versus danger is critical to survival. Learned signals for safety inhibit fear, and so when presented, reduce fear responses produced by danger signals. This phenomenon is termed conditioned inhibition of fear. Here, we report that CS+/CS- fear discrimination conditioning over 5 days in r...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2016.08.004

    authors: Foilb AR,Flyer-Adams JG,Maier SF,Christianson JP

    更新日期:2016-10-01 00:00:00

  • Diversity of mnemonic function within the entorhinal cortex: a meta-analysis of rodent behavioral studies.

    abstract::The entorhinal cortex (EC) has been shown to be an integral piece of the hippocampal memory system. It sits in a unique position within the brain with strong, intricate, reciprocal connectivity with the hippocampus as well as a vast array of neocortical regions. Topographical patterns of afferent and efferent projecti...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.nlm.2014.08.006

    authors: Morrissey MD,Takehara-Nishiuchi K

    更新日期:2014-11-01 00:00:00

  • Involvement of the sigma receptor in passive-avoidance learning in the day-old chick during the second wave of neuronal activity.

    abstract::The specific sigma-receptor agonist (+)-SKF 10047 and antagonist BD 1047 were used to investigate whether this receptor was involved in passive-avoidance training in the day-old chick. We found 300 microM (+)-SKF 10047 to be amnesic when injected into the lobus parolfactorius 5 h after training (p < .01). Higher or lo...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.2000.3985

    authors: Freeman FM,Young IG

    更新日期:2001-05-01 00:00:00

  • Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome.

    abstract::Spatial working memory and the ability of a cholinesterase inhibitor to enhance memory were assessed at 4, 10, and 16 months of ages in control and Ts65Dn mice, a partial trisomy model of Down syndrome, with possibly significant relationships to Alzheimer's disease as well. In addition, ACh release during memory testi...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2007.05.007

    authors: Chang Q,Gold PE

    更新日期:2008-02-01 00:00:00

  • Both electrolytic and excitotoxic lesions of nucleus accumbens disrupt latent inhibition of learning in rats.

    abstract::Evidence indicating a role for the nucleus accumbens in the development of latent inhibition of learning has accumulated. Two experiments were conducted using Wistar rats to investigate this role directly. Experiment 1 used a conditioned emotional response paradigm to assess the effects of discrete electrolytic lesion...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.1995.1042

    authors: Tai CT,Cassaday HJ,Feldon J,Rawlins JN

    更新日期:1995-07-01 00:00:00

  • Metaplasticity within the spinal cord: Evidence brain-derived neurotrophic factor (BDNF), tumor necrosis factor (TNF), and alterations in GABA function (ionic plasticity) modulate pain and the capacity to learn.

    abstract::Evidence is reviewed that behavioral training and neural injury can engage metaplastic processes that regulate adaptive potential. This issue is explored within a model system that examines how training affects the capacity to learn within the lower (lumbosacral) spinal cord. Response-contingent (controllable) stimula...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2018.04.007

    authors: Grau JW,Huang YJ

    更新日期:2018-10-01 00:00:00

  • Conditional knockout of MET receptor tyrosine kinase in cortical excitatory neurons leads to enhanced learning and memory in young adult mice but early cognitive decline in older adult mice.

    abstract::Human genetic studies established MET gene as a risk factor for autism spectrum disorders. We have previously shown that signaling mediated by MET receptor tyrosine kinase, expressed in early postnatal developing forebrain circuits, controls glutamatergic neuron morphological development, synapse maturation, and corti...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2021.107397

    authors: Xia B,Wei J,Ma X,Nehme A,Liong K,Cui Y,Chen C,Gallitano A,Ferguson D,Qiu S

    更新日期:2021-01-29 00:00:00

  • Dorsal hippocampal damage disrupts the auditory context-dependent attenuation of taste neophobia in mice.

    abstract::Rodents exhibit neophobia for novel tastes, demonstrated by an initial reluctance to drink novel-tasting, potentially-aversive solutions. Taste neophobia attenuates across days if the solution is not aversive, demonstrated by increased consumption as the solution becomes familiar. This attenuation of taste neophobia i...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2018.12.009

    authors: Grau-Perales AB,Levy ERJ,Fenton AA,Gallo M

    更新日期:2019-01-01 00:00:00

  • Extinction and the associative structure of heterogeneous instrumental chains.

    abstract::Drug abuse, overeating, and smoking are all examples of instrumental behaviors that often involve chains or sequences of behavior. A behavior chain is minimally composed of a procurement response that is required in order for a subsequent consumption response to be reinforced. Despite the translational importance of b...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章,评审

    doi:10.1016/j.nlm.2016.06.005

    authors: Thrailkill EA,Bouton ME

    更新日期:2016-09-01 00:00:00

  • Modulation of adenosine signaling prevents scopolamine-induced cognitive impairment in zebrafish.

    abstract::Adenosine, a purine ribonucleoside, exhibits neuromodulatory and neuroprotective effects in the brain and is involved in memory formation and cognitive function. Adenosine signaling is mediated by adenosine receptors (A1, A2A, A2B, and A3); in turn, nucleotide and nucleoside-metabolizing enzymes and adenosine transpor...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2014.11.016

    authors: Bortolotto JW,Melo GM,Cognato Gde P,Vianna MR,Bonan CD

    更新日期:2015-02-01 00:00:00

  • Olfactory discrimination learning in mice lacking the fragile X mental retardation protein.

    abstract::An automated training system was used to compare the behavior of knockout (KO) mice lacking the fragile X mental retardation protein with that of wild-type (WT) mice (C57Bl/6 strain) in the acquisition and retention of olfactory discriminations. KO and WT mice did not differ in the acquisition of a four-stage nose pok...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2008.01.002

    authors: Larson J,Kim D,Patel RC,Floreani C

    更新日期:2008-07-01 00:00:00

  • Isomorphisms between psychological processes and neural mechanisms: from stimulus elements to genetic markers of activity.

    abstract::Traditional learning theory has developed models that can accurately predict and describe the course of learned behavior. These "psychological process" models rely on hypothetical constructs that are usually thought to be not directly measurable or manipulable. Recently, and mostly in parallel, the neural mechanisms u...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2013.10.021

    authors: Fanselow MS,Zelikowsky M,Perusini J,Barrera VR,Hersman S

    更新日期:2014-02-01 00:00:00

  • Propranolol disrupts consolidation of emotional memory in Lymnaea.

    abstract::The therapeutic efficacy of the synthetic β-adrenergic receptor blocker, propranolol, for the treatment of post-traumatic stress disorder (PTSD) is currently being debated. Mixed results have been published regarding propranolol's ability to disrupt the consolidation and reconsolidation of memories. Here, we use the i...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2018.01.010

    authors: Shymansky T,Hughes E,Rothwell CM,Lukowiak K

    更新日期:2018-03-01 00:00:00

  • Differential effects of MDMA and scopolamine on working versus reference memory in the radial arm maze task.

    abstract::Previous research has suggested that the disruption to memory-task performance seen following acute exposure to 3,4-methylenedioxymethaphemtamine (MDMA) with rats might best be characterized as reference memory impairment rather than a working memory impairment. The current study specifically compared the effects of M...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2009.09.005

    authors: Kay C,Harper DN,Hunt M

    更新日期:2010-02-01 00:00:00

  • Coincident induction of long-term facilitation at sensory-motor synapses in Aplysia: presynaptic and postsynaptic factors.

    abstract::Induction of long-term synaptic changes at one synapse can facilitate the induction of long-term plasticity at another synapse. Here we show that if Aplysia sensory neuron (SN) somata and their remote motor neuron (MN) synapses are simultaneously exposed to serotonin (5HT) pulses, which at either site alone are insuff...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.2002.4092

    authors: Sherff CM,Carew TJ

    更新日期:2002-11-01 00:00:00

  • Inactivation of the central nucleus of the amygdala blocks classical conditioning but not conditioning-specific reflex modification of rabbit heart rate.

    abstract::Heart rate (HR) conditioning in rabbits is a widely used model of classical conditioning of autonomic responding that is noted for being similar to the development of conditioned heart rate slowing (bradycardia) in humans. We have shown previously that in addition to HR changes to a tone conditioned stimulus (CS), the...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2012.12.011

    authors: Burhans LB,Schreurs BG

    更新日期:2013-02-01 00:00:00

  • Activation of nociceptin opioid peptide (NOP) receptor impairs contextual fear learning in mice through glutamatergic mechanisms.

    abstract::The present study investigated whether the selective nociceptin opioid peptide (NOP) receptor agonist, Ro64-6198, impairs acquisition of fear conditioning through glutamatergic mechanisms. Systemic administration of Ro64-6198 (0.3 and 1mg/kg) or the non-competitive NMDA receptor antagonist, MK-801 (0.03 and 0.1mg/kg) ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2008.12.001

    authors: Goeldner C,Reiss D,Wichmann J,Kieffer BL,Ouagazzal AM

    更新日期:2009-05-01 00:00:00

  • Mapping number to space in the two hemispheres of the avian brain.

    abstract::Pre-verbal infants and non-human animals associate small numbers with the left space and large numbers with the right space. Birds and primates, trained to identify a given position in a sagittal series of identical positions, whenever required to respond on a left/right oriented series, referred the given position st...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2016.05.010

    authors: Rugani R,Vallortigara G,Regolin L

    更新日期:2016-09-01 00:00:00

  • The effect of amygdala lesions on conditional and unconditional vocalizations in rats.

    abstract::Electrolytic lesions centered on the amygdaloid central nucleus (ACe) resulted in the inability of rats to acquire a Pavlovian conditional vocalization response. Conditioning consisted of pairing a light conditional stimulus with a tailshock unconditional stimulus (US). The thresholds of three unconditional responses ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/s1074-7427(03)00002-9

    authors: Borszcz GS,Leaton RN

    更新日期:2003-05-01 00:00:00

  • Infant visual habituation.

    abstract::The use of visual habituation in the study of infant cognition and learning is reviewed. This article traces the history of the technique, underlying theory, and procedural variation in its measurement. In addition, we review empirical findings with respect to the cognitive processes that presumably contribute to habi...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章,评审

    doi:10.1016/j.nlm.2008.06.002

    authors: Colombo J,Mitchell DW

    更新日期:2009-09-01 00:00:00

  • Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.

    abstract::We evaluated various forms of hippocampus-dependent learning and memory, and hippocampal synaptic plasticity in THY-Tau22 transgenic mice, a murine tauopathy model that expresses double-mutated 4-repeat human tau, and shows neuropathological tau hyperphosphorylation and aggregation throughout the brain. Focussing on h...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2010.12.005

    authors: Van der Jeugd A,Ahmed T,Burnouf S,Belarbi K,Hamdame M,Grosjean ME,Humez S,Balschun D,Blum D,Buée L,D'Hooge R

    更新日期:2011-03-01 00:00:00