Hemorrhagic complications in vein of Galen malformations.

Abstract:

:The authors report on a series of spontaneous intracranial hemorrhages associated with vein of Galen aneurysmal malformations (VGAMs). Thirty-four children with VGAMs have been treated at this institution since 1986. Eight children (24%) harbored the mural-type malformation, and 26 (76%) had the choroidal-type lesion. Two children (25%) with mural lesions and 1 (4%) with a choroidal lesion suffered hemorrhagic complications. Two presented with acute intracranial hemorrhage. A third child developed acute intracranial hemorrhage due to delayed dural sinus thrombosis after endovascular treatment of his choroidal-type VGAM. The subjects ranged in age from 13 days to 17 months at the time of presentation. Each patient underwent rapid radiological evaluation and treatment with endovascular surgery. Post-procedural arteriography demonstrated complete occlusion of the malformation in each patient. For the 3 patients with hemorrhage, follow-up has taken place over 49-, 107-, and 43-month intervals, respectively. Vein of Galen aneurysmal malformations can present with acute intracranial hemorrhage or develop delayed intracranial hemorrhage but respond to treatment using standard endovascular techniques. The presence of hemorrhage does not de facto portend a poor prognosis.

journal_name

Ann Neurol

journal_title

Annals of neurology

authors

Meyers PM,Halbach VV,Phatouros CP,Dowd CF,Malek AM,Lempert TE,Lefler JE,Higashida RT

keywords:

subject

Has Abstract

pub_date

2000-06-01 00:00:00

pages

748-55

issue

6

eissn

0364-5134

issn

1531-8249

journal_volume

47

pub_type

杂志文章
  • Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis.

    abstract::We registered 366 families in a study of dominantly inherited amyotrophic lateral sclerosis. Two hundred ninety families were screened for mutations in the gene encoding copper-zinc cytosolic superoxide dismutase (SOD1). Mutations were detected in 68 families. The most common SOD1 mutation is an alanine for valine sub...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410410212

    authors: Cudkowicz ME,McKenna-Yasek D,Sapp PE,Chin W,Geller B,Hayden DL,Schoenfeld DA,Hosler BA,Horvitz HR,Brown RH

    更新日期:1997-02-01 00:00:00

  • Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease.

    abstract:OBJECTIVE:To understand the mechanisms of skeletal muscle destruction and resistance to enzyme replacement therapy in Pompe disease, a deficiency of lysosomal acid alpha-glucosidase (GAA), in which glycogen accumulates in lysosomes primarily in cardiac and skeletal muscles. METHODS:We have analyzed compartments of the...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.20807

    authors: Fukuda T,Ewan L,Bauer M,Mattaliano RJ,Zaal K,Ralston E,Plotz PH,Raben N

    更新日期:2006-04-01 00:00:00

  • Penumbra detection in acute stroke with perfusion magnetic resonance imaging: Validation with 15 O-positron emission tomography.

    abstract:OBJECTIVE:Accurate identification of the ischemic penumbra, the therapeutic target in acute clinical stroke, is of critical importance to identify patients who might benefit from reperfusion therapies beyond the established time windows. Therefore, we aimed to validate magnetic resonance imaging (MRI) mismatch-based pe...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.25479

    authors: Zaro-Weber O,Fleischer H,Reiblich L,Schuster A,Moeller-Hartmann W,Heiss WD

    更新日期:2019-06-01 00:00:00

  • Recovery of hypermetria after a cerebellar stroke occurs as a multistage process.

    abstract::In a prospective study, we repeatedly recorded fast goal-directed wrist movements of 8 patients who had experienced an acute cerebellar hypermetria due to a stroke and who had subsequently recovered clinically. Movements and the associated agonist and antagonist electromyographic (EMG) activities were recorded before ...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410380314

    authors: Manto M,Jacquy J,Hildebrand J,Godaux E

    更新日期:1995-09-01 00:00:00

  • Assessment of genetic risk for Alzheimer's disease among first-degree relatives.

    abstract::Life table methods were used to determine the relative risk of Alzheimer's disease (AD) in relatives of index cases with AD. Risk of AD was assessed in 967 first-degree relatives of 128 probands with clinically diagnosed AD and 572 first-degree relatives of a control group consisting of 84 subjects with Parkinson's di...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410250511

    authors: Farrer LA,O'Sullivan DM,Cupples LA,Growdon JH,Myers RH

    更新日期:1989-05-01 00:00:00

  • Encephalitis among Cree children in northern Quebec.

    abstract::We report a neurological disease among Cree Indian children in a northern Quebec village. The disease manifests as severe mental retardation, cerebral atrophy with white matter changes and calcifications, and systemic immunological abnormalities. Eleven cases are known in five families. The familial incidence of cases...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410240402

    authors: Black DN,Watters GV,Andermann E,Dumont C,Kabay ME,Kaplan P,Meagher-Villemure K,Michaud J,O'Gorman G,Reece E

    更新日期:1988-10-01 00:00:00

  • Sensorimotor disinhibition in Parkinson's disease: effects of levodopa.

    abstract::It has been known for some time that patients with Parkinson's disease (PD) have difficulty executing simultaneous motor acts, yet the pathophysiology underlying this impairment remains uncertain. We examined the possibility that these dual-task deficits stem from defective sensorimotor mechanisms producing interferen...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410310110

    authors: Caligiuri MP,Heindel WC,Lohr JB

    更新日期:1992-01-01 00:00:00

  • Strategic Considerations for Applying the Flipped Classroom to Neurology Education.

    abstract::Nowadays, the "flipped classroom" approach is taking the center stage within medical education. However, very few reports on the implementation of the flipped classroom in neurology have been published to date, and this educational model still represents a challenge for students and educators alike. In this article, n...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.25609

    authors: Sandrone S,Berthaud JV,Carlson C,Cios J,Dixit N,Farheen A,Kraker J,Owens JWM,Patino G,Sarva H,Weber D,Schneider LD

    更新日期:2020-01-01 00:00:00

  • Cerebellar outflow lesions: a comparison of movement deficits resulting from lesions at the levels of the cerebellum and thalamus.

    abstract::Previous work has shown that lesions in the lateral cerebellum involving the dentate nucleus impair both reaching and pinching movements in humans and monkeys. This study addressed the question of whether disruption of the cerebellar-thalamo-cortical pathway at the level of the thalamus would produce behavioral defici...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410380608

    authors: Bastian AJ,Thach WT

    更新日期:1995-12-01 00:00:00

  • Tissue acid-base balance and oxygen metabolism in human cerebral infarction studied with positron emission tomography.

    abstract::Nine patients who had suffered strokes were examined between 10 and 34 days after onset using positron emission tomography. DMO labeled with carbon 11 was used to evaluate brain acid-base balance, and the oxygen-15 inhalation technique was used to measure regional cerebral blood flow, the oxygen extraction fraction, a...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410140405

    authors: Syrota A,Castaing M,Rougemont D,Berridge M,Baron JC,Bousser MG,Pocidalo JJ

    更新日期:1983-10-01 00:00:00

  • Changes in excitability of motor cortical circuitry in patients with Parkinson's disease.

    abstract::Using the technique of transcranial magnetic stimulation over the motor areas of cortex and recording electromyographic (EMG) responses from the first dorsal interosseous muscle, we measured the excitability of corticocortical inhibitory circuits at rest using a double pulse paradigm, in 11 patients with Parkinson's d...

    journal_title:Annals of neurology

    pub_type: 临床试验,杂志文章

    doi:10.1002/ana.410370208

    authors: Ridding MC,Inzelberg R,Rothwell JC

    更新日期:1995-02-01 00:00:00

  • Nonconvulsive status epilepticus following cerebral angiography.

    abstract::A 64-year-old man developed lethargy and aphasia immediately following cerebral arteriography with iothalamate meglumine. An electroencephalogram showed continuous epileptiform activity. The patient was treated with intravenous phenytoin with complete resolution of clinical symptoms and electroencephalographic epilept...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410250217

    authors: Vickrey BG,Bahls FH

    更新日期:1989-02-01 00:00:00

  • Pituitary dysfunction after blast traumatic brain injury: The UK BIOSAP study.

    abstract:OBJECTIVE:Pituitary dysfunction is a recognized consequence of traumatic brain injury (TBI) that causes cognitive, psychological, and metabolic impairment. Hormone replacement offers a therapeutic opportunity. Blast TBI (bTBI) from improvised explosive devices is commonly seen in soldiers returning from recent conflict...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.23958

    authors: Baxter D,Sharp DJ,Feeney C,Papadopoulou D,Ham TE,Jilka S,Hellyer PJ,Patel MC,Bennett AN,Mistlin A,McGilloway E,Midwinter M,Goldstone AP

    更新日期:2013-10-01 00:00:00

  • Adrenoleukodystrophy: a correlation between saturated very long-chain fatty acids in mononuclear cells and phenotype.

    abstract::Saturated very long-chain fatty acids in erythrocyte membranes, blood plasma, and mononuclear cells were studied in 4 patients with childhood-adolescent adrenoleukodystrophy and 4 patients with adult adrenoleukodystrophy and 19 normal control subjects by using high-performance liquid chromatography. Ratios of C26:0 to...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410300118

    authors: Antoku Y,Koike F,Ohtsuka Y,Sakai T,Tsukamoto K,Nagara H,Iwashita H,Goto I

    更新日期:1991-07-01 00:00:00

  • Phenobarbital modifies seizure-related brain injury in the developing brain.

    abstract::To investigate the potential role of drug therapy in preventing or exacerbating seizure-related brain injury in the prepubescent brain, we administered kainic acid to rats at postnatal day 35. Therapy with daily phenobarbital was started directly before or 1 day after kainic acid was administered, and was continued th...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410360314

    authors: Mikati MA,Holmes GL,Chronopoulos A,Hyde P,Thurber S,Gatt A,Liu Z,Werner S,Stafstrom CE

    更新日期:1994-09-01 00:00:00

  • Sensory discrimination capabilities in patients with focal hand dystonia.

    abstract::To explore the concept that dystonia may result from dysfunction of the sensory system, 14 patients with focal hand dystonia were tested during two somatosensory discrimination tasks. Compared with controls, patients had a higher threshold in a task involving discrimination of two electric stimuli closely related temp...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:

    authors: Bara-Jimenez W,Shelton P,Sanger TD,Hallett M

    更新日期:2000-03-01 00:00:00

  • Evoked potential abnormalities in the various inherited ataxias.

    abstract::Visual (VEP), brainstem auditory (BAEP), and somatosensory (SEP) evoked potential tests were performed in 45 patients representing ten types of inherited disorders in which ataxia was the most prominent symptom. Comparable VEP abnormalities were present among all types of patients. Normal BAEP tests were recorded in m...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410130106

    authors: Nuwer MR,Perlman SL,Packwood JW,Kark RA

    更新日期:1983-01-01 00:00:00

  • Internal globus pallidus discharge is nearly suppressed during levodopa-induced dyskinesias.

    abstract::The functional status of the globus pallidus internal segment (GPi) plays a key role in mediating the effects of antiparkinsonian drugs. During long-term levodopa therapy, patients develop abnormal movements, dyskinesias, the pathophysiological basis of which is poorly understood. We recorded single cells in the GPi o...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/1531-8249(199911)46:5<732::aid-ana8>3.0.co

    authors: Papa SM,Desimone R,Fiorani M,Oldfield EH

    更新日期:1999-11-01 00:00:00

  • Does a defect of energy metabolism in the nerve fiber underlie axonal degeneration in polyneuropathies?

    abstract::A number of chemically unrelated neurotoxic compounds and several types of metabolic abnormalities cause strikingly similar patterns of distal symmetrical polyneuropathy in humans and animals. Experimental studies with laboratory species have demonstrated that many toxic polyneuropathies are associated with distal and...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410050602

    authors: Spencer PS,Sabri MI,Schaumburg HH,Moore CL

    更新日期:1979-06-01 00:00:00

  • Necrotizing arteritis and spinal subarachnoid hemorrhage in Sjögren syndrome.

    abstract::A 37-year-old woman with primary Sjögren syndrome developed mixed cryoglobulinemia and systemic vasculitis. Subarachnoid hemorrhage occurred as a result of necrotizing anterior spinal arteritis. Although rarely seen in mixed cryoglobulinemia, central nervous system complications have recently been documented in Sjögre...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410110614

    authors: Alexander EL,Craft C,Dorsch C,Moser RL,Provost TT,Alexander GE

    更新日期:1982-06-01 00:00:00

  • Relationship of the extended tau haplotype to tau biochemistry and neuropathology in progressive supranuclear palsy.

    abstract::Two extended haplotypes of the tau gene (H1 and H2) have been described. The frequency of H1 haplotype is increased in progressive supranuclear palsy (PSP). PSP is associated with filamentous tau lesions in neurons and glia, which are reportedly composed exclusively of tau isoforms with four repeats in the microtubule...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.1159

    authors: Liu WK,Le TV,Adamson J,Baker M,Cookson N,Hardy J,Hutton M,Yen SH,Dickson DW

    更新日期:2001-10-01 00:00:00

  • Infarction of the conus medullaris.

    abstract::We describe 5 patients who presented with an acute cauda equina syndrome, which we believe was due to infarction of the conus medullaris. In 3 patients, the onset was spontaneous, and in 2 patients it was secondary to temporary occlusion of the distal aorta during medical manipulation. Pain in the buttocks and posteri...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410210510

    authors: Anderson NE,Willoughby EW

    更新日期:1987-05-01 00:00:00

  • Motor nerve biopsy: clinical usefulness and histopathological criteria.

    abstract::Early differential diagnosis of motor neuropathies (MN) and lower motor neuron diseases (LMND) is important, as prognosis and therapeutic approaches are different. We evaluated the diagnostic contribution of the biopsy of the motor branch of the obturator nerve and gracilis muscle in 21 consecutive patients in which, ...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.22110

    authors: Riva N,Iannaccone S,Corbo M,Casellato C,Sferrazza B,Lazzerini A,Scarlato M,Cerri F,Previtali SC,Nobile-Orazio E,Comi G,Quattrini A

    更新日期:2011-01-01 00:00:00

  • Quantitative analysis of cortical pyramidal neurons after corpus callosotomy.

    abstract::This study quantitatively explored the dendritic/spine extent of supragranular pyramidal neurons across several cortical areas in two adult male subjects who had undergone a callosotomy several decades before death. In all cortical areas, there were numerous atypical, supragranular pyramidal neurons with elongated "ta...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.10620

    authors: Jacobs B,Creswell J,Britt JP,Ford KL,Bogen JE,Zaidel E

    更新日期:2003-07-01 00:00:00

  • Effect of epilepsy magnetic source imaging on intracranial electrode placement.

    abstract:OBJECTIVE:Intracranial electroencephalography (ICEEG) with chronically implanted electrodes is a costly invasive diagnostic procedure that remains necessary for a large proportion of patients who undergo evaluation for epilepsy surgery. This study was designed to evaluate whether magnetic source imaging (MSI), a noninv...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.21660

    authors: Knowlton RC,Razdan SN,Limdi N,Elgavish RA,Killen J,Blount J,Burneo JG,Ver Hoef L,Paige L,Faught E,Kankirawatana P,Bartolucci A,Riley K,Kuzniecky R

    更新日期:2009-06-01 00:00:00

  • Positron emission tomographic studies in aging and cerebrovascular disease at Hammersmith hospital.

    abstract::This paper attempts to place into perspective the present state of clinical investigation with PET in neurology. To this end we briefly review the work of the neurology group of the MRC Cyclotron Unit at Hammersmith Hospital, by reference to studies performed in normal subjects and in patients with cerebrovascular dis...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410150722

    authors: Frackowiak RS,Wise RJ,Gibbs JM,Jones T

    更新日期:1984-01-01 00:00:00

  • Altered synaptic organization in facial nucleus following facial nerve regeneration: an electrophysiological study in man.

    abstract::Seven patients with postfacial palsy contracture and mass contractions were investigated electrophysiologically. In 3 patients the early blink reflex showed an unusually high amplitude, which can be attributed to enhanced excitability of facial motor neurons. In 5 patients the early blink reflex had acquired a crossed...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410020114

    authors: Bratzlavsky M,vander Eecken H

    更新日期:1977-07-01 00:00:00

  • Abnormal electrical brain responses to pitch in congenital amusia.

    abstract::Congenital amusia is a lifelong disability that prevents afflicted individuals from enjoying music as ordinary people do. The deficit is limited to music and cannot be explained by prior brain lesion, hearing loss, or any cognitive or socio-affective disturbance. Recent behavioral results suggest that this disorder is...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.20606

    authors: Peretz I,Brattico E,Tervaniemi M

    更新日期:2005-09-01 00:00:00

  • Successful treatment with tocainide of recessive generalized congenital myotonia.

    abstract::A patient with recessive generalized congenital myotonia and severe, disabling weakness underwent various forms of treatment while being monitored electrophysiologically. Phenytoin, verapamil, and acetazolamide were ineffective, but tocainide yielded good results. Improvement was dose-dependent, and was limited by irr...

    journal_title:Annals of neurology

    pub_type: 杂志文章

    doi:10.1002/ana.410190515

    authors: Streib EW

    更新日期:1986-05-01 00:00:00

  • Novel approaches and challenges to treatment of central nervous system viral infections.

    abstract::Existing and emerging viral central nervous system (CNS) infections are major sources of human morbidity and mortality. Treatments of proven efficacy are currently limited predominantly to herpesviruses and human immunodeficiency virus (HIV). Development of new therapies has been hampered by the lack of appropriate an...

    journal_title:Annals of neurology

    pub_type: 杂志文章,评审

    doi:10.1002/ana.23988

    authors: Nath A,Tyler KL

    更新日期:2013-09-01 00:00:00