HIV therapy in the post-eradication era.

Abstract:

:Over the past three years, most efforts of virologists and immunologists involved in the field of Human Immunodeficiency Virus (HIV) have been focussed on strategies aimed at eradicating the infection. So far, however, all the approaches have been unsuccessful. Indeed, even if the currently available potent antiretroviral regimens are able to induce a profound and durable suppression of viral replication, they have poor effect on a viral reservoir of latently infected CD4+ T lymphocytes that rapidly reactivate after treatment discontinuation. Different approaches, including combined (immune based and antiretroviral) therapies, are therefore under investigation. The goal is to achieve an equilibrium where virus-induced immune dysfunction is prevented by an effective anti HIV immune response.

authors

Vella S,Palmisano L

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

34-7

issue

1

eissn

0393-974X

issn

1724-6083

journal_volume

14

pub_type

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