Developmental outcome of neonatal intensive care: what questions are we asking?

abstract：PURPOSE OF REVIEW:This article reviews three common abnormalities requiring surgical treatment in adults with congenital heart disease (CHD): Ebstein's anomaly, the failing Fontan, and pulmonary valve disease. RECENT FINDINGS:As of 2000, more adults than children are alive with CHD. Each year, more of these adults wit...

journal_title：Current opinion in pediatrics

authors： Dearani JA,Mavroudis C,Quintessenza J,Deal BJ,Backer CL,Fitzgerald P,Connolly HM,Jacobs JP

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review describes recent advances and unique challenges in precision medicine for pediatric cancers and highlights clinical trials assessing the clinical impact of targeted therapy matched to molecular alterations identified by tumor profiling. RECENT FINDINGS:Multiple prospective clinical...

journal_title：Current opinion in pediatrics

authors： Forrest SJ,Geoerger B,Janeway KA

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Anemia and thrombocytopenia are the most common hematological problems in neonates. Red blood cell (RBC) and platelet transfusions are the mainstays of therapy, but data to guide neonatal transfusion practices have been sparse. Recombinant hematopoietic growth factors represent another therapeutic alt...

journal_title：Current opinion in pediatrics

authors： Sallmon H,Sola-Visner M

更新日期：2012-02-01 00:00:00

abstract：:Infectious disease emergencies are those in which delays in diagnosis or treatment may lead to untoward harm. Recent developments in the field offer few new therapies, but rather emphasize familiar infections in new guises or clarify approaches to troublesome entities. An enduring concern for the legal risks implicit ...

journal_title：Current opinion in pediatrics

authors： Radetsky M

更新日期：1994-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Children with medical or surgical critical illness or injury require skillful attention to physical, emotional, psychological, and spiritual needs, whereas their families need support and guidance in facing life-threatening or life-changing events and gut-wrenching decisions. This article reviews curr...

journal_title：Current opinion in pediatrics

authors： Rothschild CB,Derrington SF

更新日期：2020-06-01 00:00:00

abstract：:Slipped capital femoral epiphysis remains a diagnostic problem despite numerous papers written on the subject. The most important factor in the diagnosis of slipped capital femoral epiphysis is suspicion by the practitioner. The history, physical examination, and radiographic imaging are important in the confirmation ...

journal_title：Current opinion in pediatrics

authors： Reynolds RA

更新日期：1999-02-01 00:00:00

abstract：:Hypoxic-ischemic brain injury occurs frequently in infancy and childhood. Events such as perinatal asphyxia, near drowning, respiratory arrest, and near sudden infant death syndrome cause significant mortality and morbidity. Despite current critical care practices, the outcomes from such injuries may be life-long neur...

journal_title：Current opinion in pediatrics

authors： Biagas K

更新日期：1999-06-01 00:00:00

abstract：PURPOSE OF REVIEW:We present data from recently conducted research on the diagnosis and management of skin and soft tissue infections (SSTIs) in children. RECENT FINDINGS:Current research in the area of SSTIs (cellulitis and abscess) has focused on the use of ultrasound, risk factors associated with bacteremia, antibi...

journal_title：Current opinion in pediatrics

authors： Fenster DB,Renny MH,Ng C,Roskind CG

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Physical activity has been highlighted internationally as a beneficial intervention for weight control and the improvement of physical and mental health. This review highlights findings from recent literature to guide office-based promotion of physical activity for obesity treatment and prevention. R...

journal_title：Current opinion in pediatrics

authors： Floriani V,Kennedy C

更新日期：2007-02-01 00:00:00

abstract：:Bone marrow transplantation has become well established in the treatment of malignant and nonmalignant disorders. Steady progress continues in improving survival after transplantation, but many problems remain to be solved. Relapsed disease is a major limitation, and new, more intensive preparative regimens are being ...

journal_title：Current opinion in pediatrics

authors： Robertson KA

更新日期：1993-02-01 00:00:00

abstract：:Preimplantation genetic diagnosis now represents an alternative reproductive option for parents at high risk of having offspring affected with certain genetic diseases. Progress in the past year has included increasing reliability in embryo sexing by both polymerase chain reaction and fluorescent in situ hybridization...

journal_title：Current opinion in pediatrics

authors： Black SH

更新日期：1994-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonaccidental trauma and neglect continue to be major problems for children, families, and the providers who care for them. Whereas prevention is the key to ending child abuse and neglect, diagnosis and treatment continue to be the mainstays of practice. This article will briefly review the epidemiolo...

journal_title：Current opinion in pediatrics

authors： Tenney-Soeiro R,Wilson C

更新日期：2004-04-01 00:00:00

abstract：:This review summarizes recent literature regarding the clinical and molecular features of nonmalignant leukocyte disorders in children. Leukocyte adhesion deficiency and chronic granulomatous disease, two inherited disorders of neutrophil function, continue to be the best-characterized disorders with respect to specif...

journal_title：Current opinion in pediatrics

authors： Dinauer MC

更新日期：1993-02-01 00:00:00

abstract：:Tarsal coalition is a common abnormality of the hindfoot skeleton that only rarely leads to symptoms. These symptoms occur most commonly in adolescence but rarely can be found also in adults. Although most coalitions are congenital, as the consequence of autosomal dominant inheritance, coalitions also can be acquired ...

journal_title：Current opinion in pediatrics

authors： Bohne WH

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This study reviews the history of neonatal drug development, recent legislative efforts designed to facilitate the study of therapeutic agents in neonates, and future steps necessary to advance drug development. RECENT FINDINGS:Although many federal regulations have been introduced over the past 15 y...

journal_title：Current opinion in pediatrics

authors： Smith AM,Davis JM

更新日期：2017-04-01 00:00:00

abstract：:In the past decade a number of studies have systematically addressed the questions that existed regarding optimal ways to rehydrate and then refeed infants and children with diarrhea. Two very thorough papers are the highlights of the past year's publications in the topic of acute gastroenteritis in children. One summ...

journal_title：Current opinion in pediatrics

authors： Lifschitz CH

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disorder involving benign growths in multiple organ systems of affected patients. Variable phenotypes from mild to severe have been reported for related as well as unrelated patients affected by TSC. The two causative genes, TSC1...

journal_title：Current opinion in pediatrics

authors： Au KS,Ward CH,Northrup H

更新日期：2008-12-01 00:00:00

abstract：:The atopic diseases of childhood consist of the triad of asthma, allergic rhinitis, and atopic dermatitis. All share a common pathogenesis, being mediated by IgE, and are frequently present together in the same individual and family. These disorders and their comorbidities comprise a large component of general pediatr...

journal_title：Current opinion in pediatrics

authors： Stone KD

更新日期：2002-10-01 00:00:00

abstract：:A number of growth factors have been identified that participate in lung growth and repair. The early stages of the repair cascade are important in preventing the later development of fibrosis. Both transforming growth factor-beta and basic fibroblast growth factor can have beneficial effects when given early in some ...

journal_title：Current opinion in pediatrics

authors： Perkett EA

更新日期：1995-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent progress in our understanding of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders. RECENT FINDINGS:A number of Mendelian disorders of immune dysregulation and autoimmunity have been noted to result from defects in T regulatory cell,...

journal_title：Current opinion in pediatrics

authors： Verbsky JW,Chatila TA

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Prenatal genetic screening and diagnostic testing can identify many disorders that will require specialized newborn care and follow-up. Pediatricians should be aware of recent advances in testing that may have implications for their patients and families. RECENT FINDINGS:Over the last half decade, th...

journal_title：Current opinion in pediatrics

authors： Cunniff C,Hudgins L

更新日期：2010-12-01 00:00:00

abstract：:Outcomes for infants with gastroschisis have paralleled advances made in neonatal intensive care and the use of parenteral nutrition. Mortality rates approaching 100% a half century ago are now closer to 2% to 8%. Further reduction in morbidity has been the focus of many studies during the past decade. Efforts have be...

journal_title：Current opinion in pediatrics

authors： Schlatter M

更新日期：2003-06-01 00:00:00

abstract：:Increasing levels of stress in the daily lives of adolescents is an important health concern. Adolescents experience a variety of stressful situations and use a wide range of coping strategies to help effectively manage stress. Recent research on adolescent coping with stressful situations is reviewed. Findings suppor...

journal_title：Current opinion in pediatrics

authors： Bonica C,Daniel JH

更新日期：2003-08-01 00:00:00

abstract：:In the 7 years since the cystic fibrosis (CF) gene has been cloned, many experimental trials of population screening for CF heterozygotes have been reported. Targeting young adults near reproductive age has shown that the method in which screening is offered is a major determinant of acceptance rates: personal invitat...

journal_title：Current opinion in pediatrics

authors： Brock DJ

更新日期：1996-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The literature was reviewed to describe the role of gait analysis in the orthopaedic management of ambulatory children with cerebral palsy and examine the current best evidence to support these roles. RECENT FINDINGS:Gait laboratory analysis is superior to visual or observational analysis of gait bec...

journal_title：Current opinion in pediatrics

authors： Narayanan UG

更新日期：2007-02-01 00:00:00

abstract：:Over the past several years, many new strategies have evolved for improving the care of patients with acute lung injury and respiratory failure. Although many of these new modalities remain unproven, some show much promise for decreasing the morbidity and mortality seen in critically ill patients who need assisted ven...

journal_title：Current opinion in pediatrics

authors： Donnelly KM,Bogue CW

更新日期：1998-06-01 00:00:00

abstract：:Cutaneous reactions to penicillin-type antibiotics are usually caused by IgE-mediated reactions directed toward the beta-lactam ring (in penicillin, ampicillin-amoxicillin, and cephalosporins). These allergic reactions may be reliably diagnosed (96% to 99% of the time) with a battery of skin tests derived from penicil...

journal_title：Current opinion in pediatrics

authors： Anderson JA

更新日期：1994-12-01 00:00:00

abstract：:Thrombopoietin is a hematopoietic growth factor that stimulates megakaryopoiesis. Recent results indicate that thrombopoietin has multilineage hematopoietic effects both in vitro and in vivo. Clinical studies of thrombopoietin have begun, and are reviewed. ...

journal_title：Current opinion in pediatrics

authors： Broudy VC,Kaushansky K

更新日期：1998-02-01 00:00:00

abstract：:A rapidly accelerating number of transplantations of hematopoietic stem cells from human umbilical cord blood have been performed for malignancies and for congenital disorders. Umbilical cord blood presents multiple advantages over bone marrow as a source of stem cells. Harvesting presents no donor risk or discomfort,...

journal_title：Current opinion in pediatrics

authors： Newburger PE,Quesenberry PJ

更新日期：1996-02-01 00:00:00

abstract：:The importance of pediatric interhospital transport has increased dramatically in the past 5 to 10 years. Reasons include improved capabilities of tertiary care centers receiving transported patients, advances in availability of portable equipment that functions well in moving vehicles, and widespread recognition that...

journal_title：Current opinion in pediatrics

authors： McCloskey KA

更新日期：1996-06-01 00:00:00