Role of motility in adherence to and invasion of a fish cell line by Vibrio anguillarum.

Abstract:

:To understand further the role of the flagellum of Vibrio anguillarum in virulence, invasive and adhesive properties of isogenic motility mutants were analyzed by using a chinook salmon embryo cell line. Adhesion was unaffected but invasion of the cell line was significantly decreased in nonmotile or partially motile mutants, and the chemotactic mutant was hyperinvasive. These results suggest that active motility aids invasion by V. anguillarum, both in vivo and in vitro.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Ormonde P,Hörstedt P,O'Toole R,Milton DL

doi

10.1128/jb.182.8.2326-2328.2000

keywords:

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

2326-8

issue

8

eissn

0021-9193

issn

1098-5530

journal_volume

182

pub_type

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