High-resolution intersubject averaging and a coordinate system for the cortical surface.

Abstract:

:The neurons of the human cerebral cortex are arranged in a highly folded sheet, with the majority of the cortical surface area buried in folds. Cortical maps are typically arranged with a topography oriented parallel to the cortical surface. Despite this unambiguous sheetlike geometry, the most commonly used coordinate systems for localizing cortical features are based on 3-D stereotaxic coordinates rather than on position relative to the 2-D cortical sheet. In order to address the need for a more natural surface-based coordinate system for the cortex, we have developed a means for generating an average folding pattern across a large number of individual subjects as a function on the unit sphere and of nonrigidly aligning each individual with the average. This establishes a spherical surface-based coordinate system that is adapted to the folding pattern of each individual subject, allowing for much higher localization accuracy of structural and functional features of the human brain.

journal_name

Hum Brain Mapp

journal_title

Human brain mapping

authors

Fischl B,Sereno MI,Tootell RB,Dale AM

doi

10.1002/(sici)1097-0193(1999)8:4<272::aid-hbm10>3.

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

272-84

issue

4

eissn

1065-9471

issn

1097-0193

pii

10.1002/(SICI)1097-0193(1999)8:4<272::AID-HBM10>3.

journal_volume

8

pub_type

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