Abstract:
:The neurons of the human cerebral cortex are arranged in a highly folded sheet, with the majority of the cortical surface area buried in folds. Cortical maps are typically arranged with a topography oriented parallel to the cortical surface. Despite this unambiguous sheetlike geometry, the most commonly used coordinate systems for localizing cortical features are based on 3-D stereotaxic coordinates rather than on position relative to the 2-D cortical sheet. In order to address the need for a more natural surface-based coordinate system for the cortex, we have developed a means for generating an average folding pattern across a large number of individual subjects as a function on the unit sphere and of nonrigidly aligning each individual with the average. This establishes a spherical surface-based coordinate system that is adapted to the folding pattern of each individual subject, allowing for much higher localization accuracy of structural and functional features of the human brain.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Fischl B,Sereno MI,Tootell RB,Dale AMdoi
10.1002/(sici)1097-0193(1999)8:4<272::aid-hbm10>3.keywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
272-84issue
4eissn
1065-9471issn
1097-0193pii
10.1002/(SICI)1097-0193(1999)8:4<272::AID-HBM10>3.journal_volume
8pub_type
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