Abstract:
PURPOSE:High resolution MR images obtained from a normal human volunteer at 8 T are utilized to describe the appearance of iron-containing deep gray nuclei at this field strength. METHOD:High resolution (1,024 x 1,024 matrix) near-axial gradient echo images of the deep gray nuclei were acquired on a human volunteer by using an 8 T scanner. The images were acquired using a transverse electromagnetic resonator operating in quadrature. The following parameters were utilized: TR = 750 ms, TE = 17 ms, flip angle = 45 degrees, receiver bandwidth = 50 kHz, slice thickness = 2 mm, FOV = 20 cm. The 8 T images were reviewed and correlated to the known anatomy of the deep nuclei by comparing them with images observed at lower field strength, published diagrams, and histologic sections. In addition, the appearance of the nuclei was related to the known imaging characteristics of brain iron at lower fields. RESULTS:The caudate, globus pallidus, putamen, thalami, substantia nigra, and red nuclei were clearly identified. The structures with the highest levels of iron, the globus pallidus, substantia nigra, and red nuclei, demonstrated significantly decreased signal, providing a map of iron distribution in the human brain. CONCLUSION:Preliminary imaging at 8 T demonstrates the ability to acquire ultra high resolution images of the deep nuclei, with signal characteristics believed to represent the distribution of brain iron. This may prove to be important in the early diagnosis of several neurodegenerative disorders.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Bourekas EC,Christoforidis GA,Abduljalil AM,Kangarlu A,Chakeres DW,Spigos DG,Robitaille PMdoi
10.1097/00004728-199911000-00009keywords:
subject
Has Abstractpub_date
1999-11-01 00:00:00pages
867-74issue
6eissn
0363-8715issn
1532-3145journal_volume
23pub_type
杂志文章abstract::We report a unique case of early-phase Takayasu arteritis in which the vessels demonstrated accumulation of [18F]fluorodeoxyglucose (FDG) on PET scanning. This observation suggests the possible use of FDG-PET for the diagnosis of vasculitis. Early diagnosis of Takayasu arteritis may permit early treatment and possibly...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199901000-00004
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To describe computed tomography (CT) findings of invasive carcinoma derived from intraductal papillary mucinous neoplasms (IPMNs) of the pancreas during long-term follow-up. METHODS:Follow-up CT findings of 5 patients with IPMNs progressing to invasive carcinomas were respectively reviewed for 12 to 63 month...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000220801.76276.0f
更新日期:2006-11-01 00:00:00
abstract::Volume rendering is a visualization technique that has important applications in diagnostic radiology and radiotherapy. A methodology is presented for (a) evaluation of the quantitative accuracy of representation of known objects in volume-rendered scenes and for (b) optimization of the opacity transfer function to ac...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199805000-00020
更新日期:1998-05-01 00:00:00
abstract::Several classification systems for neuroendocrine tumors (NETs) exist, which use variable terminology and criteria for grading and staging. This variability in terminology can cause confusion and difficulty in recognizing which tumors are, in fact, members of this heterogeneous group of malignancies. The largest group...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0000000000000140
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To describe the computed tomography (CT) and magnetic resonance imaging (MRI) findings of solid organizing hepatic abscesses and correlate them with the pathologic findings. METHODS:Ten patients with 10 pathologically proven solid organizing hepatic abscesses who underwent 3-phase CT (n = 10) or MRI (n = 7) ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200603000-00004
更新日期:2006-03-01 00:00:00
abstract::This report describes the imaging findings of the first reported case of a bronchobiliary fistula that developed as a complication of liver transplantation. The diagnosis was confirmed by the aspiration of bile from the bronchus. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000131583.52386.cf
更新日期:2004-09-01 00:00:00
abstract::The CT findings in hepatic involvement by Echinococcus granulosus are described. Pathognomonic signs of the hydatid nature of a cystic lesion are visualization of the cystic wall on plain CT, calcification of the cyst wall, daughter cysts, and membrane detachment. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198410000-00005
更新日期:1984-10-01 00:00:00
abstract::A 45-year-old patient with focal intrahepatic extramedullary hematopoiesis is presented in which the liver was imaged by CT, ultrasound, and MR. The appearance of the lesions on MR consisted of slightly increased signal on T2-weighted images with heterogeneous enhancement of some of the lesions during bolus infusion o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::Diffuse cavernous hemangioma of the rectosigmoid colon (DCHR) is an uncommon disease that affects mainly young adults. As the main symptom is non-specific chronic rectal bleeding, the clinical diagnosis is difficult and often delayed. In this essay, we illustrate the imaging features of DCHR, including plain radiograp...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199811000-00002
更新日期:1998-11-01 00:00:00
abstract::The purpose of this report is to describe a further distinctive cause of crazy-paving pattern on thin-section computed tomography in a patient affected by pulmonary granulomatous mycosis fungoides. It was possible to reconcile the crazy-paving appearance on thin-section computed tomography scan with the histopathologi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000214269.72180.64
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To determine the feasibility of diffusion-weighted magnetic resonance (MR) imaging (DWI) of uterine cervical cancer and to investigate whether the apparent diffusion coefficient (ADC) values of cervical cancer differ from those of normal cervix and whether they could indicate the histologic type and the patholo...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31819e93af
更新日期:2009-11-01 00:00:00
abstract::Computed tomography (CT) findings in hydatid disease (echinococciasis) of the liver are described. Disease was caused by Echinococcus granulosus (n = 8) or E. alveolaris (n = 5), respectively. The CT appearance of these two types of echinococciasis is quite different; in disease caused by E. granulosus the CT appearan...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197811000-00018
更新日期:1978-11-01 00:00:00
abstract::Compressive sensing (CS)-based interior tomography is a state-of-the-art method for accurate image reconstruction from only locally truncated projections. Here, we report our preliminary interior tomography results reconstructed from raw projections of a patient acquired on a GE Discovery CT750 HD scanner. This is the...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318231c578
更新日期:2011-11-01 00:00:00
abstract::Small aortas were documented by CT in six patients, 16-34 years old. The diameter of these aortas measured at the level of 1 cm below the orifice of the superior mesenteric artery ranged from 10 to 12 mm, much smaller than the mean of 17 mm obtained from 20 subjects, 16-20 years old. Such small aortas are usually prod...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To verify the earliest detectability of liver metastases in patients who underwent serial multidetector computed tomography (MDCT) examinations. METHODS:We selected 12 patients with known primary cancer who underwent 4 or more contrast-enhanced, 4-detector MDCTs. When metastases had been reported, an evaluat...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200605000-00006
更新日期:2006-05-01 00:00:00
abstract::In a prospective clinical study, 26 patients (22 with malignant lymphoma and 4 with myelofibrosis) and 9 healthy volunteers were examined by conventional magnetic resonance and proton chemical shift imaging (CSI; modified Dixon method). On the basis of the CSI data, a quantitative evaluation of the relative fat and wa...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199007000-00023
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVE:The purpose of our study was to quantify peritumoral brain edema (PTE) in vivo using NMR relaxation time imaging, as the longitudinal relaxation time T1 is proportional to tissue water content, and to use the method for monitoring the effects of glucocorticoids (GCCs) on PTE in brain tumor patients as a funct...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199407000-00001
更新日期:1994-07-01 00:00:00
abstract::Coronary artery disease is currently the largest killer in the western world, and is estimated to become the leading cause of death worldwide by the year 2020. The question therefore is whether magnetic resonance imaging currently has a place in the already extremely well equipped armamentarium of cardiac testing. Alt...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-199911001-00019
更新日期:1999-11-01 00:00:00
abstract::A case of superficial siderosis of the central nervous system secondary to bleeding from an ependymoma is presented. High-field magnetic resonance imaging showed marginal hypointensity of the cervical cord, medulla oblongata, pons, mesencephalon, anterior cerebellar and basal cerebral surfaces, and cranial nerves (II,...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198509000-00029
更新日期:1985-09-01 00:00:00
abstract::The CT findings of multiple lipid-containing dermal cysts in a patient with steatocystoma multiplex are presented. The characteristic locations, shapes, and densities of the cysts in this rare skin disorder are discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198603000-00043
更新日期:1986-03-01 00:00:00
abstract:BACKGROUND AND AIMS:To prospectively determine the accuracy of liver fat quantification with magnetic resonance imaging (MRI). PATIENTS AND METHODS:The population consisted of 40 patients (mean age, 52.5 years; range, 23-78 years). The same day, all patients underwent MRI and ultrasonography-guided liver biopsy. The h...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318199d883
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:Our goal was to assess the utility of different imaging directions in volumetric studies of the heart with MRI, in particular to identify the optimal imaging plane for studies of the right ventricle. METHOD:We examined 12 sets of human four-chamber cadaveric cardiac casts. Gradient echo MRI was performed in fo...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199811000-00012
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare image quality for abdominal computed tomographic (CT) images acquired at 200 and 50 mA s and reconstructed with image-based iterative reconstruction. MATERIALS AND METHODS:In this institutional review board-approved prospective study, 22 patients (mean [SD] age, 64....
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182a17629
更新日期:2014-01-01 00:00:00
abstract::The utility of gadolinium-enhanced ultrafast MR imaging in the diagnosis of focal nodular hyperplasia (FNH) of the liver was assessed in one patient. Contrast-enhanced serial snapshot-FLASH with a frequency of 30 images/min demonstrated the typical hemodynamic appearance of FNH known from CT studies. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract::Takayasu arteritis is a chronic inflammatory disease of unknown origin. The disease is characterized by transmural inflammation and fibrosis; the arterial lesions affect mainly the aorta and great vessels and sometimes involve the pulmonary arteries and visceral vessels. Despite efforts to create criteria for clinical...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:The state-of-art motion correction algorithm is inadequate for correcting motion artifacts in coronary arteries in cardiovascular computed tomography angiography (CCTA) for children with high heart rates, and even less effective for heart structures beyond coronary arteries. PURPOSE:This study aimed to eval...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000001035
更新日期:2020-09-01 00:00:00
abstract::Prenatal diagnosis of monoamnionicity is necessary for optimal care of a twin gestation. When the fetuses are discordant for a lethal anomaly, unequivocal confirmation is imperative. Ultrasound evaluation of our patient revealed a twin gestation discordant for anencephaly and with possible monoamnionicity. When sonogr...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199401000-00034
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:To characterize diffusion tensor imaging (DTI) tensor eigenvalues (λ1, λ2, λ3), fractional anisotropy, mean diffusivity, and radial diffusivity in healthy lumbar musculature. METHODS:Seventeen healthy subjects (10 men, 7 women; mean age, 28 ± 7 years) were scanned using a 3.0-T magnetic resonance imaging. A...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182772d66
更新日期:2013-01-01 00:00:00
abstract::Present popular computed tomography (CT) algorithms reconstruct an object from the ray measurements lying on a set of parallel planes. This paper presents an algorithm that can also utilize "cross-plane" rays (i.e., rays that cross through many planes) to reconstruct the object. In this reconstruction algorithm, the r...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197906000-00015
更新日期:1979-06-01 00:00:00
abstract::An enterogenous cyst of the craniocervical region producing anterior medullary compression is reported. The patient presented with quadriparesis with greater involvement of the upper limbs. Computed tomography showed a high attenuation intradural extramedullary mass located anteriorly. Magnetic resonance imaging demon...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199005000-00030
更新日期:1990-05-01 00:00:00