Stitching together RNA tertiary architectures.

Abstract:

:The powerful explanatory paradigm of molecular biology requiring form to co-evolve with function has again been proven successful when, over the recent two decades, a wealth of biological functions have been uncovered for RNA. Previously considered as a mere mediator of the genetic code, RNA is now acknowledged as a key player in a wide variety of cellular processes. Along with the discovery of novel biological functions of RNA molecules, a number of RNA three-dimensional structures have been solved which beautifully demonstrate the molecular adaptability which allows RNA to participate as a key player in these functions. A distinct repertoire of molecular motifs provides a basis for the assembly of complex RNA tertiary architectures.

journal_name

J Mol Biol

authors

Hermann T,Patel DJ

doi

10.1006/jmbi.1999.3312

keywords:

subject

Has Abstract

pub_date

1999-12-10 00:00:00

pages

829-49

issue

4

eissn

0022-2836

issn

1089-8638

pii

S0022-2836(99)93312-0

journal_volume

294

pub_type

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