Heme metabolism and lipid peroxidation in rat kidney hexachlorobenzene-induced porphyria: A compartmentalized study of biochemical pathogenic mechanisms.

abstract：BACKGROUND/AIMS:Acute kidney injury (AKI) is a serious complication of sepsis and has a high morbidity and mortality rate. Caspase-11 induces pyroptosis, a form of programmed cell death that plays a critical role in endotoxic shock, but its role in tubular epithelial cell death and whether it contributes to sepsis-asso...

journal_title：Kidney & blood pressure research

authors： Ye Z,Zhang L,Li R,Dong W,Liu S,Li Z,Liang H,Wang L,Shi W,Malik AB,Cheng KT,Liang X

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:We examined the factors associated with blood pressure variability in a multi-ethnicity prospective study in China to gain more evidence to guide the prevention and management of hypertension through risk factor intervention. METHODS:A total of 318 consecutive adult subjects aged 29-94 years with suspe...

journal_title：Kidney & blood pressure research

authors： Li W,Yu Y,Liang D,Jia EZ

更新日期：2017-01-01 00:00:00

abstract：:The present investigation examined the possible influence of urinary calcium excretion on the concentration of renal calbindin-D28k. Thiazide diuretics stimulate calcium transport across the epithelial cells of the distal tubule, which express calbindin-D28k in high concentrations. Calbindin-D28k is assumed to facilit...

journal_title：Kidney & blood pressure research

authors： Hemmingsen C,Staun M,Meibom K,Bang K,Olgaard K

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:Lowering dialysate temperature to increase intradialytic hemodynamic stability may interfere with the ultrafiltration-dependent intradialytic autonomic cardiovascular regulation. The present study aimed to investigate hemodynamic and autonomic responses depending on dialysate temperature and the presenc...

journal_title：Kidney & blood pressure research

authors： Zitt E,Neyer U,Meusburger E,Tiefenthaler M,Kotanko P,Mayer G,Rosenkranz AR

更新日期：2008-01-01 00:00:00

abstract：:In the pathogenesis of anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitis, T cell contribution is indicated by T cell-dependent ANCA production combined with the presence of T cells in inflammatory infiltrates. However, the exact pathogenic role of T cells in ANCA-associated vasculitis remains to be det...

journal_title：Kidney & blood pressure research

authors： Sanders JS,Stegeman CA,Kallenberg CG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:Hemodialysis (HD) patients often have inadequate nutrition, especially with respect to ascorbic acid (AA). It is reported that every HD session may cause a 50%- 75% decrease in plasma AA levels. Some studies have shown that supplementation of AA can change the outcome of chronic kidney disease-mineral b...

journal_title：Kidney & blood pressure research

authors： Ke G,Huang J,Zhu Y,Yang J,Zhang Y,Chen L,Hu J,Tao S,Hu Y,Yang D,Liu S

更新日期：2018-01-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate the influence of cycle exercise during hemodialysis (HD) on patients' physical proficiency, muscle strength, quality of life and selected laboratory parameters. PATIENTS AND METHODS:In a group of 29 (15 female, 14 male) HD patients (age 64.2 ± 13.1 years), 3 months of c...

journal_title：Kidney & blood pressure research

authors： Gołębiowski T,Kusztal M,Weyde W,Dziubek W,Woźniewski M,Madziarska K,Krajewska M,Letachowicz K,Strempska B,Klinger M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Endothelial-to-mesenchymal transition (EndMT) of glomerular endothelial cells (GEnCs) can induce albuminuria in diabetic nephropathy. Melatonin attenuates diabetic nephropathy, but its role and mechanism in EndMT of GEnCs in diabetic nephropathy remain unknown. METHODS:The effect of melatonin on EndMT ...

journal_title：Kidney & blood pressure research

authors： Liu F,Zhang S,Xu R,Gao S,Yin J

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:In the Chronic REnal Disease in Turkey-CREDIT Study, a large populationbased study on 10,748 adults, the prevalence of chronic kidney disease (CKD) and relationship between CKD and other cardiovascular risk factors had been studied. METHODS:This report presents the results of CREDIT study on the prevalence,...

journal_title：Kidney & blood pressure research

authors： Altun B,Süleymanlar G,Utaş C,Arınsoy T,Ateş K,Ecder T,Camsarı T,Serdengeçti K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Arterial hypertension is one of the leading factors aggravating the course of chronic kidney disease (CKD). It seems that the novel parameters used in the assessment of the blood pressure (BP) load (i.e. central blood pressure, nighttime blood pressure) may be more precise in predicting the cardiovascul...

journal_title：Kidney & blood pressure research

authors： Kuczera P,Kwiecień K,Adamczak M,Bączkowska T,Gozdowska J,Madziarska K,Augustyniak-Bartosik H,Klinger M,Durlik M,Ritz E,Wiecek A

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells (MSC) improve renal function and renovascular hypertension in the 2-kidney 1-clip model (2K-1C). While MSC play an immunomodulatory role, induce neoangiogenesis, and reduce fibrosis, they do not correct sodium loss by the contra-lateral kidney. OBJECTIVES:We investigated the tubular f...

journal_title：Kidney & blood pressure research

authors： Varela VA,Oliveira-Sales EB,Maquigussa E,Borges FT,Gattai PP,Novaes ADS,Shimoura CG,Campos RR,Boim MA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Hypertension in the elderly is commonly characterized by an elevation of pulse pressure. With regard to advanced arteriosclerosis and limited physical fitness, doubt was casted whether elderly patients still achieve relevant cardiovascular benefits by physical exercise. The present work examines the impact o...

journal_title：Kidney & blood pressure research

authors： Westhoff TH,Franke N,Schmidt S,Vallbracht-Israng K,Meissner R,Yildirim H,Schlattmann P,Zidek W,Dimeo F,van der Giet M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:Aortic arch calcification (AoAC) is frequently detected in maintenance hemodialysis (MHD) patients and is associated with cardiovascular and all-cause mortality. We investigated the factors associated with AoAC and analyzed the relationship between the factors including bone-derived biomarkers and AoAC....

journal_title：Kidney & blood pressure research

authors： Nitta K,Hanafusa N,Okazaki M,Komatsu M,Kawaguchi H,Tsuchiya K

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND METHODS:We investigated kidney function, renal endothelin-1 concentration, prepro-endothelin-1 mRNA as well as endothelin receptor A and B mRNA expression and receptor properties in normotensive Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) with intact renal nerves and 7 days after re...

journal_title：Kidney & blood pressure research

authors： Girchev RA,Bäcker A,Markova PP,Kramer HJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUNDS/AIMS:Vitamin C is an antioxidant and acts as a cofactor for several key enzymatic catalytic reactions in animals. Amphibians produce vitamin C in their kidneys, as opposed to mammals that produce vitamin C in their liver. Gulo serves as a crucial enzyme for vitamin C synthesis in mammals, but the characteri...

journal_title：Kidney & blood pressure research

authors： Xie Y,Liu Y,Zhao Y,Wang H,Liu Y,Wang H,Li M,Zhao H,Zhou Q,Lv X

更新日期：2016-01-01 00:00:00

abstract：:Backgroud/Aims: The aim of this study was to investigate the potential renoprotective effect of rapamycin on the autophagy of podocytes treated with the supernatant of mesangial cells cultured with aggregated IgA1 (aIgA1) from immunoglobulin A nephropathy (IgAN) patients. METHODS:Monomeric IgA1 (mIgA1) was isolated f...

journal_title：Kidney & blood pressure research

authors： Liang S,Jin J,Lin B,Gong J,Li Y,He Q

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIM:Calcifications of large arteries are frequent in chronic kidney disease (CKD) and may contribute to the high cardiovascular risk in this population. The aim of this study was to examine whether abdominal aortic calcification volume (AACV) was a predictor of the rate of decline in glomerular filtration ra...

journal_title：Kidney & blood pressure research

authors： Jansson H,Saeed A,Svensson MK,Finnved K,Hellström M,Guron G

更新日期：2019-01-01 00:00:00

abstract：:Angiotensin-(1-7), (Ang-(1-7)), a metabolite of Ang II and /or Ang I, was infused into the renal artery (i.r.a) of anesthetized dogs in order to demonstrate its possible direct renal action. The dose administered, 15 Ig/kg BW/min in isotonic saline (0.072 ml/kg BW/min) throughout the experiment, did not influence the ...

journal_title：Kidney & blood pressure research

authors： Heller J,Kramer HJ,Malý J,Cervenka L,Horácek V

更新日期：2000-01-01 00:00:00

abstract：:Heart failure and chronic kidney disease share a number of risk factors and pathophysiological pathways. Renal insufficiency is common in patients with chronic heart failure (CHF). The aim of the study was to assess whether neutrophil gelatinase-associated lipocalin (NGAL) could represent a novel, sensitive marker of ...

journal_title：Kidney & blood pressure research

authors： Poniatowski B,Malyszko J,Bachorzewska-Gajewska H,Malyszko JS,Dobrzycki S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Analysis of gene expression in renal tissue is considered to be a diagnostic tool predicting the clinical course of glomerulonephritis. The present study quantified the relative transcript levels of VEGF, CTGF and HIF-1α in renal tissue to establish their relationship with some clinical variables in pat...

journal_title：Kidney & blood pressure research

authors： Donderski R,Szczepanek J,Domagalski K,Tretyn A,Korenkiewicz J,Marszałek A,Szymański A,Wolski Z,Odrowąż-Sypniewska G,Manitius J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Uremic toxins have been shown to promote glomerular hypertrophy. The present study was performed to elucidate the relation between uremic toxins and tubulointerstitial changes. METHODS:Sixty male Sprague-Dawley rats underwent 2/3 nephrectomy (Nx; n = 30) and 4/5 Nx (n = 30). Experiments were initiated 2 wee...

journal_title：Kidney & blood pressure research

authors： Okada K,Matsumoto K,Takahashi S

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Kidney function is critical for homocysteine (Hcy) clearance, and plasma Hcy levels are frequently increased in patients with renal failure. Microalbuminuria (MAU) is an important marker of early renal damage caused by hypertension. At present, there is insufficient evidence on the relationship between ...

journal_title：Kidney & blood pressure research

authors： Kuang ZM,Wang Y,Feng SJ,Jiang L,Cheng WL

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Renal dysfunction is a frequent complication in patients suffering from β-thalassemia major (β-TM). The aim of this study was to analyze the renal function and urine metabolomic profile of β-TM patients undergoing transfusions and deferasirox (DFX) therapy, in order to better characterize and shed light on...

journal_title：Kidney & blood pressure research

authors： Capolongo G,Zacchia M,Beneduci A,Costantini S,Cinque P,Spasiano A,De Luca G,Di Pietro ME,Ricchi P,Trepiccione F,Capasso G,Filosa A

更新日期：2020-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the renoprotective effect of angiotensin-converting enzyme inhibitors (ACEIs) following 5/6 renal mass reduction is due in part to the potentiation of kinins. Three groups of rats with 5/6 renal mass reduction were studied during the 14 weeks following surgery. One grou...

journal_title：Kidney & blood pressure research

authors： MacLaughlin M,Monserrat AJ,Muller A,Matoso M,Amorena C

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Metabolic acidosis may be diagnosed as chronic (cMA) if it persists for at least 5 days, although an exact definition has not been provided by any guidelines yet. The most common cause is CKD; numerous less-known diseases can also account for cMA. SUMMARY:In recent years, CKD-associated cMA has been propose...

journal_title：Kidney & blood pressure research

authors： Patschan D,Patschan S,Ritter O

更新日期：2020-01-01 00:00:00

abstract：AIM:To assess the influence on blood pressure in schoolchildren, of elevated sodium (Na(+)) and nitrate (NO(-)(3)) levels in the drinking water. METHODS:The blood pressure was recorded in three groups of age- and weight-matched schoolchildren (fourth and fifth graders) ingesting differing Na(+) and NO(-)(3) concentrat...

journal_title：Kidney & blood pressure research

authors： Pomeranz A,Korzets Z,Vanunu D,Krystal H,Wolach B

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Cardiovascular disease is one of the main causes of morbidity and mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Autonomic dysfunction is associated with an increased risk for all cardiovascular events in the general population and can be evaluated with heart rate variabil...

journal_title：Kidney & blood pressure research

authors： Lai S,Mangiulli M,Perrotta AM,Di Lazzaro Giraldi G,Testorio M,Rosato E,Cianci R,Gigante A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Lipopolysaccharides (LPS) binding to Toll-like receptor 4 (TLR4) activate NADPH oxidase gp91 subunit-mediated inflammation and oxidative damage. Recognizing the high binding affinity of sialic acid (SA) with LPS, we further explored the preventive potential of SA pretreatment on LPS-evoked acute renal f...

journal_title：Kidney & blood pressure research

authors： Hsu SP,Chen CC,Chien CT

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:The main purpose of the present study was to determine the effect of peritoneal charge barrier dysfunction on hypoalbuminemia during CAPD. METHODS:We measured the association of dialysis dose, peritoneal equilibration test (PET) results (ratio of dialysate and plasma creatinine), and peritoneal charge ...

journal_title：Kidney & blood pressure research

authors： Yu GQ,Chen J,Li JX

更新日期：2013-01-01 00:00:00

abstract：:Renal proximal tubular Na/phosphate cotransport is the key target in the control of renal phosphate handling. Using molecular tools for the type II Na/phosphate cotransporter, it could be documented that altered brush border membrane phosphate transport reflects a state of altered brush border expression of the specif...

journal_title：Kidney & blood pressure research

authors： Murer H,Lötscher M,Kaissling B,Biber J

更新日期：1996-01-01 00:00:00