Contribution of apolipoprotein(a) size, pentanucleotide TTTTA repeat and C/T(+93) polymorphisms of the apo(a) gene to regulation of lipoprotein(a) plasma levels in a population of young European Caucasians.

abstract：:Blood cells express a cell membrane protein, termed homologous restriction factor 20 (HRF20) and identical to CD59, that can inhibit complement C5b-9 insertion into their membranes. In this report, we investigated by immunohistochemistry whether CD59 was present on cells in human atherosclerotic lesions since membrano...

journal_title：Atherosclerosis

authors： Seifert PS,Roth I,Schmiedt W,Oelert H,Okada N,Okada H,Bhakdi S

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:We investigated whether early atherosclerosis before calcified plaque appeared as assessed by carotid intima-media thickness (IMT) was associated with levels of the major carotenoids, and assessed the associations among these serum carotenoids, carotid IMT, and arterial stiffness. METHODS:The case-control st...

journal_title：Atherosclerosis

authors： Zou Z,Xu X,Huang Y,Xiao X,Ma L,Sun T,Dong P,Wang X,Lin X

更新日期：2011-12-01 00:00:00

abstract：:As a model for the formation of beta-very low density lipoproteins (VLDL) and small, dense LDL by the intraplasma metabolic activities in vivo, lipoproteins in fresh plasma were interacted in vitro with endogenous lecithin:cholesterol acyltransferase (LCAT) and cholesterylester transfer proteins (CETP) and subsequentl...

journal_title：Atherosclerosis

authors： Chung BH,Segrest JP,Franklin F

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:In chronic kidney disease (CKD), high FGF23 concentrations are associated with left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of FGF23 with left ventricular mass (LVM) and LVH in the general population and the influence of CKD remains uncertain. METHODS:C-terminal pla...

journal_title：Atherosclerosis

authors： Jovanovich A,Ix JH,Gottdiener J,McFann K,Katz R,Kestenbaum B,de Boer IH,Sarnak M,Shlipak MG,Mukamal KJ,Siscovick D,Chonchol M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND AIMS:High concentrations of low density lipoprotein (LDL) triglycerides have been associated with prevalent angiographic coronary artery disease. The present analysis was designed to investigate the association of LDL triglycerides with cardiovascular mortality and to explore possible mechanisms that may...

journal_title：Atherosclerosis

authors： Silbernagel G,Scharnagl H,Kleber ME,Delgado G,Stojakovic T,Laaksonen R,Erdmann J,Rankinen T,Bouchard C,Landmesser U,Schunkert H,März W,Grammer TB

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Exercise training (ET) helps treat atherosclerosis. However, many patients stop regular ET for various reasons. The effect of detraining on atherosclerosis is not well studied. We examined the effects of ET vs. short-term detraining on atheromatous matrix-metalloproteinase (MMP) activity in preexist...

journal_title：Atherosclerosis

authors： Kim J,Jang HJ,Schellingerhout D,Kang JW,Choi S,Oh H,Kim EJ,Lee SK,Lee JS,Kwon IC,Kim K,Koh YJ,Ryu WS,Kim DE

更新日期：2020-04-01 00:00:00

abstract：:Atherosclerotic calcification may weaken the aorta wall and thereby lead to rupture of the vessel. The mechanism whereby aortas undergo calcification remains unclear. Previous reports in this laboratory showed that, after 2 months of cholesterol-supplemental feeding, an increase in calcifiability of membrane vesicles ...

journal_title：Atherosclerosis

authors： Hsu HH,Camacho NC,Tawfik O,Sun F

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND & AIMS:Dysbiosis of the gut microbiota is associated with increased levels of circulating lipopolysaccharide (LPS) and subsequent activation of systemic inflammation. Diet is an important modulator of the gut microbiome. We aimed to investigate whether circulating markers of gut-related inflammation, LPS bin...

journal_title：Atherosclerosis

authors： Awoyemi A,Trøseid M,Arnesen H,Solheim S,Seljeflot I

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that renin-angiotensin system (RAS) may play a major role in the actively regulated fibrocalcific process in aortic valve stenosis (AS), but the gene expression or function of (pro)renin receptor ((P)RR), prorenin and renin or angiotensin converting enzyme 2(ACE2)/angiotensin-(1-...

journal_title：Atherosclerosis

authors： Peltonen T,Näpänkangas J,Ohtonen P,Aro J,Peltonen J,Soini Y,Juvonen T,Satta J,Ruskoaho H,Taskinen P

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Adherence to a Mediterranean-style diet (MeDi) may protect against clinical vascular events by reducing atherosclerosis, but data is limited. This is the first observational study of the association between MeDi adherence and carotid plaque thickness and area. METHODS:The study included 1374 participants of ...

journal_title：Atherosclerosis

authors： Gardener H,Wright CB,Cabral D,Scarmeas N,Gu Y,Cheung K,Elkind MS,Sacco RL,Rundek T

更新日期：2014-06-01 00:00:00

abstract：:Inflammatory cytokine synthesis by monocyte-macrophages in the developing plaque represents an important amplification point in atherosclerotic disease progression. Here we have investigated whether the state of monocyte-macrophage differentiation can influence TNF alpha synthesis in response to scavenged modified low...

journal_title：Atherosclerosis

authors： Smythe CD,Skinner VO,Bruckdorfer KR,Haskard DO,Landis RC

更新日期：2003-10-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and the incidence of which is rising rapidly due to the increasing epidemic of obesity in both adults and children. The initial accumulation of fat followed by subsequent inflammation is central to the development of liver...

journal_title：Atherosclerosis

authors： Than NN,Newsome PN

更新日期：2015-03-01 00:00:00

abstract：:Homocysteine may promote atherogenesis and thrombogenesis by enhancing leukocyte-endothelium interactions. We explored this hypothesis in an acute hyperhomocysteinemia rat model, which was created by a continuous venous homocysteine infusion (4 ml/h/kg body weight) with 2.5 and 10 mg/ml D,L-homocysteine upto 90 min. V...

journal_title：Atherosclerosis

authors： Fu WY,Dudman NP,Perry MA,Wang XL

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Vascular calcification is an active deposition process of calcium phosphate which resembles bone formation and is highly regulated by osteoblast-like cells. Existing studies demonstrate that advanced glycation end-products (AGEs) may play a pathogenic role in the vascular calcification process. However, their...

journal_title：Atherosclerosis

authors： Wang Z,Jiang Y,Liu N,Ren L,Zhu Y,An Y,Chen D

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:Receptor-associated protein (RAP) was initially described as a regulator of low density lipoprotein receptor-related protein 1 (LRP1), but is now known to regulate many proteins. Since the direct effects of RAP on vascular pathologies have not been studied, this study determined whether RAP deficiency influen...

journal_title：Atherosclerosis

authors： Wang S,Subramanian V,Lu H,Howatt DA,Moorleghen JJ,Charnigo R,Cassis LA,Daugherty A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND/AIM:In type 2 diabetes and other insulin-resistant conditions, postprandial hypertriglyceridaemia is an important metabolic perturbation. To further elucidate alterations in the clearance of triglyceride-rich lipoproteins in type 2 diabetes we focused on the nutritional regulation of adipose tissue lipoprote...

journal_title：Atherosclerosis

authors： Eriksson JW,Burén J,Svensson M,Olivecrona T,Olivecrona G

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:To explore the therapeutic potential of fibrates to attenuate premature atherosclerosis and cardiovascular disease in the atherogenic dyslipidemias typical of Type II diabetes, Metabolic Syndrome, and the Type IIB (mixed) lipid phenotype; such dyslipidemias frequently feature peripheral insulinoresistance. ...

journal_title：Atherosclerosis

authors： Chapman MJ

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Circulating levels of adhesion molecules increase in various inflammation-related diseases, such as atherosclerosis. However, data about factors influencing their concentrations in physiological conditions are scarce. METHODS:We have studied the determinants of serum levels of intercellular adhesion molecul...

journal_title：Atherosclerosis

authors： Ponthieux A,Herbeth B,Droesch S,Haddy N,Lambert D,Visvikis S

更新日期：2004-02-01 00:00:00

abstract：:Intermittent claudication (IC) is defined by leg muscle pain, cramping and fatigue brought on by ambulation/exercise; relieved on rest; and caused by inadequate blood supply and is the primary symptom of peripheral arterial disease (PAD). PAD has a detrimental effect on the quality of life. PAD is a debilitating ather...

journal_title：Atherosclerosis

authors： Meru AV,Mittra S,Thyagarajan B,Chugh A

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:Postprandial hyperlipemia has been shown to impair endothelial function and contribute to the development of atherosclerosis. We investigated the association between postprandial lipid profiles and endothelial function, and we examined the effects of ezetimibe on postprandial hyperlipemia and lipemia-induced ...

journal_title：Atherosclerosis

authors： Yunoki K,Nakamura K,Miyoshi T,Enko K,Kohno K,Morita H,Kusano KF,Ito H

更新日期：2011-08-01 00:00:00

abstract：:Connective tissue growth factor (CTGF) is expressed in atherosclerotic plaques. It is generally recognized that CTGF contributes to atherosclerosis by stimulating vascular smooth muscle cell (VSMC) proliferation and extracellular matrix production during the development of atherosclerosis. Recent studies indicate that...

journal_title：Atherosclerosis

authors： Game BA,He L,Jarido V,Nareika A,Jaffa AA,Lopes-Virella MF,Huang Y

更新日期：2007-05-01 00:00:00

abstract：:We report on the results of a large autopsy study focusing upon the hypothesis that deletion of the Alu insert in the angiotensin converting enzyme (ACE) gene is associated with: (a) greater prevalence or extent of atherosclerosis in the aorta and coronary arteries; and (b) microscopic qualities of established atheros...

journal_title：Atherosclerosis

authors： Scheer WD,Boudreau DA,Hixson JE,McGill HC,Newman WP 3rd,Tracy RE,Zieske AW,Strong JP

更新日期：2005-02-01 00:00:00

abstract：:The effect of short-term dietary restriction on plasma cholesterol and cholesterol balance was examined in young While Carneau pigeons. Dietary restriction of 1 month increased plasma cholesterol significantly and subsequently decreased to initial levels at 3 months. The fecal excretion of neutral sterols was signific...

journal_title：Atherosclerosis

authors： Subbiah MT,Connelly PW

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Estrogen therapy that is started at the time of menopause seems to protect against the development of atherosclerosis and cardiovascular diseases, in contrast to the initial increased cardiovascular risk when hormone therapy is initiated in older women. With increased aging and degree of atherosclerosis, the...

journal_title：Atherosclerosis

authors： Naessen T,Rodriguez-Macias K

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:The response to retention hypothesis of atherogenesis proposes that atherosclerosis is initiated via the retention of atherogenic lipoproteins by vascular proteoglycans. Co-localization studies suggest that of all the vascular proteoglycans, biglycan is the one most closely co-localized with LDL. The goal of ...

journal_title：Atherosclerosis

authors： Thompson JC,Tang T,Wilson PG,Yoder MH,Tannock LR

更新日期：2014-07-01 00:00:00

abstract：:Oxidation of low density lipoprotein (LDL) leads to more rapid uptake by arterial wall macrophages and foam cell formation. Inhibiting LDL oxidation may impede these processes and offers a new mechanism to retard atherogenesis. The 21-aminosteroids, derived from methylprednisolone, are potent inhibitors of free radica...

journal_title：Atherosclerosis

authors： Fisher M,Levine PH,Doyle EM,Arpano MM,Hoogasian JJ

更新日期：1991-10-01 00:00:00

abstract：AIMS:To assess efficacy and safety of HMG-CoA reductase inhibitor (statin) treatment in children and adolescents with heterozygous familial hypercholesterolaemia. METHODS:MEDLINE, EMBASE, COCHRANE and Current Controlled Trials databases were searched. Study design, efficacy, and safety outcome-measures were extracted....

journal_title：Atherosclerosis

authors： Arambepola C,Farmer AJ,Perera R,Neil HA

更新日期：2007-12-01 00:00:00

abstract：:Young pigs with hypertension of 10 weeks duration, resulting from cellophane perinephritis, were injected with 125I-labelled low-density lipoprotein ([125I]LDL) before being killed 24 h or 48 h later. Intimal thickening and increased acid mucopolysaccharide were demonstrated in the aortas and major arteries of the hyp...

journal_title：Atherosclerosis

authors： Sharpe DN,Scott PJ,Flint MH,Donald J

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Both elevated serum uric acid (SUA) and peripheral endothelial dysfunction (PED) are associated independently with cardiovascular disease (CVD). However, the association between SUA and PED is yet to be established. We hypothesized that high normal range of SUA is associated with PED. METHODS:We pe...

journal_title：Atherosclerosis

authors： Taher R,Sara JD,Prasad M,Kolluri N,Toya T,Lerman LO,Lerman A

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Only one study has examined endothelial function in subjects with acute ischemic stroke and no study has yet assessed arterial stiffness and reactive hyperemia peripheral arterial tonometry (RH-PAT) in ischemic stroke and its clinical subtypes. Our study aimed to evaluate arterial stiffness and endo...

journal_title：Atherosclerosis

authors： Tuttolomondo A,Casuccio A,Della Corte V,Maida C,Pecoraro R,Di Raimondo D,Vassallo V,Simonetta I,Arnao V,Pinto A

更新日期：2017-01-01 00:00:00