Structure, assembly, and dynamics of actin filaments in situ and in vitro.

Abstract:

:Actin, though highly conserved, exhibits a myriad of diverse functions, most of which ultimately depend on its intrinsic ability to rapidly assemble and disassemble filamentous structures. Many organisms synthesize multiple actin isoforms even within the same cell. Tissue-specific expression patterns and tight developmental regulation as well as a high conservation across species emphasize the functional importance of isoforms. The detailed knowledge of the structure, assembly, and dynamic behavior of actin provides important pieces in solving the puzzle of how the different isoforms can be so versatile despite their extremely high sequence identity.

journal_name

Microsc Res Tech

authors

Schoenenberger CA,Steinmetz MO,Stoffler D,Mandinova A,Aebi U

doi

10.1002/(SICI)1097-0029(19991001)47:1<38::AID-JEMT

keywords:

subject

Has Abstract

pub_date

1999-10-01 00:00:00

pages

38-50

issue

1

eissn

1059-910X

issn

1097-0029

pii

10.1002/(SICI)1097-0029(19991001)47:1<38::AID-JEMT

journal_volume

47

pub_type

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