Abstract:
:Actin, though highly conserved, exhibits a myriad of diverse functions, most of which ultimately depend on its intrinsic ability to rapidly assemble and disassemble filamentous structures. Many organisms synthesize multiple actin isoforms even within the same cell. Tissue-specific expression patterns and tight developmental regulation as well as a high conservation across species emphasize the functional importance of isoforms. The detailed knowledge of the structure, assembly, and dynamic behavior of actin provides important pieces in solving the puzzle of how the different isoforms can be so versatile despite their extremely high sequence identity.
journal_name
Microsc Res Techjournal_title
Microscopy research and techniqueauthors
Schoenenberger CA,Steinmetz MO,Stoffler D,Mandinova A,Aebi Udoi
10.1002/(SICI)1097-0029(19991001)47:1<38::AID-JEMTkeywords:
subject
Has Abstractpub_date
1999-10-01 00:00:00pages
38-50issue
1eissn
1059-910Xissn
1097-0029pii
10.1002/(SICI)1097-0029(19991001)47:1<38::AID-JEMTjournal_volume
47pub_type
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