Progression of cancer.

abstract：:Epilepsy is a chronic neurologic disorder which often induces numerous adverse long-term neurologic effects, such as behavioral and cognitive deficits, increased predisposition to additional seizures, and cell injury or death. Cognitive dysfunction, depression, anxiety and sleep disorders are some of the highly preval...

journal_title：Medical hypotheses

authors： Vimala PV,Bhutada PS,Patel FR

更新日期：2014-01-01 00:00:00

abstract：:Multiple reports show the efficacious usage of ECT for catatonia in individuals with autism. There are also a few reports showing that ECT improves self-injury in people with and without autism. In this hypothesis, self-injury in autism and other developmental disorders may be an alternate sign of catatonia, and as su...

journal_title：Medical hypotheses

authors： Wachtel LE,Dhossche DM

更新日期：2010-07-01 00:00:00

abstract：:The affected individual of hair loss demands help, because hair is viewed as a sign of youth and good health. Nowadays treatment of alopecia includes drug therapy and hair transplantation. Some drugs may promote hair growth, at least temporarily, but the treatment is effective only in milder alopecia, instead of exten...

journal_title：Medical hypotheses

authors： Zhao J,Liu LQ,Wang YJ,Yang W,Geng WX,Wei J,Li LW,Chen FL

更新日期：2008-01-01 00:00:00

abstract：:Dietary chromium supplementation for the treatment of diabetes remains controversial. The prevailing view that chromium supplementation for glucose regulation is unjustified has been based upon prior studies showing mixed, modest-sized effects in patients with type 2 diabetes (T2DM). Based on chromium's potential to i...

journal_title：Medical hypotheses

authors： Brownley KA,Boettiger CA,Young L,Cefalu WT

更新日期：2015-07-01 00:00:00

abstract：:Acid hydrolysis of components from the diet in the stomach require the presence of an acid and a hydrolysing agent. The acid involved is hydrochloric acid. The present mechanism of hydrochloric acid production in the stomach is demonstrated to be incompatible with measured intracellular or intercellular concentrations...

journal_title：Medical hypotheses

authors： Robertson DS

更新日期：2005-01-01 00:00:00

abstract：:Essential hypertension is a heterogeneous multifactorial syndrome associated with a high cardiovascular risk. A multiple choice of antihypertensive drugs is available; however, a high individual variability to the antihypertensive therapy is still responsible for a modest reduction of the CV risk and not satisfactory ...

journal_title：Medical hypotheses

authors： Ferrari P,Ferrandi M,Valentini G,Manunta P,Bianchi G

更新日期：2007-01-01 00:00:00

abstract：:We have observed a distinct difference in the alpha-fetoprotein production of Sprague-Dawley rats and Swiss white mice. When both animals are fed a 1% D/L-ethionine diet, only the rat responds with increased levels of hepatic alpha-fetoprotein synthesis as shown by radioimmunoassay studies. Also, hybridization studies...

journal_title：Medical hypotheses

authors： Payette R,Hancock RL

更新日期：1982-10-01 00:00:00

abstract：:Dupuytren's disease is a pathological condition of the palmar fascia characterized by the formation of contractile disease cords that result in permanent finger contracture. This condition is believed to progress from a myofibroblast-rich nodule in the early clinical stages of the disease to a contractile disease cord...

journal_title：Medical hypotheses

authors： Vi L,Gan BS,O'Gorman DB

更新日期：2010-03-01 00:00:00

abstract：:This thesis explores the activation of chemicals in metabolic systems from the viewpoint that this activation is under the control of elements of the space-sea in which the chemicals are immersed. Themselves inert, the chemicals are theorised to exploit a force or action issuing from space (fluctuation) and characteri...

journal_title：Medical hypotheses

authors： Reid BL,Bourke C

更新日期：2001-07-01 00:00:00

abstract：:Information about the etiology of pressure sores has been contradictory and is inconsistent with the idea that pressure sore formation is due extensively to depriving a tissue region of blood. Based on these observations and on studies done in the cooperating laboratories, an hypothesis has been formulated that integr...

journal_title：Medical hypotheses

authors： Krouskop TA

更新日期：1983-06-01 00:00:00

abstract：:As human society is mainly cooperative, it is not clear how antisocial personality disorder (APD) persists. The current explanation is that sociopaths are cheaters who maximize their fitness by taking advantages from others. Although this argument is valid, we show here that society also benefits from APD. We propose ...

journal_title：Medical hypotheses

authors： Miric D,Hallet-Mathieu AM,Amar G

更新日期：2005-01-01 00:00:00

abstract：:In Burkitt's lymphoma, dental structures may provide the route for Epstein-Barr virus (EBV) in saliva to penetrate the jaws, thereby promoting tumor formation. In children, EBV could enter tooth sockets exposed following deciduous tooth loss and thereby contact jaw marrow lymphocytes stimulating neoplastic transformat...

journal_title：Medical hypotheses

authors： Lorber M

更新日期：1983-12-01 00:00:00

abstract：:Seroepidemiological, clinical and molecular findings suggest that the acquired immune deficiency syndrome virus human immunodeficiency virus-1 was introduced into the human species at the time (late 1950s) and in the geographic area (Zaire) in which millions of Africans were vaccinated with attenuated poliomyelitis vi...

journal_title：Medical hypotheses

authors： Reinhardt V,Roberts A

更新日期：1997-05-01 00:00:00

abstract：:It has been suggested that dopamine may play an important role in human evolution and adaptive behaviors. Recent studies have revealed an association between the dopamine system and social support among healthy individuals. However, the underlying mechanism remains unclear. In the present study, we propose a dopamine ...

journal_title：Medical hypotheses

authors： Lin SH,Chen PS,Yeh TL,Yang YK

更新日期：2011-11-01 00:00:00

abstract：:Cancer is a tissue that requires a genetic program, possibly involving hundreds of genes, as indicated by studies of differential gene expression performed with microarrays in various types of cancer. Cancer is thus a biological process of considerable precision as described by Schrödinger's equation, and it is not si...

journal_title：Medical hypotheses

authors： Garcia-Garcia A

更新日期：2009-04-01 00:00:00

abstract：:The existence of homosexuality in humans poses a problem for evolutionary theory. Exclusive male homosexuality has a catastrophic effect on reproduction and yet inherited factors appear to contribute to it. Previous attempts to resolve this conundrum are inconsistent with aspects of evolutionary theory. Additional lim...

journal_title：Medical hypotheses

authors： Dewar CS

更新日期：2003-02-01 00:00:00

abstract：:For many years there was a general belief that the enzyme renin, having been secreted into the circulation by the kidney in response to appropriate stimuli, initially generates the inactive decapeptide angiotensin I in the bloodstream. This is then converted to the biologically active octapeptide angiotensin II by ang...

journal_title：Medical hypotheses

authors： Duckworth AJ,Goodship AE,Kendall HJ,Osborn EC

更新日期：2001-04-01 00:00:00

abstract：:Radiotherapy (RT) has been established to improve both local control as well as overall survival rates in breast cancer. However, RT especially in left-sided breast cancer also irradiates a portion of the heart. Radiation associated toxicity to the heart assumes significance because of improval in survival of breast c...

journal_title：Medical hypotheses

authors： Gupta D,Shukla P,Munshi A,Aggarwal JP

更新日期：2012-03-01 00:00:00

abstract：:The constant level of various proteins including albumin and cellular components in intravascular pool in vivo is strictly controlled by an unknown homeostatic mechanism, although there are fluctuations seen in pathologic conditions. Because the majority of the IgG in the serum is regarded as self-reactive natural aut...

journal_title：Medical hypotheses

authors： Lee KY,Lee JS

更新日期：2006-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common primary tumor of liver and its incidence continues to increase worldwide. HCC is a disease with multifactorial causes and genetic variability has been discussed as a risk factor for its development. Liver is a hormone-sensitive organ and therefore is influenced by gona...

journal_title：Medical hypotheses

authors： Baldissera VD,Alves AF,Almeida S,Porawski M,Giovenardi M

更新日期：2016-01-01 00:00:00

abstract：:A neural network approach to modeling the development of personality traits through social learning is presented. From the more general model the special case of a network mapping four situation dimensions (input neurons) into seven dimensional personality traits (output neurons) is described. This network is allowed ...

journal_title：Medical hypotheses

authors： Gonzalez-Heydrich J

更新日期：1993-08-01 00:00:00

abstract：:This study investigated whether or not the anesthetic effect of ketamine in rats is dependent on adrenal gland hormones. The study was performed on two main rat groups, intact and adrenalectomized. Rat were divided into subgroups and given appropriate doses of ketamine, metyrapone or metyrosine. Durations of anesthesi...

journal_title：Medical hypotheses

authors： Aksoy M,Ince I,Ahiskalioglu A,Dostbil A,Celik M,Turan MI,Cetin N,Suleyman B,Alp HH,Suleyman H

更新日期：2014-07-01 00:00:00

abstract：:A role for lipopolysaccharides (endotoxins, LPS) in 7 the pathogenesis of Reye's syndrome (RS) has previously been suggested. Impairment of hepatic LPS clearance can lead to systemic endotoxemia as previous studies by this and other laboratories have suggested for several hepatic disorders including RS. Systemic LPS m...

journal_title：Medical hypotheses

authors： Treon SP,Broitman SA

更新日期：1992-11-01 00:00:00

abstract：:The current epidemic of obesity has developed at a rate that cannot be attributed to genetic drift. Attempts to treat obesity using diet and activity have been largely disappointing. Genes are fixed at conception, but genetic expression is known to be influenced by nutriture during the stages of growth and development...

journal_title：Medical hypotheses

authors： Blonz ER

更新日期：2006-01-01 00:00:00

abstract：:A major factor relating to the oversight of neurological dysfunction and seizures caused by magnesium (Mg++) depletion, involves the buffer functions of the skeletal system orchestrated primarily by the parathyroid. A Mg++ depleted subject may appear relatively asymptomatic until a short period after homeostatic respo...

journal_title：Medical hypotheses

authors： Langley WF,Mann DJ

更新日期：1991-01-01 00:00:00

abstract：:Cell-mediated immunity is generally regarded as the essential factor in recovery from measles infection. In other viral infections humoral immunity has been considered a critical factor when antibody titres were correlated with outcome or when serum therapy proved protective. A review of available studies of severe-to...

journal_title：Medical hypotheses

authors： Aaby P,Bukh J,Hoff G,Lisse IM,Smits AJ

更新日期：1987-07-01 00:00:00

abstract：:In mathematics and physics, chaos theory deals with the behavior of certain nonlinear dynamical systems that under certain conditions exhibit a phenomenon known as chaos, which is characterised by a sensitivity to initial conditions. Mathematicians paradoxically call such states of order chaos and distinguish them fro...

journal_title：Medical hypotheses

authors： Zifan A,Gharibzadeh S

更新日期：2006-01-01 00:00:00

abstract：:A new hypothesis concerning the association of low levels of steroid hormones and hypercholesterolemia is proposed. This study presents data that concurrent restoration to youthful levels of multiple normally found steroid hormones is able to normalize or improve serum total cholesterol (TC). We evaluated 20 patients ...

journal_title：Medical hypotheses

authors： Dzugan SA,Arnold Smith R

更新日期：2002-12-01 00:00:00

abstract：:The molecular similarity between certain human antigenic determinants with those of HIV has been already described. In this matter, we have previously demonstrated, by a chromatographic method, the cross reactivity of human serum albumin with HIV gp 120. The hypothesis that this similarity could be one of the reasons ...

journal_title：Medical hypotheses

authors： Berger G

更新日期：2002-05-01 00:00:00

abstract：:The efficiency of anti-tumour drug strongly depends on its dose. Higher drug doses and exposure times usually result in better treatment. It is why the implementation of high-dose treatment is always attractive. However, most of the drug delivery techniques meet essential limitations. In isolated regional perfusion a ...

journal_title：Medical hypotheses

authors： Rukhlenko OS,Guria GT,Vorobiev AI

更新日期：2017-07-01 00:00:00