Abstract:
:We have developed a cell-free system that can trigger the nuclei purified from mouse liver and suspension-cultured carrot cells to undergo apoptosis as defined by the formation of apoptotic bodies and nucleosomal DNA fragments. The effects of different divalent cations and cycloheximide on DNA cleavage in this system were assessed. The fact that nuclei of plant cells can be induced to undergo apoptosis in a cell-free animal system suggests that animals and plants share a common signal transduction pathway triggering in the initiation stage of apoptosis.
journal_name
Cell Resjournal_title
Cell researchauthors
Jiang ZF,Zhu S,Sun YL,Zhai ZHdoi
10.1038/sj.cr.7290008keywords:
subject
Has Abstractpub_date
1999-06-01 00:00:00pages
79-90issue
2eissn
1001-0602issn
1748-7838journal_volume
9pub_type
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