Abstract:
:The liver immune function is associated with specific lymphocyte population transiently marginated in the liver sinusoids. These cells are of blood origin, however they are phenotypically and functionally different from peripheral blood lymphocytes. The question arises whether tumor proliferating in the liver can modify cell recruitment and function of marginating sinusoidal lymphocytes. Studies were performed in Wistar rats. Livers of normal and colon cancer (induced by i.v. injection of CC531 cells) metastases bearing rats were perfused for sinusoidal lymphocyte isolation. Our studies showed no difference between the number of lymphocytes retained in sinusoids of tumor bearing and normal rats. T lymphocyte subsets remained in similar proportions in liver with colorectal metastases as in normal rats. Long lasting presence of tumor in the liver was accompanied by decreased cytotoxic activity of liver sinusoidal lymphocytes, whereas it had no influence on cytotoxicity of peripheral blood lymphocytes. Repopulation of tumor liver with peripheral blood cells restored cytotoxic activity of sinusoidal lymphocytes.
journal_name
Ann Transplantjournal_title
Annals of transplantationauthors
Durowicz S,Dłuzniewska J,Laszuk D,Olszewski WL,Lukomska Bkeywords:
subject
Has Abstractpub_date
1998-01-01 00:00:00pages
32-6issue
4eissn
1425-9524issn
2329-0358journal_volume
3pub_type
杂志文章abstract::BACKGROUND The number of pregnancies after liver transplantation (LT) is increasing; however, the safety and incidence of complications associated with these pregnancies are still unclear. In this report, we retrospectively assessed the influences and problems associated with post-transplant pregnancy on allografts, r...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.921193
更新日期:2020-06-09 00:00:00
abstract:BACKGROUND:Lung transplant recipients are at great risk for developing various infectious complications. These infections portend a significant morbidity and mortality throughout their lifetime following transplantation. At times, cutaneous manifestations are the only clues to systemic infection. CASE REPORT:A 62 year...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.883846
更新日期:2013-03-14 00:00:00
abstract:OBJECTIVE:Extensive stricture of ureter still poses a difficult challenge for urologic surgons, especially when its middle part is affected. We present a reconstructive method of long ureteral strictures with use of xenogenic collagen membranes as a scaffolding to promote new tissue growth in the area of extensive uret...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::BACKGROUND Left ventricular assist devices (LVAD) are used to treat heart failure. Preoperative prediction of RV function after LVAD implantation is crucial. Correlations were found between preoperative echo and RV function after LVAD implantation. MATERIAL AND METHODS We retrospectively reviewed 23 male patients (8 i...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.899054
更新日期:2016-08-11 00:00:00
abstract:OBJECTIVES:The goal of this study was to examine the impact of various immunosuppressive regimens on an early NK cell recovery following haematopoietic cell transplantation (alloHCT). METHODS:The number of peripheral blood NK cells was analysed with the use of flow cytometry on day +30 (+/-2) after alloHCT from an HLA...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Applications of allogenic amnion grafts range from wound dressing of severe burns, dermabrasions and lower extremity ulcer treatments to plastic surgery, laryngology and ophthalmology. The aim of the present study was to elaborate the method of processing, preservation and sterilization of human amnion allografts prep...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:The impact of treated preoperative bacterial infections on the outcome of living-donor liver transplantation (LDLT) is not well defined. The aim of this study was to determine the frequency of pre-transplant bacterial infections within one month before LDLT and their impact on the post-transplant morbidity a...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.892095
更新日期:2014-12-23 00:00:00
abstract:UNLABELLED:In spite of progress in biotechnology, isolation of porcine pancreatic islets remains a difficult task with unpredictable results. One reason could be the lack of knowledge as to the expression of extracellular matrix proteins in porcine exocrine and endocrine tissues, particularly in "islet capsules". Such ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::BACKGROUND Correction of hypovitaminosis D is simple, but it is unclear whether it is associated with an accelerated decline of renal allograft function in pediatric renal transplantation patients. This retrospective single center cohort study aimed at analyzing the effect of vitamin D and covariates on the slope of 1...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2018-04-17 00:00:00
abstract::Transplantation of hands in humans has become an accepted therapeutic modality. A hand transplant is composed of various tissues of different degree of immunogenicity. In addition, skin contains own resident bacterial flora that may become virulent in the ischemic and rejecting graft. Discrimination between skin rejec...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Studies have documented deficits of pneumococcal and other vaccinations in kidney and lung transplant patients, but the vaccination status of liver transplant (LT) recipients is unknown. This cross-sectional study investigated the prevalence of immunizations among LT patients at a large university medical ce...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.896436
更新日期:2016-04-07 00:00:00
abstract:BACKGROUND:Given the current organ shortage, an accurate assessment of the patient's outcome after orthotopic liver transplantation (OLTX) for fulminant hepatic failure (FHF) is crucial in order to determine the suitability for transplantation. The purpose of this study was to assess whether APACHE II and III scores wo...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Institut Georges Lopez-1 (IGL-1) is a new preservation solution with lower potassium and lower viscosity than University Wisconsin solution (UW). These characteristics which improve liver preservation lead us to evaluate clinical effects of IGL-1 in a randomized controlled study with UW. MATERIAL/METHODS:Fr...
journal_title:Annals of transplantation
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2010-10-01 00:00:00
abstract::Year by year the actual number of transplanted organs has been growing in Poland. In the event of the Województwo Zachodniopomorskie (Western Pomeranian Province) the primary activities were focused on informing medical personnel at hospital departments about approaching donors through trainings for such medical perso...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::BACKGROUND Minimally invasive surgery (MIS) has rapidly advanced, but its use in transplant patients has lagged. We share our experience of MIS for patients after kidney and liver transplantation and compare our results with similar studies in the literature. MATERIAL AND METHODS This study included 14 MIS (12 laparos...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.922602
更新日期:2020-06-16 00:00:00
abstract:BACKGROUND:Transplantation is the only effective method of treatment for end-stage and acute liver failure. Increased average survival time has been observed, and results from improved surgical technique and amended immunosuppression protocols. However, longer survival of patients after orthotopic liver transplantation...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.882005
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Fungal infections have a significant impact on patient survival after liver transplantation, mostly caused by Candida and Aspergillus. The clinical manifestations vary, and range from colonization, active local infection, to severe invasive form. A high degree of suspicion is required for the early diagnosis...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.892132
更新日期:2014-12-22 00:00:00
abstract::102 children have been treated at the Institute of Traumatology, Orthopaedics & Neurosurgery a result of scoliosis. In all of these multi-step treatment has been applied. Initially a telescopic rod was implanted into the spine. Allografts were introduced around the rod hook, after 6 or 8 months, when angle of scoliosi...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Rat pancreatic islets were immunoisolated within alginate capsules with additional polyethyleneimine-protamine-heparin highly biocompatible membrane. Perifusion study in vitro demonstrated satisfactory similarities between the insulin release profiles of encapsulated and free islets. Concordant xenotransplantation of ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Sulforaphane is a naturally occuring antioxidative and anti-inflammatory isothiocyanat. In this study, its impact on experimental kidney transplantation was evaluated. MATERIAL AND METHODS:Male Brown Norway rats (n=112) were used as experimental animals. Donor kidneys were harvested and stored for 12 hours ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.884013
更新日期:2013-09-18 00:00:00
abstract:BACKGROUND:Post kidney transplantation Re-admissions are focused because they are costly and cause morbidity, or may end with unsatisfactory endpoints namely graft loss or death. We compared the pattern, outcome and cost of re-admissions in different post-kidney transplantation periods. MATERIAL/METHODS:In a retrospec...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Expansion of the donor pool by the use of grafts with extended donor criteria reduces waiting list mortality with an increased risk for graft and patient survival after liver transplantation. This study investigates the ability of the Donor-Risk-Index (DRI), the Extended-Criteria-Donor-Score (ECD-score) and ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.883452
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Insufficiency of blood vessels supplying a limb allograft may lead to loss of the extremity. Thus, a regular evaluation of perfusion of transplants seems a reasonable approach. The purpose of the present study was assessment of allograft perfusion by means of non-invasive methods. MATERIAL/METHODS:Six hand ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.892422
更新日期:2014-12-01 00:00:00
abstract::Advances in molecular biology techniques allowed for introduction of PCR-based methods for HLA typing. In routine HLA typing for organ transplantation serological method is still being used as a standard, although molecular techniques are applied more and more often. The aim of our study was to compare HLA-DR typing u...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::This paper outlines the effect that the Transplant Games have had in influencing public opinion and the translation of that effect resulting in increased organ donation and transplantation in the global venues in which this activity took place. A brief account of the history of the Transplant Games now 25 years after ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:In the last three decades liver transplantation (LT) has become a standard procedure for terminal liver failure. Anyway the procedure is highly limited by the availability of donor organs. The use of segmental liver grafts from living or cadaver donors are an attractive way to increase the donor pool for LT ...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::BACKGROUND Organ transplantation is one of the most critical topics in medical ethics that is commonplace in various countries. This study aimed to evaluate the knowledge and the ethical issues surrounding organ transplantation and organ donation among healthcare personnel in Tehran, Iran. MATERIAL AND METHODS In a cr...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.908615
更新日期:2018-05-04 00:00:00
abstract::The aim of the report is to present successful surgical treatment of aneurysm of common iliac artery (CIA) and internal iliac artery (IIA) in a kidney transplant patient. The aneurysm of CIA and IIA, causing arterial hypertension, was diagnosed and treated surgically in a 47-year-old male patient, who had received a c...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::The draft of the working group of experts for a Recommendation of the Committee of Ministers to Member States on Xenotransplantation was finalized in September 2001, ending a working period of two and a half years. This paper will briefly reflect upon the development of the recommendation up to this point in time. A s...
journal_title:Annals of transplantation
pub_type: 指南,杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::BACKGROUND Hyperuricemia is associated with an increased risk of cardiovascular disease and chronic allograft nephropathy after renal transplantation. It has recently been demonstrated that treatment of asymptomatic hyperuricemia is associated with improved patient and graft survival; although, the underlying mechanis...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.901657
更新日期:2017-07-14 00:00:00