Abstract：
:A re-analysis of published data on mouse mutation rates induced by X and gamma rays suggests that the kinetics of induction can be analysed by fitting the data to a parabolic curve. We interpret this to mean that a substantial proportion of the induced mutations results from gross chromosomal changes such as deletions, some of which are one-track and some of which are two-track. This analysis is based on the assumption that the shape of the dose curve, which in the female is concave upward, reflects the manner in which the mutations are induced rather than representing a one-track (linear) curve whose shape has been modified by differential repair.
journal_name
Naturejournal_title
Natureauthors
Abrahamson S,Wolff Sdoi
10.1038/264715a0keywords:
subject
Has Abstractpub_date
1976-12-23 00:00:00pages
715-9issue
5588eissn
0028-0836issn
1476-4687journal_volume
264pub_type
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