Abstract:
:There have been many recent advances in the diagnosis and management of children with retinoblastoma. Regarding diagnosis, the judicial use of ancillary studies, particularly B-scan ultrasonography, has been instrumental in supplementing the diagnosis when opaque media preclude a clear view of the underlying neoplasm. Computed tomography and magnetic resonance imaging are important in the early detection of associated pinealoblastoma, which occurs as part of the recently described syndrome of "trilateral retinoblastoma." With regard to management, the technique of enucleation continues to improve and the scleralized hydroxyapatite implant is now available to provide a better cosmetic appearance and better motility of the artificial eye. Methods have been described for harvesting fresh tumor tissue immediately after enucleation for special DNA studies. Recent reports have documented a decreasing frequency of enucleation and an increasing tendency to use eye-preserving methods of management. Plaque radiotherapy, which provides more localized irradiation to the specific tumor, is gradually supplanting external beam irradiation for localized retinoblastoma that does not exhibit extensive vitreous seeding. The indications and contraindications for cryotherapy and photocoagulation have been more clearly delineated. The role of chemotherapy is being evaluated in the treatment of primary retinoblastoma and for metastatic disease. New breakthroughs in genetic research are being applied to clinical genetic counseling. The prognosis for life and for preservation of vision has improved greatly in recent years.
journal_name
Curr Opin Ophthalmoljournal_title
Current opinion in ophthalmologyauthors
Shields JA,Shields CL,De Potter Pdoi
10.1097/00055735-199406000-00014keywords:
subject
Has Abstractpub_date
1994-06-01 00:00:00pages
83-8issue
3eissn
1040-8738issn
1531-7021journal_volume
5pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:To review the current status of artificial intelligence systems in ophthalmology and highlight the steps required for clinical translation of artificial intelligence into personalized health care (PHC) in retinal disease. RECENT FINDINGS:Artificial intelligence systems for ophthalmological applicatio...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000677
更新日期:2020-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is not to specifically discuss the techniques of veterinary cataract surgery, but rather to emphasize some of the differences between the veterinary and human cataract patients, procedures and outcomes. RECENT FINDINGS:In general, veterinary cataract surgery has more simila...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32831a98aa
更新日期:2009-01-01 00:00:00
abstract:PURPOSE OF REVIEW:A variety of techniques exist for secondary intraocular lens (IOL) implantation. Of note, scleral fixated intraocular lenses have become more popular with a variety of techniques, both with and without use of sutures. Herein, we focus on reviewing recently published studies describing the long-term ou...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000661
更新日期:2020-05-01 00:00:00
abstract::Diabetes and thyroid-related eye disease cause significant morbidity. Although these are endocrine disorders, they cause different ocular manifestations. Previously unexamined epidemiologic factors offer new insight to diabetic eye disease. The association of hyperglycemia, systemic medical therapy, and visual loss is...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199412000-00011
更新日期:1994-12-01 00:00:00
abstract:PURPOSE OF REVIEW:A variety of options exist for perioperative, intraoperative, and postoperative medications in cataract surgery. This article reviews some of the more timely literature on "controversial" subjects in this area. RECENT FINDINGS:Recent literature may support the rationale for intracameral vancomycin at...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200402000-00010
更新日期:2004-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The function is described of the Implantable Miniature Telescope, which is completing clinical development for bilateral end-stage macular degeneration, and 6-month results of the Phase II/III IMT002 prospective, multicenter study are presented. Multispecialty patient management and implications of th...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/01.icu.0000193067.86627.a1
更新日期:2006-02-01 00:00:00
abstract:PURPOSE OF REVIEW:To provide an update on clinical and experimental literature for ocular surface effects of glaucoma therapy and to provide practical guidelines for ophthalmologists treating glaucoma patients with ocular surface disease (OSD). RECENT FINDINGS:Preservatives, notably benzalkonium chloride (BAK), contin...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32835c8aba
更新日期:2013-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Radiation retinopathy remains a devastating cause of visual morbidity in patients undergoing radiation for globe, orbit, and head and neck malignancies. This review discusses the recent efforts of several authors to treat radiation retinopathy once it has developed and efforts to prevent its developme...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000141
更新日期:2015-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To review current concepts and future directions of corneal cross-linking (CXL) as a treatment for keratoconus, ectasia after refractive surgery and infectious keratitis. RECENT FINDINGS:Several important laboratory and clinical studies have established the safety and success of corneal cross-linking...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000146
更新日期:2015-05-01 00:00:00
abstract::Glaucoma surgery has evolved over the past 30 years from the full-thickness procedure to the guarded filtration procedure. However, many of the risks and complications attendant with the full-thickness procedure, including endophthalmitis, hypotony, cataract progression, and filtration failure, continue to plague the ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199904000-00006
更新日期:1999-04-01 00:00:00
abstract:PURPOSE OF REVIEW:As Reese first described the vitreomacular traction (VMT) syndrome in 1970, the knowledge base about the disease has been changing over time due to the advent of the high-definition optical coherence tomography (HD-OCT). The aim of this article was to present the current information on the pathophysio...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e328352404c
更新日期:2012-05-01 00:00:00
abstract::Sjögren syndrome is a chronic systemic disease characterized by polyglandular tissue destruction leading to keratoconjunctivitis sicca (KCS) and xerostomia. Patients with primary Sjögren syndrome show evidence of KCS and xerostomia, whereas patients with secondary Sjögren syndrome suffer from KCS, xerostomia, and an a...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200012000-00011
更新日期:2000-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Review the current management for pediatric nasolacrimal duct obstruction and congenital dacryocele. RECENT FINDINGS:Early probing in the office, and probing beyond 1 year of age in a facility with general anesthesia are equally effective. Congenital nasolacrimal duct obstruction is associated with a...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283642e94
更新日期:2013-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To highlight recent advances in basic research, diagnostic as well as therapeutic advances in ocular parasitosis and to evaluate their application in medical practice. RECENT FINDINGS:Knowledge relating to immunoreactivity in ocular parasitology has grown impressively in past few years. The outcome o...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32833ef67e
更新日期:2010-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose is to summarize treatment strategies in idiopathic intracranial hypertension (IIH), a potentially sight-threatening disease, with a focus on the most current outcome data for venous sinus stenting. RECENT FINDINGS:Historically, the primary treatment options for medically refractory IIH co...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000315
更新日期:2016-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Corneal transplantation is the most commonly performed solid organ transplantation in the world. Despite a glorious history of more than a 100 years, the success of conventional corneal transplantation surgery is marred by problems like graft rejection,graft infection and associated glaucoma due to lo...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:2010-07-01 00:00:00
abstract::Dacryocystorhinostomy remains the mainstay of treatment of acquired primary and secondary obstructions of the lacrimal drainage system. The advent of the endoscope has prompted renewed interest in the intranasal or endonasal approach to fistulae formation. As results of the intranasal approach are reported, they are c...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199610000-00010
更新日期:1996-10-01 00:00:00
abstract:PURPOSE OF REVIEW:This review examines the economic history of refractive surgery and the decline of laser-assisted in-situ keratomileusis (LASIK) in the USA, and the emergence of refractive cataract surgery as an area of growth. RECENT FINDINGS:Since it peaked in 2007 at 1.4 million procedures per year, LASIK has dec...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000159
更新日期:2015-07-01 00:00:00
abstract::Serpiginous choroiditis is a bilateral, inflammatory condition of the inner choroid and overlying retinal pigment epithelium with a distinctive retinal distribution. Although rare, serpiginous choroiditis deserves attention because it can lead to permanent loss of vision due to foveal involvement by inflammation or ch...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200306000-00003
更新日期:2003-06-01 00:00:00
abstract:PURPOSE OF REVIEW:To summarize the ocular and systemic associations of floppy eyelid syndrome (FES) as well as provide an up-to-date review on the pathogenesis and treatment strategies. RECENT FINDINGS:Virtually all patients with FES have obstructive sleep apnea (OSA). However, a significantly lower proportion of pati...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000617
更新日期:2019-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The recent literature was reviewed to analyze the developments in the diagnosis, pathogenesis, and immunology of this group of paraneoplastic syndromes. Clinical features and pathologic findings are summarized. RECENT FINDINGS:The mechanism of cell death in cancer-associated retinopathy appears to oc...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200312000-00017
更新日期:2003-12-01 00:00:00
abstract::The surgical management of Graves ophthalmopathy includes treatment of globe malposition (exophthalmos), strabismus, and eyelid abnormalities. The various techniques used continue to be refined and are detailed in this review. ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199910000-00012
更新日期:1999-10-01 00:00:00
abstract::Ophthalmologic nystagmus can be congenital and manifest/latent both of whose waveforms, compensatory mechanisms, and treatment are different. Physiologically, latent nystagmus may be reversed at will, whereas nystagmus and head nodding may be simultaneously triggered at will. Occasional oscillopsia is more frequent th...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1994-10-01 00:00:00
abstract::Retinopathy of prematurity (ROP) is a potentially blinding condition that afflicts preterm infants in the neonatal period. Although advances in scleral buckling and vitrectomy techniques offer hope for those infants suffering from stage 4 or 5 ROP, prevention of progression to these stages offers the most promise for ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200106000-00003
更新日期:2001-06-01 00:00:00
abstract:PURPOSE OF REVIEW:To review idiopathic orbital inflammation, with particular reference to the evolving entity of ocular adnexal immunoglobulin G4 (IgG4) disease. RECENT FINDINGS:Emerging evidence suggests that sclerosing idiopathic orbital inflammation can be an IgG4-related disease and discovery of this link has furt...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32835563ec
更新日期:2012-09-01 00:00:00
abstract::Porous high-density polyethylene implants have become well accepted for the repair of orbital wall fractures, delayed orbital reconstruction, orbital rim and malar bony onlay augmentation, and volume replacement as orbital spherical implants for the treatment of anophthalmos. Medpor (Porex Surgical, Inc. College Park,...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199710000-00012
更新日期:1997-10-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to describe the current clinical landscape of potential future therapies for both nonexudative (dry) and exudative (wet) age-related macular degeneration (AMD). We highlight some of the more promising treatments that are furthest along in development. RECENT FINDINGS:Pat...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000657
更新日期:2020-05-01 00:00:00
abstract::Outcome measures for studies of the surgical treatment of glaucoma include intraocular pressure, functional status (usually with visual field measurements), and structural status of the optic nerve or nerve fiber layer. Older studies relied heavily and almost solely on intraocular pressure as a surrogate measure for e...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199704000-00013
更新日期:1997-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Molecular genetics is revolutionizing the diagnosis and treatment of inherited eye diseases. The National Eye Institute of the National Institutes of Health (NIH), in an effort to facilitate future basic and clinical research in inherited eye disease, created The National Ophthalmic Disease Genotyping...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32835715c9
更新日期:2012-09-01 00:00:00
abstract::Performing flawless cosmetic blepharoplasty surgery requires attention to many details. A proper medical work-up with establishment of patient rapport and preoperative photographic documentation should begin the evaluation. The surgical correction of concomittant brow position abnormalities should be considered. Res...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199110000-00013
更新日期:1991-10-01 00:00:00