Stress and water balance: the roles of ANP, AVP and isatin.

Abstract:

:Stress is often associated with water retention and its resolution with diuresis. The biological systems for the control of stress and water balance are very closely related. Corticotrophin releasing hormone (CRH) and arginine vasopressin (AVP) are co-localised in the hypothalamus and often act synergistically. Atrial natriuretic peptide (ANP) can exert a feedback control on the hypothalamic/pituitary/adrenal axis. ANP has been shown to be anxiolytic, whereas AVP may be anxiogenic. AVP and ANP levels have been found to be abnormal in a range of stress disorders and psychiatric illnesses. Isatin is an endogenous anxiogenic factor which is also a potent inhibitor of the ANP receptor. It may provide a link between the function of monoamines during stress, and the control of water balance by ANP.

journal_name

Indian J Exp Biol

authors

Bhattacharya SK,Chakrabarti A,Glover V

keywords:

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

1195-200

issue

12

eissn

0019-5189

issn

0975-1009

journal_volume

36

pub_type

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