Candida albicans hyphal invasion: thigmotropism or chemotropism?

Abstract:

:Hyphae of the human pathogenic fungus Candida albicans exhibit thigmotropic behaviour in vitro, in common with phytopathogenic and saprotrophic fungi. An examination of the literature on C. albicans hyphal penetration of epithelial and endothelial membranes does not support the premise that hyphal thigmotropism plays a major role in tissue invasion. Further experimentation is now required to assess thigmotropic behaviour on host membranes and vaginal epithelial cells are suggested as a test model. It is proposed that while thigmotropism may and invasion of tissue invaginations, chemotropism can explain C. albicans hyphal invasion patterns of both endothelium and epithelium.

journal_name

FEMS Microbiol Lett

authors

Davies JM,Stacey AJ,Gilligan CA

doi

10.1111/j.1574-6968.1999.tb13439.x

keywords:

subject

Has Abstract

pub_date

1999-02-15 00:00:00

pages

245-9

issue

2

eissn

0378-1097

issn

1574-6968

pii

S0378-1097(98)00600-4

journal_volume

171

pub_type

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