Death Associated With Coronavirus (COVID-19) Infection in Individuals With Severe Mental Disorders in Sweden During the Early Months of the Outbreak-An Exploratory Cross-Sectional Analysis of a Population-Based Register Study.

Abstract:

:Background: Individuals with severe mental disorder (SMD) have a higher risk of somatic comorbidity and mortality than the rest of the population. We set up a population-based study to assess whether individuals with SMD had a higher risk of death associated with a COVID-19 infection (COVID-19 associated death) than individuals without SMD. Methods: Exploratory analysis with a cross-sectional design in the framework of a population-based register study covering the entire Swedish population. The Swedish Board for Health and Welfare (Socialstyrelsen) provided anonymized tabulated summary data for further analysis. We compared numbers of COVID-19 associated death in individuals with SMD (cases) and without SMD (controls). We calculated the odds ratio (OR) for the whole sample and by age group and four comorbidities, namely diabetes, cardiovascular disease, hypertension, chronic lung disease. Results: The sample comprised of 7,923,859 individuals, 103,999 with SMD and 7,819,860 controls. There were 130 (0.1%) COVID-19 associated deaths in the SMD group and 4,945 (0.06%) in the control group, corresponding to an OR of 1.98 (CI 1.66-2.35; p < 0.001). The odds were 4-fold for the age groups between 60 and 79 years and 1.5-fold for cardiovascular diseases. Individuals with SMD without any of the risk factors under study had 3-fold odds of COVID-19 associated death. Conclusion: Our preliminary results identify individuals with SMD as a further group at increased risk of COVID-19 associated death. In regard to comorbidities, future studies should explore the potential confounding or mediation role in the relationship between SMD and COVID-19 associated deaths.

journal_name

Front Psychiatry

journal_title

Frontiers in psychiatry

authors

Maripuu M,Bendix M,Öhlund L,Widerström M,Werneke U

doi

10.3389/fpsyt.2020.609579

subject

Has Abstract

pub_date

2021-01-08 00:00:00

pages

609579

issn

1664-0640

journal_volume

11

pub_type

杂志文章
  • No Laughing Matter: Presence, Consumption Trends, Drug Awareness, and Perceptions of "Hippy Crack" (Nitrous Oxide) among Young Adults in England.

    abstract::In clinical settings, nitrous oxide gas is a safe anesthetic used during childbirth, in dentistry, and to relieve anxiety in emergencies. Colloquially known as "hippy crack"' or "laughing gas," it is increasingly taken recreationally for its euphoric and relaxing effects and hallucinogenic properties. Using a self-rep...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00312

    authors: Ehirim EM,Naughton DP,Petróczi A

    更新日期:2018-01-22 00:00:00

  • Abnormal Spontaneous Gamma Power Is Associated With Verbal Learning and Memory Dysfunction in Schizophrenia.

    abstract:Background:Schizophrenia patients exhibit cognitive deficits across multiple domains, including verbal memory, working memory, and executive function, which substantially contribute to psychosocial disability. Gamma oscillations are associated with a wide range of cognitive operations, and are important for cortico-cor...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00832

    authors: Tanaka-Koshiyama K,Koshiyama D,Miyakoshi M,Joshi YB,Molina JL,Sprock J,Braff DL,Light GA

    更新日期:2020-08-31 00:00:00

  • The Modified Yale Food Addiction Scale 2.0: Validation Among Non-Clinical and Clinical French-Speaking Samples and Comparison With the Full Yale Food Addiction Scale 2.0.

    abstract:Objectives:The modified Yale Food Addiction Scale 2.0 (mYFAS 2.0) was designed to assess food addiction using a shorter version than the YFAS 2.0. We lack data about the psychometric properties of the mYFAS 2.0 in patients with obesity, as well as studies comparing the psychometric properties of the mYFAS 2.0 versus th...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.480671

    authors: Brunault P,Berthoz S,Gearhardt AN,Gierski F,Kaladjian A,Bertin E,Tchernof A,Biertho L,de Luca A,Hankard R,Courtois R,Ballon N,Benzerouk F,Bégin C

    更新日期:2020-09-08 00:00:00

  • A Closer Look at the Effects of Repeated Cocaine Exposure on Adaptive Decision-Making under Conditions That Promote Goal-Directed Control.

    abstract::It has been proposed that compulsive drug seeking reflects an underlying dysregulation in adaptive behavior that favors habitual (automatic and inflexible) over goal-directed (deliberative and highly flexible) action selection. Rodent studies have established that repeated exposure to cocaine or amphetamine facilitate...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2016.00044

    authors: Halbout B,Liu AT,Ostlund SB

    更新日期:2016-03-21 00:00:00

  • Frequency-Specific Regional Homogeneity Alterations in Tourette Syndrome.

    abstract::Tourette syndrome (TS) is a developmental neuropsychiatric disorder with onset during childhood. Because of its complex spectrum of phenotypes, the underlying pathophysiology of TS is still unclear. Resting-state functional magnetic resonance imaging demonstrated aberrant spontaneous neural synchronization in conventi...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.543049

    authors: Lou YT,Li XL,Wang Y,Ji GJ,Zang YF,Wang J,Feng JH

    更新日期:2020-12-17 00:00:00

  • Changes of Altruistic Behavior and Kynurenine Pathway in Late-Life Depression.

    abstract:Background:Depressive patients show less altruistic behavior. While, older adults present higher tendencies for altruism than younger adults. Depression and age are two of the influencing factors of altruism, kynurenine (KYN), and its metabolites. However, the characteristics of altruism in late-life depression (LLD) a...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00338

    authors: Wu Y,Mai N,Weng X,Liang J,Ning Y

    更新日期:2020-04-30 00:00:00

  • Craving Responses to Methamphetamine and Sexual Visual Cues in Individuals With Methamphetamine Use Disorder After Long-Term Drug Rehabilitation.

    abstract::Studies utilizing functional magnetic resonance imaging (fMRI) cue-reactivity paradigms have demonstrated that short-term abstinent or current methamphetamine (MA) users have increased brain activity in the ventral striatum, caudate nucleus and medial frontal cortex, when exposed to MA-related visual cues. However, pa...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00145

    authors: Huang S,Zhang Z,Dai Y,Zhang C,Yang C,Fan L,Liu J,Hao W,Chen H

    更新日期:2018-04-19 00:00:00

  • Utility of Machine-Learning Approaches to Identify Behavioral Markers for Substance Use Disorders: Impulsivity Dimensions as Predictors of Current Cocaine Dependence.

    abstract:BACKGROUND:Identifying objective and accurate markers of cocaine dependence (CD) can innovate its prevention and treatment. Existing evidence suggests that CD is characterized by a wide range of cognitive deficits, most notably by increased impulsivity. Impulsivity is multidimensional and it is unclear which of its var...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2016.00034

    authors: Ahn WY,Ramesh D,Moeller FG,Vassileva J

    更新日期:2016-03-10 00:00:00

  • Call for Action to Address Equity and Justice Divide During COVID-19.

    abstract::The coronavirus 2019 disease (COVID-19) is deepening the inequity and injustice among the vulnerable communities. The current study aims to present an overview of the impact of COVID-19 on equity and social justice with a focus on vulnerable communities. Vulnerable communities include, but not limited to, healthcare w...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.559905

    authors: Bhaskar S,Rastogi A,Menon KV,Kunheri B,Balakrishnan S,Howick J

    更新日期:2020-12-03 00:00:00

  • Methylphenidate Dose-Dependently Affects Aggression and Improves Fear Extinction and Anxiety in BALB/cJ Mice.

    abstract::Overt aggression, increased anxiety, and dysfunctional fear processing are often observed in individuals with conduct disorder (CD) and attention-deficit hyperactivity disorder (ADHD). Methylphenidate (MPH), a psychostimulant increasing dopamine and noradrenaline tone, is effective in reducing aggression in both CD an...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00768

    authors: Jager A,Kanters D,Geers F,Buitelaar JK,Kozicz T,Glennon JC

    更新日期:2019-10-25 00:00:00

  • Characteristics of Adolescents Affected by Mass Psychogenic Illness Outbreaks in Schools in Nepal: A Case-Control Study.

    abstract::This paper presents the first systematic case-control study of correlates of mass psychogenic illness (MPI) in an adolescent school population. MPI is generally construed as a dissociative phenomenon spread by social contagion to individuals who are prone to dissociation. We sought to test if the correlates of dissoci...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.493094

    authors: Sapkota RP,Brunet A,Kirmayer LJ

    更新日期:2020-11-17 00:00:00

  • Neuroinflammation in Bipolar Depression.

    abstract::Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders. Pathological mechanisms are still vastly unclear, and current treatments with conventional medications are often unsatisfactory in maintaining symptoms control and an adequate quality of life. Consequently, current research is focus...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2020.00071

    authors: Benedetti F,Aggio V,Pratesi ML,Greco G,Furlan R

    更新日期:2020-02-26 00:00:00

  • Mediators Linking Childhood Adversities and Trauma to Suicidality in Individuals at Risk for Psychosis.

    abstract::Suicidality is highly prevalent in patients at clinical high risk (CHR) for psychosis. Childhood adversities and trauma are generally predictive of suicidality. However, the differential effects of adversity/trauma-domains and CHR-criteria, i.e., ultra-high risk and basic symptom criteria, on suicidality remain unclea...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00242

    authors: Schmidt SJ,Schultze-Lutter F,Bendall S,Groth N,Michel C,Inderbitzin N,Schimmelmann BG,Hubl D,Nelson B

    更新日期:2017-11-20 00:00:00

  • The Effect of Insomnia on Cortical Excitability in Patients With Generalized Anxiety Disorder.

    abstract::The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00755

    authors: Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

    更新日期:2019-01-10 00:00:00

  • Transcranial direct current stimulation reduces negative affect but not cigarette craving in overnight abstinent smokers.

    abstract::Transcranial direct current stimulation (tDCS) can enhance cognitive control functions including attention and top-down regulation over negative affect and substance craving in both healthy and clinical populations, including early abstinent (∼1.5 h) smokers. The aim of this study was to assess whether tDCS modulates ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2013.00112

    authors: Xu J,Fregni F,Brody AL,Rahman AS

    更新日期:2013-09-20 00:00:00

  • Parallels and Overlap: The Integration of Homeostatic Signals by Mesolimbic Dopamine Neurons.

    abstract::Motivated behaviors are often initiated in response to perturbations of homeostasis. Indeed, animals and humans have fundamental drives to procure (appetitive behaviors) and eventually ingest (consummatory behaviors) substances based on deficits in body fluid (e.g., thirst) and energy balance (e.g., hunger). Consumpti...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00410

    authors: Hsu TM,McCutcheon JE,Roitman MF

    更新日期:2018-09-03 00:00:00

  • Integrated Mental Health Services for the Developmental Period (0 to 25 Years): A Critical Review of the Evidence.

    abstract::Background: The developmental period from 0 to 25 years is a vulnerable time during which children and young people experience many psychosocial and neurobiological changes and an increased incidence of mental illness. New clinical services for children and young people aged 0 to 25 years may represent a radical trans...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2019.00355

    authors: Fusar-Poli P

    更新日期:2019-06-07 00:00:00

  • Impact of the COVID-19 Pandemic on Patients With Alcohol Use Disorder and Associated Risk Factors for Relapse.

    abstract::Background: The impact of the ongoing COVID-19 pandemic on vulnerable groups like patients suffering from substance use disorders is expected to be tremendous, and corresponding concerns were raised early on by many experts around the world. Psychosocial distress, financial insecurities and physiological problems asso...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.620612

    authors: Yazdi K,Fuchs-Leitner I,Rosenleitner J,Gerstgrasser NW

    更新日期:2020-12-16 00:00:00

  • The Associations of Emotion Coping Appraisal With Both the Cue-Outcome Contingency and Perceived Verbal Abuse Exposure.

    abstract::Previous studies have reported an association between verbal abuse in early childhood and structural and functional alterations in the young adult brain, supporting the existence of critical periods in human brain development. In addition, exposure to verbal abuse in early childhood is strongly correlated with lifetim...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00250

    authors: Shin DW,Yoon T,Jeong B

    更新日期:2019-04-16 00:00:00

  • Consumer Perspectives of Safewards Impact in Acute Inpatient Mental Health Wards in Victoria, Australia.

    abstract::Background: Inpatient mental health wards are reported by many consumers to be custodial, unsafe, and lacking in therapeutic relationships. These consumer experiences are concerning, given international policy directives requiring recovery-oriented practice. Safewards is both a model and a suite of interventions desig...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00461

    authors: Fletcher J,Buchanan-Hagen S,Brophy L,Kinner SA,Hamilton B

    更新日期:2019-07-09 00:00:00

  • Suicidal Ideation in Newly-Diagnosed Chinese Cancer Patients.

    abstract:Objective:Suicide is one of the main reasons cited behind the death rate of cancer, and suicidal ideation (SI) is the first step toward it. This study aimed to investigate the prevalence and associates of suicidal ideation in newly-diagnosed Chinese cancer patients. Methods:This multicenter study was conducted from Ja...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00708

    authors: Zhang Y,Li W,Zhang Z,Sun H,Garg S,Yang Y,Wang H

    更新日期:2020-07-23 00:00:00

  • Involuntary Autobiographical Memories in Schizophrenia: Characteristics and Conditions of Elicitation.

    abstract::Involuntary autobiographical memories are mental representations of personally experienced past events that come to mind spontaneously, with no preceding attempt to recall them. They have been showed to be more frequent and more emotional in the psychosis continuum. Although schizophrenia is strongly associated with t...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.567189

    authors: Allé MC,Berna F,Danion JM,Berntsen D

    更新日期:2020-10-09 00:00:00

  • Defining a Brief Intervention for the Promotion of Psychological Well-being among Unemployed Individuals through Expert Consensus.

    abstract:Background:Epidemiologic evidence highlights the harmful consequences of unemployment on health and well-being. This emphasizes the need to design low-cost interventions to prevent the adverse mental health effects of unemployment. The main aim of this study was to create expert-consensus regarding development and impl...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00013

    authors: Santos O,Lopes E,Virgolino A,Stefanovska-Petkovska M,Dinis A,Ambrósio S,Heitor MJ

    更新日期:2018-02-07 00:00:00

  • A Medicinal Herb Scutellaria lateriflora Inhibits PrP Replication in vitro and Delays the Onset of Prion Disease in Mice.

    abstract::Transmissible spongiform encephalopathies (TSE) are characterized by the misfolding of the host encoded prion protein (PrP(C)) into a pathogenic isoform (PrP(Sc)) which leads to the accumulation of β-sheet-rich fibrils and subsequent loss of neurons and synaptic functions. Although many compounds have been identified ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2012.00009

    authors: Eiden M,Leidel F,Strohmeier B,Fast C,Groschup MH

    更新日期:2012-02-17 00:00:00

  • Text Analysis of Electronic Medical Records to Predict Seclusion in Psychiatric Wards: Proof of Concept.

    abstract::Aim: With the introduction of "Electronic Medical Record" (EMR) a wealth of digital data has become available. This provides a unique opportunity for exploring precedents for seclusion. This study explored the feasibility of text mining analysis in the EMR to eventually help reduce the use of seclusion in psychiatry. ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00188

    authors: Hazewinkel MC,de Winter RFP,van Est RW,van Hyfte D,Wijnschenk D,Miedema N,Hoencamp E

    更新日期:2019-04-11 00:00:00

  • Social Attention in Autism: Neural Sensitivity to Speech Over Background Noise Predicts Encoding of Social Information.

    abstract::Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by lack of attention to social cues in the environment, including speech. Hypersensitivity to sensory stimuli, such as loud noises, is also extremely common in youth with ASD. While a link between sensory hypersensitivity and impaired social...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00343

    authors: Hernandez LM,Green SA,Lawrence KE,Inada M,Liu J,Bookheimer SY,Dapretto M

    更新日期:2020-04-24 00:00:00

  • Baclofen for the Treatment of Alcohol Use Disorder in Patients With Liver Cirrhosis: 10 Years After the First Evidence.

    abstract::Alcohol Use Disorder (AUD) is a chronic and relapsing condition characterized by harmful alcohol intake and behavioral-cognitive changes. AUD is the most common cause of liver disease in the Western world. Alcohol abstinence is the cornerstone of therapy in alcoholic patients affected with liver disease. Medical recom...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00474

    authors: Mosoni C,Dionisi T,Vassallo GA,Mirijello A,Tarli C,Antonelli M,Sestito L,Rando MM,Tosoni A,De Cosmo S,Gasbarrini A,Addolorato G

    更新日期:2018-10-01 00:00:00

  • The Attribution of Mental Health Problems to Jinn: An Explorative Study in a Transcultural Psychiatric Outpatient Clinic.

    abstract:Background:Among Muslim patients, a common cultural concept of distress is the notion that jinn may be the cause of mental health problems, especially in the presence of hallucinations. Objective:This study examines the frequency with which this attribution style is manifest in a specific psychiatric outpatient popula...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00089

    authors: Lim A,Hoek HW,Ghane S,Deen M,Blom JD

    更新日期:2018-03-28 00:00:00

  • Siblings of Individuals With Eating Disorders: A Review of the Literature.

    abstract::Eating disorders (EDs) are serious psychopathologies characterized by a persistent disturbance in eating or eating-related behavior. Studies have shown EDs' detrimental consequences not only for patients, but also for their families. Nevertheless, a specific group that has so far been neglected, in both the research a...

    journal_title:Frontiers in psychiatry

    pub_type:

    doi:10.3389/fpsyt.2020.00604

    authors: Maon I,Horesh D,Gvion Y

    更新日期:2020-06-30 00:00:00

  • Functional Connectivity of Cognitive Brain Networks in Schizophrenia during a Working Memory Task.

    abstract::Task-based connectivity studies facilitate the understanding of how the brain functions during cognition, which is commonly impaired in schizophrenia (SZ). Our aim was to investigate functional connectivity during a working memory task in SZ. We hypothesized that the task-negative (default mode) network and the cognit...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00294

    authors: Godwin D,Ji A,Kandala S,Mamah D

    更新日期:2017-12-22 00:00:00