Burden of depression and anxiety among leprosy affected and associated factors-A cross sectional study from India.

abstract：BACKGROUND:Crimean-Congo hemorrhagic fever (CCHF) is a serious disease with a high fatality rate reported in many countries. The first case of CCHF in Oman was detected in 1995 and serosurveys have suggested widespread infection of humans and livestock throughout the country. METHODOLOGY:Cases of CCHF reported to the ...

journal_title：PLoS neglected tropical diseases

authors： Al-Abri SS,Hewson R,Al-Kindi H,Al-Abaidani I,Al-Jardani A,Al-Maani A,Almahrouqi S,Atkinson B,Al-Wahaibi A,Al-Rawahi B,Bawikar S,Beeching NJ

更新日期：2019-04-25 00:00:00

abstract：:Leishmaniasis is a major health problem in some endemic areas and yet, no vaccine is available against any form of the disease. Historically, leishmanization (LZ) which is an inoculation of individual with live Leishmania, is the most effective control measure at least against cutaneous leishmaniasis (CL). Due to vari...

journal_title：PLoS neglected tropical diseases

authors： Davoudi N,Khamesipour A,Mahboudi F,McMaster WR

更新日期：2014-05-29 00:00:00

abstract：BACKGROUND:The impact of large scale Mass Drug Adminstration (MDA) of ivermectin on active onchocerciasis transmission by Simulium damnosum, which transmits the parasite O. volvulus is of great importance for onchocerciasis control programmes. We investigated in the Mbam river system area, the impact of MDA of ivermect...

journal_title：PLoS neglected tropical diseases

authors： Abong RA,Amambo GN,Hamid AA,Enow BA,Beng AA,Nietcho FN,Nji TM,Njouendou AJ,Ritter M,Esum ME,Deribe K,Cho JF,Fombad FF,Enyong PI,Poole C,Pfarr K,Hoerauf A,Carlow C,Wanji S

更新日期：2021-01-19 00:00:00

abstract：:While the incidence of Human African Trypanosomiasis (HAT) is decreasing, the control approach is shifting from active population screening by mobile teams to passive case detection in primary care centers. We conducted a systematic review of the literature between 1970 and 2011 to assess which diagnostic tools are mo...

journal_title：PLoS neglected tropical diseases

authors： Mitashi P,Hasker E,Lejon V,Kande V,Muyembe JJ,Lutumba P,Boelaert M

更新日期：2012-01-01 00:00:00

abstract：:Chikungunya virus (CHIKV) infection is characterized by rash, acute high fever, chills, headache, nausea, photophobia, vomiting, and severe polyarthralgia. There is evidence that arthralgia can persist for years and result in long-term discomfort. Neurologic disease with fatal outcome has been documented, although at ...

journal_title：PLoS neglected tropical diseases

authors： van den Doel P,Volz A,Roose JM,Sewbalaksing VD,Pijlman GP,van Middelkoop I,Duiverman V,van de Wetering E,Sutter G,Osterhaus AD,Martina BE

更新日期：2014-09-04 00:00:00

abstract：:Aedes aegypti is the primary vector of several medically relevant arboviruses including dengue virus (DENV) types 1-4. Ae. aegypti transmits DENV by inoculating virus-infected saliva into host skin during probing and feeding. Ae. aegypti saliva contains over one hundred unique proteins and these proteins have diverse ...

journal_title：PLoS neglected tropical diseases

authors： Conway MJ,Londono-Renteria B,Troupin A,Watson AM,Klimstra WB,Fikrig E,Colpitts TM

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND:Loiasis, a filarial infection caused by Loa loa usually thought to cause relatively minor morbidity, can cause serious and often fatal reactions in patients carrying very high levels of circulating Loa loa microfilariae (mf) following administration of microfilaricidal drugs. An experimental model of this co...

journal_title：PLoS neglected tropical diseases

authors： Wanji S,Eyong EE,Tendongfor N,Ngwa C,Esuka E,Kengne-Ouafo A,Datchoua-Poutcheu F,Enyong P,Hopkins A,Mackenzie CD

更新日期：2015-11-10 00:00:00

abstract：:Tanzania has recently experienced outbreaks of dengue in two coastal regions of Dar es Salaam and Tanga. Chikungunya and Rift Valley Fever outbreaks have also been recorded in the past decade. Little is known on the burden of the arboviral disease causing viruses (Dengue, Rift Valley and Chikungunya) endemically in th...

journal_title：PLoS neglected tropical diseases

authors： Budodo RM,Horumpende PG,Mkumbaye SI,Mmbaga BT,Mwakapuja RS,Chilongola JO

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:On the Zanzibar islands, United Republic of Tanzania, elimination of urogenital schistosomiasis is strived for in the coming years. This qualitative study aimed to better understand community knowledge, perceptions, and practices associated with schistosomiasis among school-aged children on Unguja and Pemba ...

journal_title：PLoS neglected tropical diseases

authors： Person B,Ali SM,A'Kadir FM,Ali JN,Mohammed UA,Mohammed KA,Rollinson D,Knopp S

更新日期：2016-07-11 00:00:00

abstract：BACKGROUND:Vector control remains the primary method to prevent dengue infections. Environmental interventions represent sustainable and safe methods as there are limited risks of environmental contamination and toxicity. The objective of this study is to perform a systematic review and meta-analysis of the effectivene...

journal_title：PLoS neglected tropical diseases

authors： Buhler C,Winkler V,Runge-Ranzinger S,Boyce R,Horstick O

更新日期：2019-07-11 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is an important flavivirus infection. Although ZIKV infection is rarely fatal, risk for severe disease in adults is not well described. Our objective was to describe the spectrum of illness in U.S. Veterans with ZIKV infection. METHODOLOGY:Case series study including patients with laborato...

journal_title：PLoS neglected tropical diseases

authors： Schirmer PL,Wendelboe A,Lucero-Obusan CA,Ryono RA,Winters MA,Oda G,Martinez M,Saavedra S,Holodniy M

更新日期：2018-05-24 00:00:00

abstract：:Theileria parva is an economically important, intracellular, tick-transmitted parasite of cattle. A live vaccine against the parasite is effective against challenge from cattle-transmissible T. parva but not against genotypes originating from the African Cape buffalo, a major wildlife reservoir, prompting the need to ...

journal_title：PLoS neglected tropical diseases

authors： Palmateer NC,Tretina K,Orvis J,Ifeonu OO,Crabtree J,Drabék E,Pelle R,Awino E,Gotia HT,Munro JB,Tallon L,Morrison WI,Daubenberger CA,Nene V,Knowles DP,Bishop RP,Silva JC

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Large-scale deworming programs have, to date, mostly targeted preschool- and school-age children. As community-based deworming programs become more common, deworming will be offered to women of reproductive age. The World Health Organization recommends preventive chemotherapy be administered to pregnant wome...

journal_title：PLoS neglected tropical diseases

authors： St-Denis K,Blouin B,Rahme E,Casapia M,Montresor A,Mupfasoni D,Mbabazi PS,Gyorkos TW

更新日期：2020-01-30 00:00:00

abstract：:Genomic data generated from clinical Vibrio cholerae O1 isolates collected over a five year period in an area of Kolkata, India with seasonal cholera outbreaks allowed a detailed genetic analysis of serotype switching that occurred from Ogawa to Inaba and back to Ogawa. The change from Ogawa to Inaba resulted from mut...

journal_title：PLoS neglected tropical diseases

authors： Karlsson SL,Thomson N,Mutreja A,Connor T,Sur D,Ali M,Clemens J,Dougan G,Holmgren J,Lebens M

更新日期：2016-10-05 00:00:00

abstract：BACKGROUND:Central nervous system (CNS) infections are important diseases in both children and adults worldwide. The spectrum of infections is broad, encompassing bacterial/aseptic meningitis and encephalitis. Viruses are regarded as the most common causes of encephalitis and aseptic meningitis. Better understanding of...

journal_title：PLoS neglected tropical diseases

authors： Tan le V,Thai le H,Phu NH,Nghia HD,Chuong LV,Sinh DX,Phong ND,Mai NT,Man DN,Hien VM,Vinh NT,Day J,Chau NV,Hien TT,Farrar J,de Jong MD,Thwaites G,van Doorn HR,Chau TT

更新日期：2014-08-28 00:00:00

abstract：:Between March 2014 and July 2015 at least 10,500 Ebola cases including more than 4,800 deaths occurred in Liberia, the majority in Monrovia. However, official numbers may have underestimated the size of the outbreak. Closure of health facilities and mistrust in existing structures may have additionally impacted on all...

journal_title：PLoS neglected tropical diseases

authors： Kuehne A,Lynch E,Marshall E,Tiffany A,Alley I,Bawo L,Massaquoi M,Lodesani C,Le Vaillant P,Porten K,Gignoux E

更新日期：2016-08-23 00:00:00

abstract：BACKGROUND:Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS. Despite recent successes in arresting transmission, some 40 million people who already have the disease have been largely neglected. This study...

journal_title：PLoS neglected tropical diseases

authors： Perera M,Whitehead M,Molyneux D,Weerasooriya M,Gunatilleke G

更新日期：2007-11-21 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) continues to challenge Asia with pandemic potential. In Vietnam, there have been two major outbreaks occurring during 2011-2012 (>200,000 hospitalizations and >200 deaths) and more recently in 2018 (>130,000 hospitalizations and 17 deaths). Given the high burden and the complex epid...

journal_title：PLoS neglected tropical diseases

authors： Nhan LNT,Khanh TH,Hong NTT,Van HMT,Nhu LNT,Ny NTH,Nguyet LA,Thanh TT,Anh NT,Hang VTT,Qui PT,Viet HL,Tung TH,Ha DQ,Tuan HM,Thwaites G,Chau NVV,Thwaites L,Hung NT,van Doorn HR,Tan LV

更新日期：2020-08-17 00:00:00

abstract：:The agents of sleeping sickness disease, Trypanosoma brucei complex parasites, are transmitted to mammalian hosts through the bite of an infected tsetse. Information on tsetse-trypanosome interactions in the salivary gland (SG) tissue, and on mammalian infective metacyclic (MC) parasites present in the SG, is sparse. ...

journal_title：PLoS neglected tropical diseases

authors： Telleria EL,Benoit JB,Zhao X,Savage AF,Regmi S,Alves e Silva TL,O'Neill M,Aksoy S

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB), is composed of eight subspecies. TB in West Africa, in contrast to other geographical regions, is caused by Mycobacterium africanum (MAF) in addition to M. tuberculosis (MTB), with both infections presenting similar symptoms...

journal_title：PLoS neglected tropical diseases

authors： Namasivayam S,Diarra B,Diabate S,Sarro YDS,Kone A,Kone B,Tolofoudie M,Baya B,Diakite MT,Kodio O,Cohen K,Holl J,Achenbach CJ,Chatterjee S,Murphy RL,Bishai W,Diallo S,Sher A,Maiga M

更新日期：2020-05-13 00:00:00

abstract：:In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains' morphological and cytological features. However, further aerobic culture of the black grains generated a melanised fungu...

journal_title：PLoS neglected tropical diseases

authors： Mhmoud NA,Santona A,Fiamma M,Siddig EE,Deligios M,Bakhiet SM,Rubino S,Fahal AH

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:Schistosomiasis remains a global public health challenge, with 93% of the ~237 million infections occurring in sub-Saharan Africa. Though rarely fatal, its recurring nature makes it a lifetime disorder with significant chronic health burdens. Much of its negative health impact is due to non-specific conditio...

journal_title：PLoS neglected tropical diseases

authors： Terer CC,Bustinduy AL,Magtanong RV,Muhoho N,Mungai PL,Muchiri EM,Kitron U,King CH,Mutuku FM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania species. While HASPs are antigenic in the host and can induc...

journal_title：PLoS neglected tropical diseases

authors： Depledge DP,MacLean LM,Hodgkinson MR,Smith BA,Jackson AP,Ma S,Uliana SR,Smith DF

更新日期：2010-09-28 00:00:00

abstract：BACKGROUND:Although increased capillary permeability is the major clinical feature associated with severe dengue infections the mechanisms underlying this phenomenon remain unclear. Dextran clearance methodology has been used to investigate the molecular sieving properties of the microvasculature in clinical situations...

journal_title：PLoS neglected tropical diseases

authors： Nguyen-Pouplin J,Pouplin T,Van TP,The TD,Thi DN,Farrar J,Tinh HT,Wills B

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is an emergent threat provoking a worldwide explosive outbreak. Since January 2015, 41 countries reported autochthonous cases. In Brazil, an increase in Guillain-Barré syndrome and microcephaly cases was linked to ZIKV infections. A recent report describing low experimental transmission eff...

journal_title：PLoS neglected tropical diseases

authors： Bonaldo MC,Ribeiro IP,Lima NS,Dos Santos AA,Menezes LS,da Cruz SO,de Mello IS,Furtado ND,de Moura EE,Damasceno L,da Silva KA,de Castro MG,Gerber AL,de Almeida LG,Lourenço-de-Oliveira R,Vasconcelos AT,Brasil P

更新日期：2016-06-24 00:00:00

abstract：:Australia is currently canine rabies free. However, communities located on the northern coastline-such as the Northern Peninsula Area (NPA), Queensland-are at risk of an incursion due to their large populations of susceptible free-roaming dogs and proximity to rabies-infected Indonesian islands. A rabies-spread model ...

journal_title：PLoS neglected tropical diseases

authors： Hudson EG,Brookes VJ,Dürr S,Ward MP

更新日期：2019-07-08 00:00:00

abstract：:Pathogens originating from wildlife (zoonoses) pose a significant public health burden, comprising the majority of emerging infectious diseases. Efforts to control and prevent zoonotic disease have traditionally focused on animal-to-human transmission, or "spillover." However, in the modern era, increasing internation...

journal_title：PLoS neglected tropical diseases

authors： Guth S,Hanley KA,Althouse BM,Boots M

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND:Group 2 Innate lymphoid cells (ILC2s) are innate cells that produce the TH2 cytokines IL-5 and IL-13. The importance of these cells has recently been demonstrated in experimental models of parasitic diseases but there is a paucity of data on ILC2s in the context of human parasitic infections and in particula...

journal_title：PLoS neglected tropical diseases

authors： Nausch N,Appleby LJ,Sparks AM,Midzi N,Mduluza T,Mutapi F

更新日期：2015-03-23 00:00:00

abstract：BACKGROUND:Talaromyces marneffei is an opportunistic dimorphic fungus prevalent in Southeast Asia. We previously demonstrated that Mp1p is an immunogenic surface and secretory mannoprotein of T. marneffei. Since Mp1p is a surface protein that can generate protective immunity, we hypothesized that Mp1p and/or its homolo...

journal_title：PLoS neglected tropical diseases

authors： Woo PC,Lau SK,Lau CC,Tung ET,Chong KT,Yang F,Zhang H,Lo RK,Cai JP,Au-Yeung RK,Ng WF,Tse H,Wong SS,Xu S,Lam WH,Tse MK,Sze KH,Kao RY,Reiner NE,Hao Q,Yuen KY

更新日期：2016-08-25 00:00:00

abstract：:Infection with the intracellular protozoan parasite Leishmania mexicana causes chronic disease in C57BL/6 mice, in which cutaneous lesions persist for many months with high parasite burdens (10(7)-10(8) parasites). This chronic disease process requires host IL-10 and FcγRIII. When Leishmania amastigotes are released f...

journal_title：PLoS neglected tropical diseases

authors： Buxbaum LU

更新日期：2013-05-09 00:00:00