Retracted: Ursolic Acid Exhibits Potent Anticancer Effects in Human Metastatic Melanoma Cancer Cells (SK-MEL-24) via Apoptosis Induction, Inhibition of Cell Migration and Invasion, Cell Cycle Arrest, and Inhibition of Mitogen-Activated Protein Kinase (MAP

abstract：:BACKGROUND Numerous studies have evaluated the relationship between RNASEL gene polymorphisms (rs486907 G>A and rs627928 T>G) and the risk of cancer. However, many of the results have been controversial. To explore the role of RNASEL gene polymorphisms in prostate cancer, we carried out the present meta-analysis. MATE...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xia J,Sun R

更新日期：2019-11-05 00:00:00

abstract：:Selective COX-2 inhibitors increase the risk of myocardial infarction and stroke that is attributed to their ability to inhibit prostacyclin (PGI2), lipoxins, resolvins, and endothelial nitric oxide (eNO) but not platelet COX-1 derived thromboxane A2 (TXA2). In contrast, aspirin blocks both COX-1 and COX-2 enzymes tha...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Das UN

更新日期：2005-07-01 00:00:00

abstract：:BACKGROUND Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in one-carbon cell metabolism, including in liver cancer. However, the associations between SHMT2 expression at the gene and protein level and prognosis in patients with hepatocellular carcinoma (HCC) remains unknown. This study aimed to investigate ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ji L,Tang Y,Pang X,Zhang Y

更新日期：2019-08-05 00:00:00

abstract：:BACKGROUND To identify the overall effects of pulmonary thromboembolism (PTE) on the heart, we evaluated the heart findings and clinical characteristics of deceased patients diagnosed with PTE. MATERIAL AND METHODS PTEs were classified into 2 categories: fatal and contributory. Cases with a history of cardiopulmonary ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yakar A,Yakar F,Ziyade N,Yıldız M,Üzün İ

更新日期：2016-04-27 00:00:00

abstract：BACKGROUND:We set out to detect whether morphine is present in tissue taken from a patient with intractable temporal lobe epilepsy and to characterize the presence and nature of mu opiate receptor subtypes in this tissue. CASE REPORT:In temporal lobe tissue, resected during anteromedial temporal lobectomy for intracta...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Fricchione G,Zhu W,Cadet P,Mantione KJ,Bromfield E,Madsen J,DeGirolami U,Dworetzky B,Vaccaro B,Black P,Stefano GB

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The humanized anti-HER2 monoclonal antibody trastuzumab (Herceptin) is useful in the treatment of ErbB2-overexpressing breast cancers, but its efficiency is limited because development of resistance is common. In order to study the possibility of improving the efficacy of therapies directed against HER2/erbB...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Camirand A,Lu Y,Pollak M

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The aim of the conducted study was to analyze the phenomenon of Couvade Syndrome amongst fathers expecting their children in Poland. The authors examined the frequency of couvade symptoms in male subjects as well as their associations with male empathy. MATERIAL AND METHODS:The research involved 143 expecta...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kazmierczak M,Kielbratowska B,Pastwa-Wojciechowska B

更新日期：2013-02-21 00:00:00

abstract：:BACKGROUND The purpose of this study was to evaluate the utility of multi-detector computed tomography (MDCT) angiography and transthoracic echocardiography (TTE) in the diagnosis of congenital coarctation of the aorta (CoA) and accompanying malformations in infants. MATERIAL AND METHODS From January 2012 and December...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang F,Chen Q,Huang WH,Wu H,Li WC,Lai QQ

更新日期：2017-05-16 00:00:00

abstract：BACKGROUND:Retinoblastoma (Rb) is the most common primary malignant intraocular tumour in childhood. The "two hit" theory, formulated by Knudson in 1971 to explain the variegated clinical expression of the disease, led to the discovery of the so called tumour suppressor genes and the identification of the Rb1 as the pr...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Mastrangelo D,De Francesco S,Di Leonardo A,Lentini L,Hadjistilianou T

更新日期：2008-12-01 00:00:00

abstract：:BACKGROUND Non-small cell lung cancer (NSCLC) accounts for about 85% of all types of lung cancer. Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is involved in DNA methylation, and DNA methylation is related to tumorigenesis. The role of MTHFD1 in NSCLC was examined in our study. MATERIAL AND METHODS The correlati...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ding K,Jiang J,Chen L,Xu X

更新日期：2018-10-21 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) refers to acute renal damage that occurs after the use of contrast agents. This study investigated the renal protective effect of probucol in a rat model of contrast-induced nephropathy and the mechanism of its effect. MATERIAL AND METHODS:Twenty-eight Wistar rats were ran...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang N,Wei RB,Li QP,Yang X,Li P,Huang MJ,Wang R,Cai GY,Chen XM

更新日期：2015-09-26 00:00:00

abstract：:BACKGROUND The imbalance between bone resorption and formation is the basic mechanism underlying osteoporosis in the elderly. Osteogenesis is the differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts. Sirtuin6 (SIRT6) regulates various biological functions, including differentiation. Transient recep...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xiao F,Zhou Y,Liu Y,Xie M,Guo G

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:Previous studies have shown that administration of ghrelin exhibits protective and therapeutic effects in the gut. The aim of the present investigation was to examine the influence of ghrelin administration on the course of cysteamine-induced duodenal ulcers, as well as effects on mucosal production of oxyge...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Warzecha Z,Ceranowicz D,Dembiński A,Ceranowicz P,Cieszkowski J,Kuwahara A,Kato I,Dembiński M,Konturek PC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Not all coronary events occur in young individuals with traditional risk factors. In recent years some authors have observed increased prevalence of elevated anti-phospholipid (aPL) antibodies in young patients with myocardial infarction. Also, thickening of the combined arterial intima-media thickness (IMT)...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dropiński J,Szczeklik W,Rubiś P,Sydor WJ

更新日期：2003-04-01 00:00:00

abstract：:BACKGROUND The objective of this study was to identify the pathway responsible for ventricular remodeling. MATERIAL AND METHODS We collected remodeling myocardium tissue (n=18) and control myocardium tissue (n=22), and detected the expression of 4 miRNAs in these 2 groups using real-time PCR. We then searched the miRN...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang J,Qin L,Han L,Zhao Y,Jing H,Song W,Shi H

更新日期：2017-08-17 00:00:00

abstract：:BACKGROUND Piwi-interacting RNA (piRNA) is the largest class of small non-coding RNA, which has also been identified in somatic tissues, and aberrant expression of piRNAs in tumor tissues may be implicated in carcinogenesis. piR-823 is increased in liver cirrhosis and hepatocellular carcinoma (HCC). However, there is n...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tang X,Xie X,Wang X,Wang Y,Jiang X,Jiang H

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:Xeroderma pigmentosum group F (XPF) is an important participant in the nucleotide excision repair process. This study aimed to investigate the expression of DNA repair gene xeroderma pigmentosum group F (XPF) in bladder cancer and its clinical significance. MATERIAL/METHODS:Total RNA and protein were extrac...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li J,Zhang J,Liu Y,Ye G

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Problematic bacteria in the community include enterobacteria which produce extended-spectrum beta-lactamases. As yet there is no description of the prevalence of these bacteria in persons in the community in the Czech Republic. Therefore the main goal of this study was to determine the prevalence of ESBL-pos...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cekanová L,Kolár M,Chromá M,Sauer P,Sedlácková M,Koukalová D

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The establishment of Helicobacter pylori in the stomach and duodenum is associated with gastritis, peptic ulcers, and gastric cancer. Application of suitable methods, including molecular techniques, for an accurate detection of H. pylori can lead to the administration of appropriate drugs and successful ther...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tajbakhsh S,Samarbaf-Zadeh AR,Moosavian M

更新日期：2008-09-01 00:00:00

abstract：:BACKGROUND The current research work aimed to explore the protective role of myricetin against cataractogenesis in humans, in terms of its anti-apoptotic potential. MATERIAL AND METHODS Human eye lens epithelial cells were exposed to oxidative stress by treating with hydrogen peroxide (H₂O₂). The levels of superoxide ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yang Y,Xu X,Liu Q,Huang H,Huang X,Lv H

更新日期：2020-04-26 00:00:00

abstract：:BACKGROUND Hepatitis B virus (HBV) genotypes show genomic variations, resulting in different CpG islands in each HBV genotypes or subgenotype. This study aimed to establish reference sequences for each HBV subgenotype of A-H genotypes and to analyze the characteristics of the CpG islands. MATERIAL AND METHODS There we...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen L,Shi Y,Yang W,Zhang Y,Xie Q,Li Y,Li X,Li J,Zhang Z

更新日期：2018-09-25 00:00:00

abstract：BACKGROUND:In recent years, extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae have emerged in many hospitals worldwide. The increasing dissemination and long-term carriage of these organisms within the community carry tremendous implications on the empirical therapy of community-acquired infection. ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Borer A,Gilad J,Menashe G,Peled N,Riesenberg K,Schlaeffer F

更新日期：2002-01-01 00:00:00

abstract：:BACKGROUND Piperine has been reported to inhibit proliferation and induce apoptosis in various cancer cells. This study aimed to explore the efficacy and underlying mechanism of piperine in human gastric cancer. MATERIAL AND METHODS MTT assay was performed to examine the effect of piperine (concentrations of 0-300 μM)...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen H,Sheng H,Zhao Y,Zhu G

更新日期：2020-12-31 00:00:00

abstract：BACKGROUND:The increased permeability of the glomerular capillary wall in adriamycin nephropathy may be mediated by increased generation of free radicals, possibly also by the non-enzymatic production of isoprostanes induced by oxidative stress. ACE inhibitors and angiotensin II antagonists may reduce proteinuria, perh...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tesar V,Zima T,Jirsa M Jr,Crkovská J,Stípek S,Vernerová Z,Seráková M

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to contrast the collapse values of the postoperative weight-bearing areas of different tantalum rod implant positions, fibula implantation, and core decompression model and to investigate the advantages and disadvantages of tantalum rod implantation in different ranges of osteonecro...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Shi J,Chen J,Wu J,Chen F,Huang G,Wang Z,Zhao G,Wei Y,Wang S

更新日期：2014-12-06 00:00:00

abstract：:BACKGROUND Despite noteworthy advancements in the multidisciplinary treatment of colorectal cancer (CRC) and deeper understanding in the molecular mechanisms of CRC, many of CRC patients with histologically identical tumors present different treatment response and prognosis. Thus, more evidence on novel predictive and...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu X,Bing Z,Wu J,Zhang J,Zhou W,Ni M,Meng Z,Liu S,Tian J,Zhang X,Li Y,Jia S,Guo S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:With the advent of superb microsurgery techniques and advanced stabilization instruments, recent decades have seen great progress in treating nonunions secondary to traumatic fractures. However, those nonunions that are secondary to primary non-Hodgkin's lymphoma of bone and often related to irradiation stil...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xie XT,Gao YS,Zhang CQ

更新日期：2011-11-01 00:00:00

abstract：:The methods of increasing the efficacy of thrombolysis under clinical and experimental conditions are have been discussed in the light of analysis of current tendencies in the investigation and development of thrombolytic and adjunctive therapy. Analysis of the data obtained in the search for novel plasminogen activat...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Maksimenko AV

更新日期：2002-01-01 00:00:00

abstract：:BACKGROUND Diabetes is a risk factor for coronary atherosclerosis and coronary heart disease. Resveratrol (RESV) is a natural compound with anti-inflammatory effects. The objective of this study is to evaluate the cardio protective effects of RESV in a diabetic rat model with coronary heart disease. MATERIAL AND METHO...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huo X,Zhang T,Meng Q,Li C,You B

更新日期：2019-01-18 00:00:00

abstract：:BACKGROUND Esophageal squamous cell carcinoma (ESCC), a major histological subtype of esophageal cancer, is a common cause of tumor-related deaths in the world. Due to the lack of understanding of the pathogenesis of ESCC, its clinical treatment is still a big challenge. In the present study, we aimed to identify an E...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang X,Gu M,Ju Y,Zhou J

更新日期：2020-03-24 00:00:00