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Respiratory Syncytial Virus Infection: Its Propensity for Bacterial Coinfection and Related Mortality in Elderly Adults.

Abstract：

:Respiratory syncytial virus (RSV) is an increasingly recognized cause of acute respiratory infection (ARI) in adults. We compared the crude in-hospital mortality of patients with RSV infection alone with that of patients with RSV-bacterial coinfection. Overall, 12 144 hospitalized patients with ARI were screened for RSV detection by polymerase chain reaction between February 2014 and April 2019. In total, 701 (5.8%) had a positive RSV result, including 85 (12.1%) with bacterial coinfection. RSV-bacterial coinfection was associated with an increase in crude in-hospital mortality in patients >65 years old (hazard ratio, 2.94; 95% CI, 1.30-6.60; P = .010). Optimized prevention and management strategies to reduce this burden are needed.

journal_name

Open Forum Infect Dis

journal_title

Open forum infectious diseases

authors

Godefroy R,Giraud-Gatineau A,Jimeno MT,Edouard S,Meddeb L,Zandotti C,Chaudet H,Colson P,Raoult D,Cassir N

doi

10.1093/ofid/ofaa546

subject

Has Abstract

pub_date

2020-11-12 00:00:00

pages

ofaa546

issue

12

issn

2328-8957

pii

ofaa546

journal_volume

7

pub_type

杂志文章

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